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CN-122008316-A - Bionic robot autonomous energy supply method mediated by bioactive artificial tissue

CN122008316ACN 122008316 ACN122008316 ACN 122008316ACN-122008316-A

Abstract

The invention provides an autonomous energy supply method of a bionic robot mediated by bioactive artificial tissues, belonging to the technical cross field of synthetic biology and micro robots. The artificial biological tissue adopts a three-layer coaxial spiral splice-free integrated structure, comprises a dynamic shrinkage layer, a coupling power generation layer and a bionic current collection layer from inside to outside, is formed by a microscale 3D forming and interface fusion process, has no metal component, has a core volume of less than or equal to 0.5cm < 3 >, a weight of less than or equal to 5g, has the functions of mechanical shrinkage, biological power generation and electric signal conduction, is matched with special low-viscosity energy liquid, has the pH of 7.2-7.4, has the viscosity of less than or equal to 5mPa and is subjected to permeation energy supply by a spiral gap micro-channel, and the single-time supplementary endurance of more than or equal to 48 hours. The biological self-powered robot integrates the integrated tissue and the special energy liquid, solves the problems of high energy loss, poor biocompatibility and limited microminiaturization of the existing equipment, and can be widely applied to medical minimally invasive implantation, tiny space inspection, unmanned environment monitoring and other scenes.

Inventors

  • YANG WENJUN

Assignees

  • 杨文俊

Dates

Publication Date
20260512
Application Date
20260226

Claims (10)

  1. 1. The bionic robot autonomous energy supply method mediated by the bioactive artificial tissue is characterized by comprising the steps of adopting the bioactive artificial tissue with a three-layer coaxial spiral splice-free integrated structure as an energy conversion and power output core, and realizing the cooperative autonomous operation of the bionic robot power output and self-power generation energy supply through special low-viscosity energy liquid permeation energy supply; The bioactive artificial tissue sequentially comprises a dynamic shrinkage layer, a coupling power generation layer and a bionic current collection layer from inside to outside, no metal electrode component is contained, and the core volume is less than or equal to 0.5cm < 3 >.
  2. 2. The method of claim 1, wherein the dynamic contraction layer is a directionally modified skeletal muscle cell layer or a collagen modified bionic elastic polymer layer, and is capable of achieving directional mechanical contraction and providing linkage power for the coupling power generation layer.
  3. 3. The autonomous energy supply method of claim 1, wherein the coupling power generation layer is a bionic bioelectricity generation cell layer or an electrogenesis microorganism composite layer, and can convert mechanical linkage energy of the dynamic contraction layer into direct current to supply power for the bionic robot.
  4. 4. The autonomous energy supply method according to claim 1, wherein the bionic collector layer is a net-shaped nano conductive biomembrane or a PEDOT: PSS flexible conductive polymer coating, can shrink/stretch synchronously with an integrated tissue, has no risk of conductive fracture, and is excellent in biocompatibility.
  5. 5. The autonomous energy supply method according to claim 1, wherein the special low-viscosity energy liquid comprises, by weight, 5% -8% of glucose, 0.2% -0.4% of potassium chloride, 0.6% -0.8% of sodium chloride, 0.1% -0.3% of a biocompatibility regulator, the balance of sterile deionized water, a pH value of 7.2-7.4, and a viscosity of less than or equal to 5mPa and s.
  6. 6. The autonomous energy supply method according to claim 1 or 5, wherein the special energy liquid permeates to the power contraction layer and the coupling power generation layer through the spiral gap natural micro-channel of the bioactive artificial tissue, and meanwhile, the power supply and the ion conduction reinforcement are realized, and an external liquid storage tank and a pumping device are not needed.
  7. 7. The autonomous energy supplying method according to claim 1, wherein the bioactive artificial tissue is prepared by a microscale 3D molding and interfacial fusion process, the pitch is controlled to be 0.2-0.5mm, the diameter is 1-3mm after compression, and the bioactive artificial tissue can be stretched to 1.8 times of the original length and contracted to 0.6 times of the original length.
  8. 8. The autonomous energy supply method according to claim 1, wherein the special energy liquid is supplemented in a minimally invasive manner, the autonomous endurance time of the bionic robot after single supplementation is more than or equal to 48 hours, and the metabolites are only water and carbon dioxide.
  9. 9. The autonomous energy supply method according to claim 1, wherein the autonomous energy supply process of the bionic robot has no physical splicing redundancy, the energy conversion efficiency is remarkably improved compared with that of the split structural equipment, and the energy supply scene of the microscale runner with the diameter smaller than or equal to 0.1mm can be adapted.
  10. 10. The autonomous power supply method of claim 1, wherein the biomimetic robot is applicable to medical minimally invasive implantation, mini-space inspection or unmanned environmental monitoring scenarios, can pass millimeter-sized narrow spaces and is free from biohazard.

