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CN-122025517-A - Manufacturing method of stable traditional internal liquid filling lithium electrode

CN122025517ACN 122025517 ACN122025517 ACN 122025517ACN-122025517-A

Abstract

The invention relates to a stable traditional internal liquid filling lithium electrode manufacturing method which comprises the following steps of 1, preparing a membrane solution, namely mixing 1.0-10wt% of lithium ion carrier, 50-70wt% of plasticizer, 25-35wt% of polymer, 0.05-1.5wt% of ion exchanger and 0.01-0.1wt% of stabilizer, fully stirring and dissolving the mixture by using an organic solvent, performing ultrasonic treatment to obtain uniformly dispersed electrode membrane solution, 2, performing membrane dripping membrane forming, namely dripping the membrane solution obtained in the step 1 into a special electrode shell by using a sample injection needle, drying to form an electrode membrane, and 3, performing electrode assembly, namely adding internal liquid into the electrode shell, and then assembling a fitting to obtain a complete electrode. The invention has the beneficial effects that the electrode performance is more stable, the service life is longer and the use cost is lower through optimizing the electrode film.

Inventors

  • LI WEILI
  • HUANG YANNI
  • WU BIN

Assignees

  • 桂林优利特医疗电子有限公司

Dates

Publication Date
20260512
Application Date
20260203

Claims (10)

  1. 1. A method for manufacturing a stable conventional internal liquid filled lithium electrode, comprising the steps of: Step 1, preparing a membrane liquid, namely mixing 1.0-10wt% of lithium ion carrier, 50-70wt% of plasticizer, 25-35wt% of polymer, 0.05-1.5wt% of ion exchanger and 0.01-0.1wt% of stabilizer, fully stirring, dissolving and performing ultrasonic treatment by using an organic solvent to obtain a uniformly dispersed electrode membrane liquid; step2, film dropping and forming, namely dropping the film obtained in the step1 into a special electrode shell through a sample adding needle, and drying to form an electrode film; And step 3, assembling the electrode, namely adding an internal liquid into the electrode shell, and then assembling the accessory to obtain the complete electrode.
  2. 2. The method for manufacturing a stable conventional internal liquid filled lithium electrode according to claim 1, wherein the lithium ion carrier in step 1 comprises crown ethers, open chain amides, 1,10 o-phenanthroline derivatives or tetraphenylborates, and the content thereof is 1.5wt% to 2.5wt%.
  3. 3. The method for manufacturing a stable conventional internal liquid filled lithium electrode according to claim 1, wherein the plasticizer in step 1 is one or more of 2-nitrophenyl octyl ether, bis (2-ethylhexyl) sebacate, bis (1-butyl amyl) adipate and dioctyl sebacate, and the content thereof is 60.0wt% to 70.0wt%.
  4. 4. The method for manufacturing a stable conventional internal liquid filled lithium electrode according to claim 1, wherein the polymer in the step 1 is one or more of polyvinyl chloride, polyurethane and epoxy resin, and the content thereof is 30-35 wt%.
  5. 5. The method for manufacturing a stable conventional internal liquid filled lithium electrode according to claim 1, wherein the ion exchanger in step 1 is one or more of potassium tetra (4-chlorophenyl) borate, tetradecylammonium tetra (4-chlorophenyl) borate and potassium tetra [3, 5-bis (trifluoromethyl) phenyl ] borate, and the content thereof is 0.25wt% to 0.5wt%.
  6. 6. The method for manufacturing a stable conventional internal liquid filled lithium electrode according to claim 1, wherein the stabilizer in step 1 is one or more of graphite, carbon black and carbon powder, and the content thereof is 0.01wt% to 0.05wt%.
  7. 7. The method for manufacturing a stable conventional internal liquid filled lithium electrode according to claim 1, wherein the organic solvent in step 1 is one or more of acetone, dichloromethane, chloroform and tetrahydrofuran.
  8. 8. The method for manufacturing a stable and traditional internal liquid filled lithium electrode according to claim 1, wherein the organic solvent in the step 1 is a mixed solvent of dichloromethane and trichloromethane, the mass ratio of the dichloromethane to the mixed solvent is 3:1, and the ultrasonic treatment time in the step 1 is 30min.
  9. 9. The method of claim 1, wherein the internal liquid is 50mmol/L HEPES buffer system, 4mmol/L KCl, 137mmol/L NaCl, 2.5mmol/L CaCl 2 and 0.5% Prclin preservative.
  10. 10. The method according to any one of claims 1 to 9, wherein the film is added dropwise in an amount of 20 μl to 150 μl in step 2, and dried for 12 hours in a ventilation environment at a temperature of <35 ℃ and a humidity of < 45.0%.

