CN-122006905-A - Hydroxamic acid flotation collector, and synthetic method and application thereof

Abstract

The invention discloses a hydroxamic acid flotation collector, a synthesis method and application thereof, wherein an amino hydroxamic acid compound is used as a mineral flotation collector to be applied to flotation recovery of valuable metals in nonferrous metals and noble metals containing rare earth, cassiterite, copper oxide and the like, and two functional groups are connected with a hydrocarbon chain through an amino group, so that repulsive force among ligands and repulsive force among surrounding hydration layers are weakened, hydrophobicity of the surface of the mineral is effectively increased, and the mineral flotation recovery performance can be remarkably improved. Compared with the common flotation collector in the prior art, the collector can effectively improve the enrichment and recovery of nonferrous metals such as rare earth, cassiterite, copper oxide and the like and noble metal minerals.

Inventors

• FAN HONGLI
• LI JIAXIANG
• LI ZHILONG
• ZHANG CHANGLEI

Assignees

• 内蒙古科技大学

Dates

Publication Date

20260512

Application Date

20260305

Claims (7)

1. 1. A hydroxamic acid flotation collector is characterized in that the hydroxamic acid flotation collector is an amino hydroxamic acid compound with a structure shown in a formula (1), (1) Wherein R 1 is alkylene, alkenylene, arene or alkyleneoxy, and R 2 is alkyl, alkylene, aryl, naphthyl or alkyleneoxy.
2. 2. A hydroxamic acid flotation collector according to claim 1, wherein R 1 is C 1 -C 8 alkyl, C 2 -C 10 alkylene, C 6 -C 12 aryl or an alkoxyl ether having the structure of formula (2), and R 2 is C 1 -C 8 alkyl, C 2 -C 10 alkylene, C 6 -C 12 aryl or an alkoxyl ether having the structure of formula (2); (2) Wherein R 3 、R 4 is ethylene or propylene, and n is 1-3.
3. 3. A hydroxamic acid flotation collector according to claim 2, wherein R 1 is methylene, ethylene, propylene, hexylene, heptylene, nonylene, allylene or alkenylene.
4. 4. A method of synthesizing a hydroxamic acid flotation collector according to any one of claims 1-3, characterized by the following synthetic route: S1, adding methanol and naphthylamine into a reaction container, uniformly stirring and dispersing, keeping the room temperature, slowly dropwise adding methyl haloacrylate into the reaction container, and reacting for 3 hours; S2, cooling to 25 ℃, adding hydroxylamine hydrochloride under the condition, slowly adding sodium hydroxide, and reacting for 0.5 h after the addition is finished; s3, raising the temperature to 50 ℃ for 3 hours, then lowering the temperature to 5 ℃, adding sulfuric acid into the mixture for acidification at the temperature until the pH value of the solution reaches 5, and raising the temperature to 50 ℃ for 0.5 hours; And S4, filtering the reaction liquid, performing reduced pressure distillation on the filtrate to remove the solvent to obtain a target product crude product, and recrystallizing the crude product for further purification to obtain a purer target product.
5. 5. The method for synthesizing the hydroxamic acid floatation collector according to claim 4, wherein in the step S1, methanol and naphthylamine are added into a reaction container, stirred and dispersed uniformly, the room temperature is maintained, and methyl acrylate is slowly added dropwise into the reaction container for 3 hours, and the synthetic route is as follows: 。
6. 6. use of a hydroxamic acid flotation collector according to any of claims 1-3, in the flotation recovery of valuable metals from non-ferrous and precious metal minerals containing rare earth, cassiterite and copper oxide.
7. 7. The use of a hydroxamic acid flotation collector according to claim 6, wherein the non-ferrous and precious metal minerals comprise one or more of cerium, tin, copper metals.

