Search

CN-122010670-A - Preparation method of myrcene

CN122010670ACN 122010670 ACN122010670 ACN 122010670ACN-122010670-A

Abstract

The invention relates to a preparation method of myrcene. The invention provides a calcium oxide-copper/aluminum oxide catalyst columnar tube, which is prepared by immersing a columnar hollow aluminum oxide tube in a mixed water solution of copper nitrate and calcium nitrate, taking out, dehydrating, roasting, introducing hydrogen into the tube, and heating to obtain the calcium oxide-copper/aluminum oxide catalyst columnar tube. The calcium oxide-copper/aluminum oxide catalyst disclosed by the invention can effectively catalyze beta-pinene to crack and generate myrcene, so that the application value of myrcene is improved.

Inventors

  • SU JIANGBO
  • DENG XINGUI
  • WEI JINGBO
  • YANG BIN
  • XIE ZHENCHENG

Assignees

  • 福建南平青松化工有限公司

Dates

Publication Date
20260512
Application Date
20260115

Claims (10)

  1. 1. The calcium oxide-copper/aluminum oxide catalyst columnar tube is characterized in that the calcium oxide-copper/aluminum oxide catalyst columnar tube is prepared by the following steps: Immersing the columnar hollow aluminum oxide tube in a mixed water solution of copper nitrate and calcium nitrate, taking out, dehydrating, roasting, introducing hydrogen into the tube, and heating to obtain the columnar calcium oxide-copper/aluminum oxide catalyst tube.
  2. 2. The calcia-copper/alumina catalyst column tube according to claim 1, wherein the copper nitrate concentration is 1.5-2.3mol/L, preferably 1.6-2.0mol/L, more preferably 1.7-1.9mol/L, most preferably 1.8mol/L; The concentration of the calcium nitrate is 0.5 to 1.2mol/L, preferably 0.6 to 1.0mol/L, more preferably 0.7 to 0.9mol/L, and most preferably 0.8mol/L.
  3. 3. The calcia-copper/alumina catalyst column tube according to claim 1, wherein the temperature of dehydration is 100-120 ℃, preferably 105-115 ℃, more preferably 110 ℃; The dehydration time is 8-12 hours, preferably 9-11 hours, more preferably 9.5-10.5 hours, most preferably 10 hours.
  4. 4. The calcia-copper/alumina catalyst tubes according to claim 1, wherein the calcination temperature is 420-460 ℃, preferably 430-450 ℃, more preferably 440 ℃; the calcination time is 6 to 8 hours, preferably 6.5 to 7.5 hours, more preferably 7 hours.
  5. 5. The calcia-copper/alumina catalyst column tube according to claim 1, wherein the heating temperature is 280-360 ℃, preferably 300-340 ℃, more preferably 310-330 ℃, most preferably 320 ℃; the heating time is 7-9 hours, preferably 7.5-8.5 hours, more preferably 8 hours.
  6. 6. The calcia-copper/alumina catalyst pillar tube according to claim 1, wherein said calcia-copper/alumina catalyst pillar tube is prepared by the following method: Immersing the columnar hollow aluminum oxide tube in a mixed water solution of 1.8 mol/L copper nitrate and 0.8mol/L calcium nitrate for 18 hours, taking out, dehydrating at 110 ℃ for 10 hours, roasting at 440 ℃ for 7 hours, then introducing hydrogen into the tube, and heating at 320 ℃ for 8 hours to obtain the calcium oxide-copper/aluminum oxide catalyst columnar tube.
  7. 7. A method for preparing myrcene, which is characterized by comprising the following steps: the beta-pinene is catalyzed in the calcium oxide-copper/aluminum oxide catalyst columnar tube according to claim 1 to obtain myrcene.
  8. 8. The process according to claim 7, wherein the temperature of the reaction is 340-420 ℃, preferably 350-410 ℃, more preferably 360-400 ℃, more preferably 370-390 ℃, most preferably 380 ℃; The pressure of the reaction is 10-30KPa, preferably 15-25KPa, more preferably 18-22KPa, more preferably 19-21KPa, most preferably 20KPa.
  9. 9. The method of claim 7, wherein the method for preparing myrcene comprises: Beta-pinene is catalyzed in a calcium oxide-copper/aluminum oxide catalyst columnar tube at the temperature of 370-390 ℃ and the reaction pressure of 19-21KPa, and laurene is obtained after condensation.
  10. 10. The method of claim 7, wherein the method for preparing myrcene comprises: beta-pinene is catalyzed in a calcium oxide-copper/aluminum oxide catalyst columnar tube under the conditions of 380 ℃ and 20KPa reaction pressure, and laurene is obtained after condensation.

