CN-122024832-A - DNA multidimensional genetic intelligent matching pursuit system, method, storage medium and electronic equipment

CN122024832ACN 122024832 ACN122024832 ACN 122024832ACN-122024832-A

Abstract

The invention discloses a DNA multidimensional intelligent matching pursuit system, a method, a storage medium and electronic equipment, wherein the system comprises a case management module, a multi-mode data import module, a target crowd library construction module, a multidimensional intelligent computing module, a result output and sorting module, a target crowd library and a multidimensional intelligent sorting module, wherein the case management module is used for creating a case file, the multi-mode data import module is used for providing an input interface of DNA-STR data, the target crowd library construction module is used for creating a target crowd library and storing the DNA-STR data of the target crowd into the target crowd library, the multidimensional intelligent computing module is used for calling a preset standardized authority algorithm to calculate the relatedness according to the target crowd library and a material to be analyzed selected by a user from the case file, and the result output and sorting module is used for outputting analysis results containing relatedness indexes and intelligently sorting the analysis results according to the sequence of the relatedness indexes from high to low.

Inventors

QIN YE
BA HUAJIE

Assignees

北京博安智联科技有限公司

Dates

Publication Date: 20260512
Application Date: 20260211

Claims (10)

1. A DNA multidimensional genetic intelligent matching pursuit system, characterized by comprising the following steps: The case management module is used for creating a case file, wherein the case file comprises a case number, a case name and a receiving date; The multi-mode data import module is used for providing an input interface of DNA-STR data, and the import mode of the multi-mode data import module comprises CODIS file import, manual input and picture identification import; the target crowd library construction module is used for creating a target crowd library and storing DNA-STR data of a target crowd into the target crowd library by calling the multi-mode data import module; The multi-dimensional affinity calculation module is used for calling a preset standardized authority algorithm to calculate the affinity according to a target crowd library and the material to be analyzed selected from the case files by a user, wherein the affinity comprises primary affinity two-body, secondary affinity and tertiary affinity calculation and homotypic comparison; the result output and sorting module is used for outputting analysis results containing the genetic index and intelligently sorting the analysis results according to the sequence from high to low of the genetic index values.
2. The DNA multidimensional intelligent tracking system according to claim 1, wherein the picture recognition and introduction method specifically comprises: acquiring picture data containing genotyping content; Identifying loci and allele typing information in the picture by OCR technology configured to prioritize identification of picture formats for left-column loci and right-column alleles; And outputting the identification result, and supporting the secondary editing and storage of the identification result.
3. The DNA multidimensional affinity finding system of claim 1, wherein the hierarchy of the multidimensional affinity computation module for affinity computation comprises: the first-level kindred diad refers to the direct parent-child relationship between parents and children; The second-level kinship comprises a full sibling relationship and a ancestor-child relationship; The three-level relatives include a representative hall sibling and a second representative hall sibling.
4. The DNA multidimensional affinity finding system of claim 1, wherein the standardized authoritative algorithm in the multidimensional affinity computation module specifically comprises: The first-level genetic second conjunct is calculated by adopting GB/T37223-2018 technical Specification for paternity test; The isotactic cell relationship in the secondary genetic relationship is judged by IBS index and/or CFSI index by adopting SF/T0117-2021 biological isotactic cell relationship identification technical specification; The ancestor-child relationship in the second-level kinship carries out the kinship probability calculation through the CHS index; calculating the chance of the blood relationship by adopting an ITO method according to the first-class and second-class representative brothers of the third-class relatives; the isotype alignment adopts SF/Z JD0105012-2018 individual identification technical Specification to calculate the TDP index.
5. The DNA multidimensional affinity finding system of claim 1, wherein the multidimensional affinity calculation module is configured with mutation site processing logic when performing affinity calculations; The mutation site processing logic specifically comprises a likelihood calculation process for sites which do not accord with Mendelian's genetic law and have a mutation range of less than 3.
6. The DNA multidimensional intelligent tracking system according to claim 1, wherein the result output and ranking module is further configured to: Thickening and marking the comparison result which is in the relationship and meets the preset condition; Responding to double-click operation of a user on an analysis result, and displaying comparison details, wherein the comparison details comprise the genotyping, the paternity index and the non-father exclusion rate of each locus; And copying the analysis result to an Excel file for secondary treatment.
7. The DNA multidimensional intelligent tracking system according to claim 1, wherein the manual entry in the multimodal data import module supports user editing of loci and corresponding allelic typing and addition or deletion of locus entries.
8. A DNA multidimensional intelligent matching pursuit method applied to the DNA multidimensional intelligent matching pursuit system as claimed in any one of claims 1 to 7, comprising the steps of: s1, creating a case file, wherein the case file comprises a case number, a case name and a receiving date; s2, calling a multi-mode data import module to import DNA-STR data, wherein the import mode of the multi-mode data import module comprises CODIS file import, manual import and picture identification import; s3, creating a target crowd library, and storing DNA-STR data of the target crowd into the target crowd library; S4, according to target crowd library and the material to be analyzed selected from the case files by the user, invoking a preset standardized authority algorithm to operate the affinity, wherein the affinity comprises primary affinity two-body, secondary affinity and tertiary affinity calculation and homotypic comparison; s5, outputting analysis results containing the genetic index, and intelligently sequencing the analysis results according to the sequence from high to low of the genetic index values.
9. A computer-readable storage medium, on which a computer program is stored, characterized in that the program, when being executed by a processor, implements the DNA multidimensional intelligent tracking method according to claim 8.
10. An electronic device comprising a memory, a processor and a computer program stored on the memory and executable on the processor, wherein the processor implements the DNA multidimensional affinity finding method of claim 8 when the program is executed by the processor.

