Search

CN-122011646-A - Contact lens based on up-conversion luminescent nano material and preparation method thereof

CN122011646ACN 122011646 ACN122011646 ACN 122011646ACN-122011646-A

Abstract

The invention provides a contact lens based on an up-conversion luminescence nano material and a preparation method thereof, and belongs to the technical field of contact lenses. The contact lens comprises a contact lens substrate and a core-shell structure up-conversion luminescent nano material dispersed in the contact lens substrate, wherein the core-shell structure up-conversion luminescent nano material is mainly prepared from chitosan and rare earth up-conversion luminescent nano particles. According to the invention, the rare earth up-conversion luminescent nano particles are packaged in the chitosan matrix to form the up-conversion luminescent nano material with a core-shell structure, and the chitosan shell layer forms a natural refractive index gradient transition layer between the luminescent nano particles and the contact lens base material, so that the reflection loss is effectively reduced, and the emergent rate of visible light generated by up-conversion and the light transmittance of the contact lens are improved.

Inventors

  • Tang Yinjiao
  • XIE ENKE
  • ZHANG JUN
  • ZHAN YUCAI

Assignees

  • 甘肃康视丽隐形眼镜有限公司

Dates

Publication Date
20260512
Application Date
20260204

Claims (9)

  1. 1. A contact lens based on an up-conversion luminescent nanomaterial, characterized in that the contact lens comprises a contact lens substrate and a core-shell structured up-conversion luminescent nanomaterial dispersed in the contact lens substrate; the up-conversion luminescent nano material with the core-shell structure is mainly prepared from chitosan and rare earth up-conversion luminescent nano particles.
  2. 2. The upconversion luminescent nanomaterial-based contact lens according to claim 1, wherein the rare earth upconversion luminescent nanoparticle comprises CaF 2 ：Er 3+ nanoparticle, naYF 4 :er, ho nanoparticle, naYF 4 :er nanoparticle or NaYF 4 :er, tm nanoparticle.
  3. 3. The up-conversion luminescent nanomaterial-based contact lens of claim 1 or 2, wherein the particle size of the rare earth up-conversion luminescent nanoparticles is 10-100 nm.
  4. 4. The method for preparing the contact lens based on the up-conversion luminescent nanomaterial according to any one of claims 1 to 3, comprising the following steps: (1) Dispersing rare earth up-conversion luminescent nano particles in chitosan solution, and performing uniaxial electrostatic spraying and freeze drying to obtain a core-shell structured up-conversion luminescent nano material; (2) Mixing methacryloxypropyl tris (trimethylsiloxy) silane, N-dimethylacrylamide, N-vinylpyrrolidone, hydroxyethyl methacrylate, ethylene glycol dimethacrylate and an initiator to obtain a mixed solution; (3) And dispersing the up-conversion luminescent nano material with the core-shell structure in water, mixing the obtained dispersion liquid with the mixed liquid, and performing a crosslinking reaction to obtain the contact lens.
  5. 5. The method for preparing the contact lens based on the up-conversion luminescent nano material, which is characterized in that in the step (1), the concentration of the chitosan solution is 10-20 mg/mL, and the content of the rare earth up-conversion luminescent nano particles in the chitosan solution is 4-6 mg/mL.
  6. 6. The method for preparing the contact lens based on the up-conversion luminescent nanomaterial according to claim 4 or 5, wherein in the step (1), the technological parameters of the uniaxial electrostatic spraying are that the voltage is 5-15 kV, the pushing flow rate is 0.1-1 mm/min, and the receiving distance is 5-10 cm.
  7. 7. The method for preparing the contact lens based on the up-conversion luminescent nanomaterial of claim 6, wherein the mass ratio of the methacryloxypropyl tris (trimethylsiloxy) silane, N-dimethylacrylamide, N-vinylpyrrolidone, hydroxyethyl methacrylate, ethylene glycol dimethacrylate and the initiator is 30-40:20-40:10-15:8-15:0.3-0.8:0.1-0.6.
  8. 8. The preparation method of the contact lens based on the up-conversion luminescent nanomaterial according to claim 5 or 7, wherein the mass content of the up-conversion luminescent nanomaterial of the core-shell structure in the mixed solution is 6-12%.
  9. 9. The method for preparing the contact lens based on the up-conversion luminescent nanomaterial according to claim 8, wherein the temperature of the crosslinking reaction is 80-120 ℃ and the time is 20-60 min.