Description

Hydroxamic acid flotation collector, and synthetic method and application thereof Technical Field The invention belongs to the technical field of metal beneficiation, relates to a hydroxamic acid flotation collector, a synthesis method and application thereof, and particularly relates to application of the hydroxamic acid flotation collector in flotation recovery of valuable metals from nonferrous metals such as rare earth, cassiterite and copper oxide and noble metal minerals. Background Hydroxamic acid compounds have biological activity. In the medical aspect, the hydroxamic acid compound can be used as a medicament to have the effects of easing pain, diminishing inflammation, resisting cancer and the like, and particularly the current increasing of the incidence rate of cancer is continuously carried out, and the research of anticancer active medicaments is concerned at home and abroad. Related experiments prove that the generation and development of malignant tumors are not separated from the imbalance of histone deacetylation states, and the hydroxamic acid inhibitor can improve the acetylation degree of histones, so that the proliferation of tumor cells is selectively inhibited. At present, biochemists at home and abroad have paid attention to the advantages of diversified structures, high activity and strong specificity, and a large number of anticancer drugs are developed in a competitive manner. The safety of administration of suberoylanilide hydroxamic acid (SAHA) and the bioactivity and action mechanism of tumor cells are researched through oral administration or intravenous injection, and the suberoylanilide hydroxamic acid has good inhibition effect on the activity and proliferation of tumor cells, can cause the cells to apoptosis, and has small toxic and side effects on renal functions and blood cells. The synthesized furoyl tin hydroxamate complex is used for researching the anticancer performance, and the result shows that both phenyl and n-butyl furfural tin hydroxamate have good anticancer effect, and the hydroxamate compound can be used as an extractant with higher selectivity in the aspect of metallurgy. And a novel structure of cupped hydroxamic acid is synthesized, which can be used for microassay of Cr (III), mo (VI) and W (VI), sequential separation and liquid-liquid extraction. Experiments show that Cr (III), mo (VI) and W (VI) can be respectively extracted in chloroform solvent in the presence of a large amount of anions and cations when the pH is 4.5 and the hydrochloric acid concentration is 1.5mol/L and 6.0 mol/L. The hydroxamic acid compound also has stable chelation, and can be used as a flocculating agent and a precipitating agent in the field of wastewater treatment. Wang Bi and the like synthesize the polyhydroxyoxime acid from the composite polyacrylamide, hydroxylamine hydrochloride and sodium hydroxide, and are used for treating 25mg/L cadmium-containing wastewater, the removal rate of Cd 2+ is increased along with the increase of the pH value (4-8), and the removal rate of Cd 2+ can reach 94%. The hydroxamic acid can also form a complex with metal ions, has good selective adsorption performance, can be used for enriching and recovering valuable metals, and has wide application prospect. The rare earth elements such as Ce, la, pr and Nd are recovered from the seawater through the adsorption of the polyhydroxy oxime acid, the adsorption effect is obviously stronger than the effect intensity on alkali metals and alkaline earth metals, and the polyhydroxy oxime acid has good selectivity. A large number of practices prove that the hydroxamic acid is an oxidized ore collector with high selectivity, strong collecting capacity, low toxicity and environmental protection, and has good application prospect in the field of mineral flotation. The method is applied to mineral processing industries such as iron oxide ore, zinc oxide ore, columbite, lead zinc ore, rare earth ore, tantalum-niobium ore, tungsten ore, cassiterite, copper oxide ore and the like. Currently, no prior art reports about the use of naphthylamine bis-hydroxamic acid compounds as mineral flotation collectors. Disclosure of Invention Aiming at the defects in the prior art, the invention provides a hydroxamic acid flotation collector, and a synthesis method and application thereof. The first object of the present invention is to provide a hydroxamic acid based flotation collector which is an amino hydroxamic acid based compound having the structure of formula (1), (1) Wherein R 1 is alkylene, alkenylene, arene or alkyleneoxy, and R 2 is alkyl, alkylene, aryl, naphthyl or alkyleneoxy. Preferably, R 1 is C 1-C8 alkyl, C 2-C10 alkenyl, C 6-C12 aryl or an alkoxy ether group having the structure of formula (2), and R 2 is C 1-C8 alkyl, C 2-C10 alkenyl, C 6-C12 aryl or an alkoxy ether group having the structure of formula (2); (2) Wherein R 3、R4 is ethylene or propylene, and n is 1-3. Preferably, R 1 is methylene, ethyle