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CN-122016405-A - Sampling detection device and sampling method for biological sample

CN122016405ACN 122016405 ACN122016405 ACN 122016405ACN-122016405-A

Abstract

The invention discloses a sampling detection device and a sampling method for biological samples, which belong to the technical field of sampling equipment and are technically characterized by comprising a first connecting table, wherein the stability of the sampling process is enhanced through a supporting control mechanism, the loss and pollution of the samples are avoided, meanwhile, the operation threshold is reduced, the sampling efficiency and the standardization level are improved, the control variables can be well controlled through the extending control mechanism and the sampling control mechanism, the credibility of experimental data is improved, the adaptation to the experimental requirements of batches is convenient, the samples after multi-barrel sampling can directly correspond to multi-channel detection equipment, the sample transferring link is reduced, the efficiency of the whole experimental process is further improved, in addition, the adjustable extending and synchronous control sampling mode jointly improves the applicability of the device in complex biological experiments, provides a sampling solution with scientificity and high efficiency for scientific researchers, and has the advantages of controllable sampling and high sampling efficiency.

Inventors

  • LIN CHUN
  • GAN JIANGANG
  • CHEN HONGYE
  • CHEN ZEQIN
  • HUANG SHANSHAN
  • ZENG YINZHU
  • WANG SIPING
  • ZHENG XIAOHU
  • WANG ZHIYING

Assignees

  • 广东岭南职业技术学院

Dates

Publication Date
20260512
Application Date
20260226

Claims (8)

