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CN-122028800-A - Method for preparing edible, malleable and palatable substrates for animals and use of such substrates

CN122028800ACN 122028800 ACN122028800 ACN 122028800ACN-122028800-A

Abstract

The present invention relates to a method of preparing an edible, malleable and palatable base for animals, comprising the steps of (i) providing a plurality of ingredients comprising at least one animal meal, starch and glycerin, said animal meal having a protein content higher than 60%, expressed by weight of dry matter relative to the total weight of dry meal, (ii) mixing said plurality of ingredients to obtain a formulation, (iii) optionally heating said formulation to a temperature ranging from about 60 ℃ to about 120 ℃, iv) obtaining said edible, malleable and palatable base.

Inventors

  • BIRCAN ERDEM
  • L. Berio

Assignees

  • 维丁诺夫制造公司

Dates

Publication Date
20260512
Application Date
20240813
Priority Date
20230817

Claims (11)

  1. 1. A method of preparing an edible, malleable and palatable base for an animal comprising the steps of: (i) Providing a plurality of ingredients comprising at least one animal meal, starch and glycerin, the animal meal having a protein content of greater than 60%, the% expressed by weight of dry matter relative to the total weight of the dry meal, (Ii) The various ingredients are mixed to obtain a formulation, (Iii) Optionally, heating the formulation to a temperature in the range of about 60 ℃ to about 120 ℃, (Iv) The edible, malleable and palatable base is obtained.
  2. 2. The method according to claim 1, characterized in that: the meal is selected from the group consisting of poultry meal, swine meal, fish meal, and mixtures thereof, and/or -The starch is rice starch.
  3. 3. The method according to claim 1 or 2, characterized in that: The meal is present in the formulation in an amount ranging from about 5% to about 60% by weight of raw materials relative to the total weight of the formulation, and/or Starch is present in the formulation in an amount ranging from about 2% to about 8% by weight of raw materials relative to the total weight of the formulation, and/or -Glycerol is present in the formulation in a content ranging from about 1% to about 14% by weight of raw materials relative to the total weight of the formulation.
  4. 4. A method according to any one of claims 1 to 3, characterized in that the edible, malleable and palatable matrix has an elasticity ranging from 0.25 to 0.50 and/or a cohesion ranging from 0.10 to 0.20, each measured according to standard texture analysis protocol (TPA).
  5. 5. The method according to any one of claims 1 to 4, characterized in that the edible, malleable and palatable base is palatable to domestic animals.
  6. 6. The method according to claim 5, characterized in that the edible, malleable and palatable base is palatable to dogs and/or cats.
  7. 7. An edible, malleable and palatable substrate obtainable by the method according to any one of claims 1 to 6.
  8. 8. A method of preparing a palatable carrier for an active intended for administration to an animal comprising the steps of: (i) Providing a plurality of ingredients comprising at least one animal meal, starch and glycerin, the animal meal having a protein content of greater than 60%, the% expressed by weight relative to the total weight of the meal, (Ii) The various ingredients are mixed to obtain a formulation, (Iii) Optionally heating the formulation to a temperature in the range of about 60 ℃ to about 120 ℃ to obtain an edible, malleable and palatable base for the animal, (Iv) Optionally cooling the matrix thus obtained, and (V) The palatable carrier is obtained by shaping the matrix from step (iii) or (iv) to render it in a form suitable for administration of the active substance to the animal.
  9. 9. A palatable carrier obtainable by the method of claim 8.
  10. 10. A method of conditioning an active intended for administration to an animal using a palatable carrier obtainable by the method of claim 8, comprising the steps of: a) Optionally opened, preferably by tearing, the edible, malleable and palatable base, B) Incorporating the active substance into the matrix, and C) Optionally, at least partially covering the active substance with the matrix.
  11. 11. Use of a palatable carrier obtainable by the process of claim 8 for administering at least one active substance to an animal.

Description

Method for preparing edible, malleable and palatable substrates for animals and use of such substrates Technical Field The present invention relates to a method of preparing an edible, malleable and palatable (palatable) base. The matrix is used to prepare a palatable carrier for administering an active agent to an animal. Background Oral administration of active substances, particularly pharmaceuticals, to animals is often difficult due to the unpleasant taste of some of these substances and the highly developed smell and taste of the animals. If absorption is denied, the chance of success of veterinary treatment may drop dramatically. Thus, there is a need for a package of active substances that can hinder the alertness of animals, particularly dogs, cats, horses, pigs, and ruminants. Today, many palatable carriers are known that allow the administration of active substances to animals. In particular, from EP 0 320 320a tablet is known which comprises a core containing an active substance and a palatable base completely covering the core. However, it is not feasible to individually and temporarily coat a drug that is delivered without a palatable base. From EP 0 574 301 a lozenge made of a matrix of a palatable material is known comprising a cavity having a shape substantially complementary to the shape of the tablet to be administered to the dog. However, such lozenges are inextensible and therefore the tablet must be pressed into the cavity. Therefore, it is not suitable for all tablet shapes and it is not possible to insert several tablets of the same size at the same time nor to insert active substances in the form of liquid or powder capsules therein. A palatable carrier for animal active substances, in particular for pharmaceutical products, is known from EP 1 562 549. The matrix of the carrier comprises at least one tacky surface having sufficient tackiness to bind the active substance by simple contact of the active substance with the tacky surface. There are many such vectors on the market today, such as the PILL ASSIST product sold under the brand Royal Canin (by MARS company in europe, especially GB, FR, DE) or the hill Pocket TM product sold under the brand Greenies TM (manufactured by Greenies company in the united states, manufactured by MARS PETCARE USA). This type of carrier is more advantageous because it allows the active substance, in particular the drug, to be immobilized by simply bringing it into contact with the adhesive surface of the matrix. No complex coating process is required. In addition, the adhesive fixation allows the carrier according to the invention to be used for active substances, for example prepared in the form of pills, tablets, capsules or powders, having any shape, for example substantially cylindrical, spherical or disk-shaped. However, not all of these products are equally easy to use. Because of their method of preparation, they have different textures and some are less extensible, less tacky or easily broken. Thus, coating certain types of active substances can be particularly difficult. These treatment difficulties directly affect the absorption of the active substance by the animal and ultimately the chance of success of the veterinary treatment. Thus, there is a need to develop new palatable carriers that are easier for the user to handle. Surprisingly, the inventors were able to demonstrate that by selecting animal meal powders (ANIMAL MEALS, animal meals, animal powders) with a protein content of higher than 60%, edible, malleable and palatable matrices with improved texture characteristics can be prepared, which not only facilitates coating of the active substances, but also their administration to animals. Disclosure of Invention The present invention relates to a method of preparing an edible, malleable and palatable base for animals. The invention also relates to an edible, malleable and palatable substrate obtainable by the above method. The invention also relates to a method of preparing a palatable carrier for an active intended for administration to animals. The invention also relates to a palatable carrier obtainable by the above process. The present invention relates to a kit and the use of a product as subject of the invention. The invention finally relates to a method for conditioning (conditioning) active substances intended for administration to animals by means of a palatable carrier, possibly obtained by means of the method of the invention. Drawings Fig. 1 shows the results of a cohesion test to evaluate the ability of a carrier according to the invention and its competitors to maintain their integrity during handling. Detailed Description The term "about" or "approximately" refers to a normal error range for a given value or range known to those skilled in the art. It generally means plus or minus 20%, for example plus or minus 10%, or plus or minus 5%, or even plus or minus 1% of a given value or range. "Greater" means strictly greater