Description

Preparation method of myrcene Technical Field The invention relates to the field of pharmaceutical chemicals, in particular to a preparation method of myrcene. Background Myrcene, also called myrcene, is a volatile aromatic compound which is present in laurel leaf essential oil, cinnamon oil, maple oil, cedar wood oil, spruce oil, turpentine, lemon grass oil, lemon oil and the like, is widely used in the perfume industry or as a food additive in foods and beverages, and in addition, myrcene has analgesic, antioxidant, anti-inflammatory, antibacterial and other medical effects, so that myrcene is widely used in fields such as perfumes, medicines and foods. Although myrcene has wide application value in fields of perfume, medicine, food and the like, the prior art lacks a method capable of effectively preparing myrcene, so that application of myrcene is limited, and how to develop a method capable of effectively preparing myrcene becomes a research hot spot. Accordingly, there is a need in the art to develop a process that can effectively produce myrcene. Disclosure of Invention The invention aims to provide a calcium oxide-copper/aluminum oxide catalyst columnar tube and a method for effectively preparing myrcene by using the same. The first aspect of the invention provides a calcium oxide-copper/aluminum oxide catalyst columnar tube, which is prepared by the following steps: Immersing the columnar hollow aluminum oxide tube in a mixed water solution of copper nitrate and calcium nitrate, taking out, dehydrating, roasting, introducing hydrogen into the tube, and heating to obtain the columnar calcium oxide-copper/aluminum oxide catalyst tube. Preferably, the immersion time is 16-20 hours, preferably 17-19 hours, more preferably 18 hours. Preferably, the concentration of copper nitrate is 1.5 to 2.3mol/L, preferably 1.6 to 2.0mol/L, more preferably 1.7 to 1.9mol/L, most preferably 1.8mol/L. Preferably, the concentration of said calcium nitrate is 0.5-1.2mol/L, preferably 0.6-1.0mol/L, more preferably 0.7-0.9mol/L, most preferably 0.8mol/L. Preferably, the temperature of the dehydration is from 100 to 120 ℃, preferably from 105 to 115 ℃, more preferably 110 ℃. Preferably, the time for dehydration is 8-12 hours, preferably 9-11 hours, more preferably 9.5-10.5 hours, most preferably 10 hours. Preferably, the firing temperature is 420-460 ℃, preferably 430-450 ℃, more preferably 440 ℃. Preferably, the calcination time is 6 to 8 hours, preferably 6.5 to 7.5 hours, more preferably 7 hours. Preferably, the temperature of the heating is 280-360 ℃, preferably 300-340 ℃, more preferably 310-330 ℃, most preferably 320 ℃. Preferably, the heating is for a period of time of 7 to 9 hours, preferably 7.5 to 8.5 hours, more preferably 8 hours. Preferably, the calcium oxide-copper/aluminum oxide catalyst columnar tube is prepared by the following method: Immersing the columnar hollow aluminum oxide tube in a mixed water solution of 1.6-2.0 mol/L copper nitrate and 0.6-1.0mol/L calcium nitrate for 17-19h, taking out, dehydrating at 100-120 ℃ for 9-11h, roasting at 430-450 ℃ for 6-8h, introducing hydrogen into the tube, and heating at 310-330 ℃ for 7-9h to obtain the calcium oxide-copper/aluminum oxide catalyst columnar tube. Preferably, the calcium oxide-copper/aluminum oxide catalyst columnar tube is prepared by the following method: Immersing the columnar hollow aluminum oxide tube in a mixed water solution of 1.8 mol/L copper nitrate and 0.8mol/L calcium nitrate for 18 hours, taking out, dehydrating at 110 ℃ for 10 hours, roasting at 440 ℃ for 7 hours, then introducing hydrogen into the tube, and heating at 320 ℃ for 8 hours to obtain the calcium oxide-copper/aluminum oxide catalyst columnar tube. The second aspect of the invention provides a preparation method of myrcene, which comprises the following steps: and (3) carrying out catalytic reaction on the beta-pinene in the calcium oxide-copper/aluminum oxide catalyst columnar tube to obtain the myrcene. Preferably, the temperature of the reaction is 340-420 ℃, preferably 350-410 ℃, more preferably 360-400 ℃, more preferably 370-390 ℃, most preferably 380 ℃. Preferably, the pressure of the reaction is from 10 to 30KPa, preferably from 15 to 25KPa, more preferably from 18 to 22KPa, more preferably from 19 to 21KPa, most preferably 20KPa. Preferably, the preparation method of myrcene comprises the following steps: Beta-pinene is catalyzed in a calcium oxide-copper/aluminum oxide catalyst columnar tube at the temperature of 370-390 ℃ and the reaction pressure of 19-21KPa, and laurene is obtained after condensation. Preferably, the preparation method of myrcene comprises the following steps: beta-pinene is catalyzed in a calcium oxide-copper/aluminum oxide catalyst columnar tube under the conditions of 380 ℃ and 20KPa reaction pressure, and laurene is obtained after condensation. Preferably, the laurene content prepared by the method is more than 82 percent and 82-90 percent. Pr