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CN-122010273-A - Sustained release preparation based on composite carrier coated calcium peroxide, preparation method and application

CN122010273ACN 122010273 ACN122010273 ACN 122010273ACN-122010273-A

Abstract

The invention discloses a slow-release preparation based on composite carrier coated calcium peroxide, a preparation method and application thereof, belonging to the technical field of aquaculture substrate improvement, wherein the preparation method comprises the following steps of S1, adding a layered silicate clay mineral into water, heating and stirring, then adding an organosilane modifier for reaction, standing for a certain time at constant temperature, and filtering to obtain an activated layered silicate clay mineral; S2, pouring the activated layered silicate clay mineral obtained in the step S1 into a mixed aqueous solution of sodium alginate and food-grade white granulated sugar, stirring to obtain an activated montmorillonite-sodium alginate composite carrier solution, adding calcium peroxide, stirring for a certain time to obtain a calcium peroxide-carrier mixed solution, introducing the calcium peroxide-carrier mixed solution into a syringe, dripping the calcium peroxide-carrier mixed solution into deionized water at normal temperature to prepare pellets with a certain size, and freezing and drying in a segmented mode to obtain the slow-release preparation based on the composite carrier-coated calcium peroxide. It can increase the load of calcium peroxide and the release period of calcium peroxide.

Inventors

  • LIN JUNRUI
  • Lian Shaojun
  • XIONG QI
  • LIU LONG
  • Tan Yikuang
  • WANG YUEJUN
  • CUI XU

Assignees

  • 浙江洁华新材料股份有限公司

Dates

Publication Date
20260512
Application Date
20260122

Claims (10)

  1. 1. The preparation method of the slow-release preparation based on the composite carrier coated calcium peroxide is characterized by comprising the following preparation steps: s1, activating treatment, namely adding the layered silicate clay mineral into water, heating and stirring, adding an organosilane modifier to react for a certain time, standing at a constant temperature, and filtering to obtain an activated layered silicate clay mineral; S2, preparing a calcium peroxide-carrier mixed solution, namely pouring the activated layered silicate clay mineral obtained in the step S1 into a mixed water solution of sodium alginate and food-grade white granulated sugar, heating and stirring to obtain an activated montmorillonite-sodium alginate composite carrier solution, then adding calcium peroxide, and stirring for a certain time to obtain the calcium peroxide-carrier mixed solution; S3, post-treatment, namely introducing the calcium peroxide-carrier mixed solution obtained in the step S2 into a syringe, dripping the calcium peroxide-carrier mixed solution into deionized water at normal temperature to prepare small balls with a certain size, and freezing and drying the small balls in sections to obtain the slow release preparation based on the composite carrier-coated calcium peroxide.
  2. 2. The method for preparing a slow-release preparation based on composite carrier coated calcium peroxide according to claim 1, wherein in the step S1, the layered silicate clay mineral is rectorite, vermiculite or montmorillonite.
  3. 3. The method for preparing a sustained-release preparation based on composite carrier coated calcium peroxide according to claim 1, wherein in the step S1, the organosilane modifier is gamma-aminopropyl triethoxysilane, and the addition amount is 3-7% of the mass of the layered silicate clay mineral.
  4. 4. The method for preparing a slow-release preparation based on composite carrier coated calcium peroxide according to claim 1, wherein the sodium alginate in the step S2 is added in an amount 1-5 times the mass of the layered silicate clay mineral.
  5. 5. The method for preparing the sustained-release preparation based on the composite carrier-coated calcium peroxide of claim 1, wherein the mass ratio of the food-grade white granulated sugar to the sodium alginate in the mixed aqueous solution of the sodium alginate and the food-grade white granulated sugar in the step S2 is 1:1.
  6. 6. The method for preparing a slow-release preparation based on composite carrier coated calcium peroxide according to claim 1, wherein in the step S2, the adding amount of the calcium peroxide is 35-45% of the mass of the activated montmorillonite-sodium alginate composite carrier solution.
  7. 7. The preparation method of the slow-release preparation based on the composite carrier coated calcium peroxide according to claim 1, wherein the step S3 is characterized in that the freezing temperature is-10-30 ℃ and the freezing time is 3-5 hours, and the sectional drying is specifically performed by drying the preparation in a dryer with the vacuum degree of 0.09MPa and 25 ℃ for 3 hours, then heating the preparation to 35 ℃, keeping the vacuum degree of 0.09MPa, and continuing to dry for 2 hours.
  8. 8. The preparation method of the slow-release preparation based on the composite carrier coated calcium peroxide, which is characterized in that in the step S1, the stirring temperature of heating and stirring the layered silicate clay mineral is 200-400 ℃, the heating and stirring time is 1-2h, and the stirring speed is 100-400r/min; In the step S2, the stirring speed is 500-700r/min, the stirring time is 60-90min, the stirring temperature of secondary stirring is 18-25 ℃, the stirring speed of secondary stirring is 300-500r/min, and the stirring time is 30-90min; in the step S3, the dropping speed is 1-4mL/min, and the size of the small ball is 2-4mm.
  9. 9. A slow release preparation based on composite carrier coated calcium peroxide is characterized by being prepared by the preparation method of the slow release preparation based on composite carrier coated calcium peroxide as claimed in any one of claims 1-8.
  10. 10. Use of a slow release formulation based on a composite carrier coated calcium peroxide according to any one of claims 9 in the substrate of a shrimp or crab culture pond.