Description

Bionic robot autonomous energy supply method mediated by bioactive artificial tissue Technical Field The invention belongs to the intersection of synthetic biology and micro-robot technology, and particularly relates to an autonomous energy supply method of a bionic robot mediated by bioactive artificial tissues. Background In the field of cross application of synthetic biology and micro-robot technology, bio-driven or self-powered equipment and traditional lithium-powered micro-robots are gradually applied to medical and industrial detection scenes, but the prior art still has significant defects. The existing biological driving/self-powered equipment generally adopts a split type structure, a power layer, a power generation layer and a conductive electrode are separated, so that loss is serious in the energy transmission process, the actions of all layers are difficult to synchronize, the operation efficiency of the equipment is affected, meanwhile, the equipment is mainly provided with a metal conductive electrode, the biocompatibility is poor, rejection reaction is easily caused after the equipment is implanted into a living body, and the equipment cannot be adapted to high-precision scenes such as medical in-vivo implantation. In addition, the viscosity of the energy supply liquid adapted by the existing equipment is high, and the energy supply liquid is difficult to pass through a micro-scale runner, so that the equipment has short endurance time and limited scene suitability. The traditional lithium battery powered micro-robot needs to frequently replace a power supply, is complex in operation, has liquid leakage risk, and cannot stably operate in special scenes such as unattended operation and airtight space. These technical defects make the existing equipment difficult to meet the requirements of medical minimally invasive implantation, tiny space inspection, unmanned environment monitoring and other scenes, and a technical scheme with high energy conversion efficiency, excellent biocompatibility, extremely miniaturization and long endurance is needed, so that the blank of the prior art is filled. Disclosure of Invention In order to solve the technical problems, the invention provides an autonomous energy supply method of a bionic robot mediated by bioactive artificial tissues, which solves the technical problems of high energy loss, poor biocompatibility, limited microminiaturization, short duration and insufficient scene suitability of the traditional biological driving/self-powered equipment and the traditional lithium battery powered micro-robot. The bionic robot autonomous energy supply method mediated by the bioactive artificial tissue comprises the steps of adopting the bioactive artificial tissue with a three-layer coaxial spiral splice-free integrated structure as an energy conversion and power output core, realizing the cooperative autonomous operation of the bionic robot power output and self-power generation energy supply through the special low-viscosity energy liquid permeation energy supply; The bioactive artificial tissue sequentially comprises a dynamic shrinkage layer, a coupling power generation layer and a bionic current collection layer from inside to outside, no metal electrode component is contained, and the core volume is less than or equal to 0.5cm < 3 >. Preferably, the dynamic contraction layer is a directional modified skeletal muscle cell layer or a collagen modified bionic elastic polymer layer, so that directional mechanical contraction can be realized, linkage power is provided for the coupling power generation layer, the coupling power generation layer is a bionic bioelectricity generation cell layer or an electrogenesis microorganism composite layer, and mechanical linkage energy of the dynamic contraction layer can be converted into direct current to supply power for the bionic robot. Preferably, the bionic collector layer is a reticular nano conductive biomembrane or a PEDOT: PSS flexible conductive polymer coating, can synchronously shrink/stretch along with an integrated tissue, has no conductive fracture risk and excellent biocompatibility, and the special low-viscosity energy liquid comprises, by weight, 5% -8% of glucose, 0.2% -0.4% of potassium chloride, 0.6% -0.8% of sodium chloride, 0.1% -0.3% of a biocompatibility regulator, the balance of sterile deionized water, and has a pH value of 7.2-7.4 and a viscosity of less than or equal to 5mPa s. Preferably, the special energy liquid permeates to the power contraction layer and the coupling power generation layer through the spiral gap natural micro-channel of the bioactive artificial tissue, and meanwhile power energy supply and ion conduction reinforcement are realized, and an external liquid storage tank and a pumping device are not needed. Preferably, the bioactive artificial tissue is prepared through a microscale 3D molding and interface fusion process, the screw pitch is controlled to be 0.2-0.5mm, the