  1. 1. The utility model provides a sampling detection device of biological sample, includes first connection platform (1), its characterized in that, install second connection platform (2) on first connection platform (1), movable mounting has rotary disk (3) on second connection platform (2), the outside movable mounting of first connection platform (1) has a plurality of to be used for sampling tube (18) that the sample detected, be provided with sample needle tubing (25) on sample tube (18), still include: The extension control mechanism is arranged at the joint of the second connecting table (2) and the first connecting table (1) and is used for driving the sampling tube (18) to extend and shrink, the extension control mechanism comprises a driving rod (13) for driving the sampling tube (18) to extend and shrink, the sampling tube (18) is fixedly arranged at one end of the driving rod (13), the driving rod (13) is in limiting sliding connection with the second connecting table (2) through a first sliding rod (14), and a curved groove (4) for driving the driving rod (13) on the first sliding rod (14) to move is formed in the rotating disc (3); The sampling control mechanism is arranged at the joint of the sampling tube (18) and the first connecting table (1) and is used for driving a sampling needle tube (25) on the sampling tube (18) to perform sampling treatment, the sampling control mechanism comprises a lifting guide column (19) for pumping liquid and driving, the lifting guide column (19) is fixedly arranged at one end of the butt joint rod (12), and the other end of the butt joint rod (12) is connected with a lifting table (9) for lifting control; The support control mechanism is arranged on the first connecting table (1) and used for driving the lower part of the first connecting table (1) to carry out support control treatment, the support control mechanism comprises a first support arm (32) and a second support arm (33) which are used for support connection, the first support arm (32) and the second support arm (33) are rotationally connected through a first connecting shaft (34), one ends of the first support arm (32) and the second support arm (33) are movably provided with a third support arm (36) used for lifting, and the bottom of the third support arm (36) is provided with a second support bottom plate (39) used for supporting.
  2. 2. The sampling and testing device for biological samples according to claim 1, characterized in that the extension control mechanism further comprises a second sliding rod (15) for driving the driving rod (13) to extend in a guiding way, the second sliding rod (15) is fixedly installed on the driving rod (13), a third sliding groove (16) which is connected with the second sliding rod (15) in an adapting sliding way is formed in the first connecting table (1), a first sliding groove (7) which is connected with the first sliding rod (14) in an adapting sliding way is formed in the second connecting table (2), and a second sliding groove (8) which is connected with the driving rod (13) in an adapting sliding way is formed in the second connecting table (2).
  3. 3. The sampling and testing device for biological samples according to claim 2, characterized in that the extension control mechanism further comprises a second motor (44) for driving the rotary disk (3) to rotate, a plurality of internal teeth (45) meshed with the rotary gear (41) are arranged on the inner side of the rotary disk (3), the rotary gear (41) is rotatably mounted on a second fixing seat (46) through a fourth connecting shaft (42), the second fixing seat (46) is fixedly mounted on the outer side of the second connecting table (2), the fourth connecting shaft (42) is rotatably connected with an output shaft of the second motor (44) through a bevel gear pair (43), and the second motor (44) is fixedly mounted inside the second connecting table (2).
  4. 4. The sampling and testing device for biological samples according to claim 1, wherein the sampling control mechanism further comprises a piston (24) for drawing liquid, the piston (24) is connected to a fixing plate (21) in a limiting sliding manner through a piston rod (23), the fixing plate (21) is fixedly installed in the sampling tube (18), an air guide hole (22) is formed in the fixing plate (21), and one end of the piston rod (23) is fixedly connected with a lifting guide column (19) through a traction rod (20).
  5. 5. The sampling detection device for biological samples according to claim 4, wherein the sampling control mechanism further comprises a first electric push rod (6) for driving the lifting guide column (19) to lift and connect, the lifting guide column (19) is fixedly connected with a connecting sleeve (11) through a butt joint rod (12), the connecting sleeve (11) is fixedly installed on a lifting table (9) through a multistage telescopic rod (10), the connecting sleeve (11) is sleeved on a second sliding rod (15), a fourth sliding groove (17) for adapting the butt joint rod (12) in a sliding manner is formed in the first connecting table (1), a sixth sliding groove (47) for adapting the butt joint rod (12) in a sliding manner is formed in the sampling cylinder (18), the lifting table (9) is fixedly connected with an output end of the first electric push rod (6), the first electric push rod (6) is fixedly installed on a second connecting table (2), and a position avoiding groove (5) for avoiding the first electric push rod (6) is formed in the rotating disc (3).
  6. 6. The sampling and testing device according to claim 1, wherein the support control mechanism further comprises a lifting sleeve (31) for driving the third support arm (36) to perform shrinkage support, the lifting sleeve (31) is in threaded connection with the screw rod (27), the other end of the first support arm (32) is rotatably connected with the lifting sleeve (31), the other end of the second support arm (33) is rotatably connected with the first fixing seat (28), the first fixing seat (28) is fixedly mounted on the first connecting table (1) through a plurality of fixing rods (40), one end of the second support arm (33) is rotatably connected with one end of the third support arm (36) through a second connecting shaft (35), one end of the first support arm (32) is in limit sliding connection with the third support arm (36) through a third connecting shaft (38), a fifth sliding groove (37) which is in adaptive sliding connection with the third connecting shaft (38) is formed in the third support arm (36), and the other end of the third support arm (36) is fixedly connected with the second support base plate (39).
  7. 7. The sampling and testing device for biological samples according to claim 6, wherein the support control mechanism further comprises a first support bottom plate (30) for lifting the bottom, the first support bottom plate (30) is fixedly connected with the output end of a second electric push rod (29), the second electric push rod (29) is fixedly installed on the first fixing seat (28), the screw rod (27) is fixedly connected with the output shaft of the first motor (26), and the first motor (26) is fixedly installed on the first connecting table (1).
  8. 8. A sampling method of a sampling and detecting device for a biological sample, applied to the sampling and detecting device for a biological sample according to any one of claims 1 to 7, characterized in that the sampling method of the sampling and detecting device for a biological sample comprises the steps of: The second electric push rod (29) drives the first supporting bottom plate (30) to descend for centering of the device, the output shaft of the first motor (26) drives the screw rod (27) to rotate according to the position required for sampling detection, the lifting sleeve (31) is lifted on the screw rod (27), the lifting sleeve (31) moves downwards, the second supporting bottom plate (39) on the third supporting arm (36) moves and expands, the supporting range of the second supporting bottom plate (39) is lifted, and the height regulation of the second electric push rod (29) driving the first supporting bottom plate (30) is completed, so that the device performs stable supporting sampling treatment; According to the sampling range of the sampling needle tube (25) on the sampling tube (18), the output shaft of the second motor (44) works to enable the rotary gear (41) on the fourth connecting shaft (42) to rotate, so as to finish the regulation and control rotation of the rotary disc (3), and the driving rod (13) drives the sampling needle tube (25) on the sampling tube (18) to perform extension and contraction control, so as to finish the sampling extension and contraction adjustment; and thirdly, sampling, namely lifting the lifting table (9) by the first electric push rod (6), lifting the piston (24) on the piston rod (23), and completing sampling and extracting treatment of the biological sample below, wherein the sampling treatment of different positions is completed on the basis of ensuring the same time sampling.