Description

Sustained release preparation based on composite carrier coated calcium peroxide, preparation method and application Technical Field The invention relates to the technical field of aquaculture substrate improvement, in particular to a montmorillonite-sodium alginate composite coated high-load calcium peroxide aquaculture substrate improvement preparation and a preparation method and application thereof. Background In the aquaculture process, organic matters such as residual baits, feces, animal and plant residues and the like are continuously deposited at the bottom of the pond, toxic substances such as ammonia nitrogen, hydrogen sulfide, nitrite and the like are easily decomposed in an anaerobic environment, meanwhile, sediment dissolved oxygen suddenly drops (often <2 mg/L), and typical diseases such as 'climbing edges (anoxic stress behavior)' and 'stealing death (chronic poisoning death)' of shrimps and crabs are caused, so that the survival rate is reduced. The reaction formula of the calcium peroxide (CaO 2) serving as a green oxidant and an oxygen release agent is 2CaO 2+2H2O==2Ca(OH)2+O2 ∈ when meeting water, and the method has the double advantages that 1, the oxygen is continuously released, 2 and the pH value of the bottom mud can be moderately adjusted by the product calcium hydroxide, so that CaO 2 is regarded as one of the main flow bottom quality modifier values. However, the direct throwing of calcium peroxide has two main core problems that 1, the specific surface area of the calcium peroxide powder is large, the calcium peroxide powder reacts rapidly after contacting with water, most of oxygen escapes from the upper layer in the water body, not only the sediment can not be reached to play a role, but also the problem of oxygen enrichment and sediment hypoxia of the water body easily occurs, secondly, calcium hydroxide generated by the calcium peroxide is easy to be strong electrolyte, the throwing is easy to cause local concentration to be too high, thereby leading to the pH rising of the sediment (more than 9.0), and the shrimp and crab larvae (the suitable pH of the shrimp and crab larvae is 7.6-8.6, and the critical tolerance upper limit is 8.8) generate alkaline stress. In order to solve the problems, the prior art optimizes the throwing effect of calcium peroxide by modifying technologies such as 'carrier wrapping' or 'mineral compounding', but the proposal has obvious short plates: The single sodium alginate coated calcium peroxide technology adopts sodium alginate as a gel mechanism, and water is blocked by a gel network, so that the slow release and oxygen release of the calcium peroxide are realized, and the slow release period is 5-7 days. However, in the technology, the loading amount of the calcium peroxide is only 15% -20% (gel breakage is caused by excessive calcium peroxide), so that the bottom modifying effect can be achieved only by large-scale throwing, and the cultivation cost is increased. In addition, the method needs to introduce a large amount of metal ions as a cross-linking agent to enable the slow-release agent to be stable enough, but after the preparation is finished, the adopted metal ions can remain on the surfaces of the pellets, so that the local ion concentration of the bottom mud is abnormal. The single montmorillonite is used for absorbing calcium peroxide, bentonite for aquatic products is used as a carrier, the technology utilizes the high density (2.6-2.8 g/cm <3 >) of montmorillonite to accelerate particle sedimentation (sedimentation within 1-2 minutes), and simultaneously, calcium peroxide reaction is delayed through interlayer absorption. However, in the technology, the superphosphate is only attached to the surface and the interlayer of the montmorillonite through physical adsorption, so that the load capacity is less than or equal to 25%, the superphosphate is easy to fall off in a water body, the early-stage oxygen release is too fast, the later-stage sediment is insufficient in dissolved oxygen, and meanwhile, a large amount of calcium hydroxide is generated, so that the pH fluctuation of the sediment exceeds the proper pH range (7.6-8.6) of young shrimps and crabs. In order to solve the problems, a bentonite and sodium alginate composite coated calcium peroxide and a preparation method thereof are presented, but the method needs to add various metal chloride salt solutions, but in the technology, the effective components of the calcium peroxide are low, and the requirements of aquaculture cannot be met. In conclusion, the existing calcium peroxide substrate improvement technology generally has the defects of low loading capacity, short slow release period, weak pH buffering capacity and poor carrier stability, and is difficult to meet the aquaculture requirements of high efficiency substrate improvement, controllable cost and ecological safety. Therefore, developing a calcium peroxide composite preparation with high loading capacity, long-acti