Description

Manufacturing method of stable traditional internal liquid filling lithium electrode Technical Field The invention relates to the field of medical inspection, in particular to a method for manufacturing a stable traditional internal liquid filling lithium electrode. Background The lithium carbonate is mainly used for treating mania, because the treatment concentration and poisoning concentration are relatively close, the Li ion concentration in serum of a patient is possibly toxic and causes life danger when being higher than 1.5mmol/L, therefore, the lithium electrode used by an electrolyte analyzer is required to be relatively stable when the Li ion concentration in serum is required to be accurately detected, an electrode film is a key point of electrode stability, the known liquid film electrode (classical electrode) is prepared by dissolving an ion selective carrier, a polymer, a plasticizer, an ion exchanger and the like in Tetrahydrofuran (THF), an elastic transparent film is obtained after THF is volatilized, the transparent film is commonly used for clinically detecting the problems that the ion exchanger is hydrolyzed and invalid in the use process, the carrier is lost and the like, the membrane body of the classical electrode film is aged and the service life of the electrode is short when the PVC film is soaked in acid-base and high-concentration ion solution for a long time, a new electrode is required to be frequently replaced, the all-solid state electrode is prepared by coating a carbon rod or metal wire (such as glass carbon rod and graphite rod) with an organic sensitive solution for preparing the PVC electrode, the poor stability of the electrode is slightly improved, the reproducibility of the electrode film is slightly improved, and the electrode film performance is prevented from being influenced by the solid state signal conducting and the solid electrolyte is prevented from being influenced by the solid state electrode layers (such as the solid state electrode is not being formed between the solid oxide film and the solid oxide film is not influenced by the surface layer). Disclosure of Invention In summary, in order to solve the technical problems of the classical electrode that the electrode performance is reduced, the signals are unstable and the electrode replacement frequency is high due to the aging of the membrane body, the technical problem of the invention is to provide a stable traditional internal liquid filled lithium electrode manufacturing method, which is found by experimental research, a small amount of stabilizer (carbon materials such as graphite, carbon powder, carbon black and the like) is mixed in the electrode membrane, and the electrode membrane prepared after strict environmental control is resistant to mechanical scouring, acid-base resistant and long in service life. The technical scheme for solving the technical problems is as follows, the stable traditional internal liquid filling lithium electrode manufacturing method comprises the following steps: Step 1, preparing a membrane liquid, namely mixing 1.0-10wt% of lithium ion carrier, 50-70wt% of plasticizer, 25-35wt% of polymer, 0.05-1.5wt% of ion exchanger and 0.01-0.1wt% of stabilizer, fully stirring, dissolving and performing ultrasonic treatment by using an organic solvent to obtain a uniformly dispersed electrode membrane liquid; step2, film dropping and forming, namely dropping the film obtained in the step1 into a special electrode shell through a sample adding needle, and drying to form an electrode film; And step 3, assembling the electrode, namely adding an internal liquid into the electrode shell, and then assembling the accessory to obtain the complete electrode. Based on the technical scheme, the invention can be further improved as follows: further, the lithium ion carrier in the step 1 comprises crown ethers, open chain amides, 1,10 phenanthroline derivatives or tetraphenylborate, and the content of the lithium ion carrier is 1.5-2.5 wt%. Further, the plasticizer in the step 1 is one or more of 2-nitrooctyl ether, bis (2-ethylhexyl) sebacate, bis (1-butyl amyl) adipate and dioctyl sebacate, and the content of the plasticizer is 60.0-70.0 wt%. Further, the polymer in the step 1 is one or more of polyvinyl chloride, polyurethane and epoxy resin, and the content of the polymer is 30-35 wt%. Further, the ion exchanger in the step 1 is one or more of potassium tetra (4-chlorophenyl) borate, tetradecyl ammonium tetra (4-chlorophenyl) borate and potassium tetra [3, 5-bis (trifluoromethyl) phenyl ] borate, and the content of the ion exchanger is 0.25-0.5 wt%. Further, the stabilizer in the step 1 is one or more of graphite, carbon black and carbon powder, and the content of the stabilizer is 0.01-0.05 wt%. Further, the organic solvent in the step 1 is one or more of acetone, dichloromethane, chloroform and tetrahydrofuran. Further, the organic solvent in the step 1 is a mixed solvent of dichlorometha