Description

Sampling detection device and sampling method for biological sample Technical Field The invention relates to the field of sampling equipment, in particular to a sampling detection device and a sampling method for biological samples. Background The sampling and detection of biological samples are the core links in the fields of modern biological medicine, clinical diagnosis, food safety monitoring, environmental monitoring and the like, and the accuracy and the timeliness of the results directly determine the scientificity and the reliability of subsequent decisions. With the continuous upgrade of requirements of accurate medical treatment, rapid screening and the like, sampling detection technology of biological samples (such as blood, saliva, tissue fluid, food residues, environmental microorganisms and the like) has become a key support technology for promoting the development of related fields, and is widely focused by global scientific research institutions and industries. The patent application document in China with the publication number of CN111893031B is specifically disclosed and comprises a support flat plate, an upper pressing plate and an extraction mechanism, a plurality of first strip holes are uniformly formed in the support flat plate along the circumferential direction of the support flat plate, the first strip holes are in one-to-one correspondence with the extraction mechanism, a sliding block is arranged between the extraction mechanism and the first strip holes, the sliding block is in sliding connection with the first strip holes, the extraction mechanism comprises an outer shell, an inner shell and a piston, and the outer shell penetrates through the sliding block and is in sliding connection with the sliding block. The sampling device can realize sampling treatment of biological samples, but has the core value of providing objective basis for subsequent judgment through accurate analysis of target components in the samples, and the premise of ensuring 'variable controllability' of sampling links, especially 'sampling time synchronism' and 'position moving distance consistency', directly determines the comparability of the samples and the credibility of detection results, but has the defects that firstly, the sampling device cannot well control the variables, the distance regulation of the sampling is manually carried out, the position is fixed through a nut, the detection efficiency of the subsequent sampling is greatly influenced, secondly, when the samples are detected, a plurality of pistons are required to be drawn by a single person for multiple times, or a plurality of pistons are required to be drawn by a single person for single drawing, the subsequent detection is carried out on the control variables which are not very good, the labor intensity is high, the sampling efficiency is greatly reduced, and the applicability is poor, so that the requirement of practical use is not met. Therefore, there is a need to provide a sampling and detecting device and a sampling method for biological samples, which aim to solve the above problems. Disclosure of Invention Aiming at the defects existing in the prior art, the embodiment of the invention aims to provide a sampling detection device and a sampling method for biological samples, which aim to solve the technical problems in the background art. In order to achieve the above purpose, the present invention provides the following technical solutions: The utility model provides a sampling detection device of biological sample, includes first connection platform, install the second connection bench on the first connection platform, movable mounting has the rotary disk on the second connection bench, the outside movable mounting of first connection bench has a plurality of to be used for the sampling tube that the sample detected, be provided with the sample needle tubing on the sampling tube, still include: The extension control mechanism is arranged at the joint of the second connecting table and the first connecting table and is used for driving the sampling tube to extend and shrink, the extension control mechanism comprises a driving rod for driving the sampling tube to extend and shrink, the sampling tube is fixedly arranged at one end of the driving rod, the driving rod is connected to the second connecting table in a limiting sliding manner through a first sliding rod, and a curved groove for driving the driving rod on the first sliding rod to move is formed in the rotating disc; The sampling control mechanism is arranged at the joint of the sampling tube and the first connecting table and is used for driving the sampling needle tube on the sampling tube to perform sampling treatment, the sampling control mechanism comprises a lifting guide column used for liquid pumping driving, the lifting guide column is fixedly arranged at one end of the docking rod, and the other end of the docking rod is connected with a lifting table used f