Description

DNA multidimensional genetic intelligent matching pursuit system, method, storage medium and electronic equipment Technical Field The invention relates to the technical field of genetic relationship identification, in particular to a DNA multidimensional genetic intelligent matching pursuit system, a method, a storage medium and electronic equipment. Background In the criminal investigation case detection field, a DNA-STR typing technology is used as a core technical means of identity recognition and affinity judgment, and with the continuous development of the technology, conventional work techniques of YSTR family tracing and constant STR affinity comparison are gradually formed in the industry. In order to standardize and guide the related identification work, the national and industry layers go out of a plurality of authoritative technical standards including SF/Z JD0105012-2018 individual identification technical specification and GB/T37223-2018 paternity identification technical specification, and a solid theoretical basis and operation standard support are provided for DNA paternity identification. However, with the deep criminal investigation, the need for DNA genetic comparison is gradually raised, and the method is not limited to the judgment of primary parent-child relations, but is further extended to cover more complex collateral parent relations such as secondary parent relations and tertiary parent relations. In face of the increasing complex scene comparison demands, the traditional technical means are not attractive, and a novel tool capable of realizing intelligent and full-dimensional genetic comparison is needed in the industry to fill the technical blank. In the prior art, the prior tool has the obvious technical defects that firstly, in terms of calculation efficiency, the prior tool highly depends on manual auxiliary processing data, and batch rapid comparison of massive normal STR data cannot be realized, so that the workload is large, the time is long, human errors are easy to occur, and the timeliness of cue acquisition is seriously affected. Secondly, in the genetic coverage range, the prior art can only complete partial type genetic relationship calculation, lacks the full coverage capability of primary to tertiary full-lineage genetic relationships, is difficult to meet the comparison requirements of complex family scenes such as grandchild, nephew, brothers and the like, and is extremely easy to cause clue omission. Furthermore, the processing logic of the mutation sites is not strict enough, the sites which do not accord with Mendelian's genetic law are usually directly removed in the prior art, and the sites below the mutation range 3 are not included in likelihood ratio calculation, so that the processing mode is caused by losing effective related clues due to neglecting slight genetic mutation, and the integrity of comparison is reduced. In addition, the single data import mode is also a big pain point, and the existing system only supports CODIS file import and manual input, can not analyze the common picture DNA data display format in criminal investigation work, is difficult to adapt to diversified data archiving forms, and improves the operation threshold of data warehousing. Finally, the degree of algorithm standardization is insufficient, part of calculation logic lacks unified authority algorithm support, and unified locus frequency data is not adopted, so that accuracy and traceability of calculation results are to be improved, and absolute and reliable technical basis cannot be provided for case detection. Disclosure of Invention The invention aims to provide a DNA multidimensional intelligent matching pursuit system, a method, a storage medium and electronic equipment, and realizes the multidimensional intelligent matching pursuit of a case material evidence detection material and the intelligent sequencing of results by multi-mode data import, target crowd library construction and multidimensional full-lineage genetic calculation. In order to achieve the above purpose, the present invention provides the following technical solutions: A DNA multidimensional affinity intelligence tracking system comprising: the case management module is used for creating a case file, wherein the case file comprises a case number, a case name and a receiving date; The multi-mode data import module is used for providing an input interface of DNA-STR data, and the import mode of the multi-mode data import module comprises CODIS file import, manual input and picture identification import; the target crowd library construction module is used for creating a target crowd library and storing DNA-STR data of a target crowd into the target crowd library by calling the multi-mode data import module; The multi-dimensional affinity calculation module is used for calling a preset standardized authority algorithm to calculate the affinity according to a target crowd library and the material to be