Description

Contact lens based on up-conversion luminescent nano material and preparation method thereof Technical Field The invention relates to the technical field of contact lenses, in particular to a contact lens based on an up-conversion luminescence nanomaterial and a preparation method thereof. Background The up-conversion luminescent material (such as rare earth doped nano particles) is used as a nonlinear optical material, and can convert low-energy infrared photons into high-energy visible photons through nonlinear processes such as multiphoton absorption and the like, so that the visible photons are captured by retina cells, and finally, infrared light visualization is realized. The doping of such upconverting nanoparticles into biocompatible polymers to produce wearable devices (e.g., contact lenses) has great potential applications, such as assisting drivers in viewing in night dimming conditions, enhancing night reconnaissance, and enhancing the visual perception of nyctalopia and cataract patients in low light environments. However, the nanoparticles are directly dispersed in the contact lens base material, and the problem of uneven dispersion affecting the transmittance of the contact lens is caused. Therefore, research on a contact lens based on up-conversion luminescent nano material and a preparation method thereof is of great significance in improving the light transmittance of the contact lens. Disclosure of Invention The invention aims to provide a contact lens based on an up-conversion luminescent nano material and a preparation method thereof, so as to solve the problems of uneven dispersion and low light transmittance of the contact lens after nano particles are added in the prior art. In order to achieve the above object, the present invention provides the following technical solutions: The invention provides a contact lens based on an up-conversion luminescence nanomaterial, which comprises a contact lens substrate and a core-shell structure up-conversion luminescence nanomaterial dispersed in the contact lens substrate; the up-conversion luminescent nano material with the core-shell structure is mainly prepared from chitosan and rare earth up-conversion luminescent nano particles. Preferably, the rare earth up-conversion luminescent nanoparticle comprises CaF 2：Er3+ nanoparticle, naYF 4:Er, ho nanoparticle, naYF 4:Er nanoparticle or NaYF 4:Er, tm nanoparticle. Preferably, the particle size of the rare earth up-conversion luminescence nano particles is 10-100 nm. The invention also provides a preparation method of the contact lens based on the up-conversion luminescent nanomaterial, which comprises the following steps: (1) Dispersing rare earth up-conversion luminescent nano particles in chitosan solution, and performing uniaxial electrostatic spraying and freeze drying to obtain a core-shell structured up-conversion luminescent nano material; (2) Mixing methacryloxypropyl tris (trimethylsiloxy) silane, N-dimethylacrylamide, N-vinylpyrrolidone, hydroxyethyl methacrylate, ethylene glycol dimethacrylate and an initiator to obtain a mixed solution; (3) And dispersing the up-conversion luminescent nano material with the core-shell structure in water, mixing the obtained dispersion liquid with the mixed liquid, and performing a crosslinking reaction to obtain the contact lens. Preferably, in the step (1), the concentration of the chitosan solution is 10-20 mg/mL, and the content of the rare earth up-conversion luminescence nano particles in the chitosan solution is 4-6 mg/mL. Preferably, in the step (1), the technological parameters of the uniaxial electrostatic spraying are that the voltage is 5-15 kV, the pushing flow rate is 0.1-1 mm/min, and the receiving distance is 5-10 cm. Preferably, the mass ratio of the methacryloxypropyl tris (trimethylsiloxy) silane, N-dimethylacrylamide, N-vinylpyrrolidone, hydroxyethyl methacrylate, ethylene glycol dimethacrylate and the initiator is 30-40:20-40:10-15:8-15:0.3-0.8:0.1-0.6. Preferably, the mass content of the up-conversion luminescent nano material with the core-shell structure in the mixed solution is 6-12%. Preferably, the temperature of the crosslinking reaction is 80-120 ℃ and the time is 20-60 min. The invention has the beneficial effects that: (1) According to the invention, the rare earth up-conversion luminescent nano particles are packaged in the chitosan matrix by adopting a uniaxial electrostatic spraying technology, so that the up-conversion luminescent nano material with a core-shell structure is formed, and the chitosan shell layer forms a natural refractive index gradient transition layer between the luminescent nano particles and the contact lens substrate, so that the reflection loss is effectively reduced, and the emergent rate of visible light generated by up-conversion is improved. (2) The invention obviously improves the light transmittance of the contact lens by adding the up-conversion luminescent nano material with the core-she