CN-122028841-A - Multispectral photoacoustic apparatus

Abstract

An apparatus may include a platen, a light source system configured to provide first light of a first wavelength and second light of a second wavelength to a target object along a first axis, an ultrasonic receiver system, and a control system. The control system may be configured to cause the light source system to provide a first light to the target object at a first time and a second light to the target object at a second time, receive a first ultrasound receiver signal and a second ultrasound receiver signal from the ultrasound receiver system corresponding to photoacoustic responses of the target object to the first light and the second light, respectively, and estimate one or more vascular features based on at least one of the first ultrasound receiver signal or the second ultrasound receiver signal.

Inventors

• s. Agarwal
• Y.Zhan
• E. K. Brooks
• H. V. Panchavach
• LOPEZ ANTHONY
• N. Bakken
• K.D. Jorgef
• J.K. Schneider

Assignees

• 高通股份有限公司

Dates

Publication Date

20260512

Application Date

20240904

Priority Date

20230905

Claims (20)

1. 1. An apparatus, the apparatus comprising: A pressing plate; A light source system configured to provide light to a target object on an outer surface of the platen, the light including at least a first light of a first wavelength emitted by a first light emitting device and a second light of a second wavelength emitted by a second light emitting device, the light source system configured to provide the first light to the target object along a first axis and configured to provide the second light to the target object along the first axis; An ultrasonic receiver system configured to receive ultrasonic waves generated by the target object in response to the light from the light source system, and A control system configured to: causing the light source system to provide the first light to the target object at a first time; Receiving a first ultrasonic receiver signal from the ultrasonic receiver system corresponding to a photoacoustic response of the target object to the first light; causing the light source system to provide the second light to the target object at a second time; Receiving a second ultrasonic receiver signal from the ultrasonic receiver system corresponding to a photoacoustic response of the target object to the second light, and One or more vascular features are estimated based on at least one of the first ultrasound receiver signal or the second ultrasound receiver signal.
2. 2. The apparatus of claim 1, wherein the control system is further configured to distinguish a desired signal from one or more background signals based at least in part on the first ultrasonic receiver signal and the second ultrasonic receiver signal.
3. 3. The apparatus of claim 2, wherein the desired signal corresponds to a blood vessel within the target object.
4. 4. The device of claim 1, wherein the one or more vascular features comprise a vascular diameter, a vascular area, a vascular profile, a vasodilation, a volume flow, a pulse wave velocity, a vascular wall thickness, or a combination thereof.
5. 5. The apparatus of claim 1, wherein the control system is further configured to estimate blood pressure based at least in part on the one or more vascular features.
6. 6. The apparatus of claim 1, wherein the first light emitting device comprises a first laser configured to emit the first light, and wherein the second light emitting device comprises a second laser configured to emit the second light.
7. 7. The apparatus of claim 1, wherein the light source system further comprises a light guide system configured to convey light from the light source system to the platen.
8. 8. The device of claim 7, wherein a first light guide portion of the light guide system resides between at least two ultrasound receiver system portions.
9. 9. The apparatus of claim 8, wherein the light guide system comprises a second light guide portion configured to convey the first light to the first light guide portion and a third light guide portion configured to convey the second light to the first light guide portion.
10. 10. The device of claim 7, wherein at least a portion of the ultrasound receiver system is arranged as a ring around the first light guide portion.
11. 11. The apparatus of claim 7, wherein the light guide system comprises a first light guiding device and a second light guiding device configured to reflect light emitted by the second light emitting device towards the first light guiding device.
12. 12. The apparatus of claim 11, wherein the first light directing device is configured to direct light emitted by the first light emitting device and the second light emitting device along the first axis.
13. 13. The apparatus of claim 12, wherein the first axis is orthogonal or substantially orthogonal to a plane of the platen.
14. 14. The apparatus of claim 11, wherein the first light directing device comprises a mirror and the second light directing device comprises a beam splitter.
15. 15. The apparatus of claim 1, wherein the first axis is offset relative to a linear array of ultrasonic receiver elements at an angle in the range of 10 degrees to 60 degrees to a normal to a plane of the platen.
16. 16. The apparatus of claim 15, wherein the plane corresponds to an outer surface of the platen.
17. 17. The device of claim 1, wherein the ultrasound receiver system comprises a linear array of ultrasound receiver elements, a two-dimensional array of ultrasound receiver elements, or both.
18. 18. The device of claim 1, wherein the ultrasound receiver system comprises an array of transparent ultrasound receiver elements, a transparent piezoelectric layer, a transparent electrode layer, or a combination thereof.
19. 19. The apparatus of claim 1, wherein the ultrasound receiver system receives an acoustic wave from the target object along a second axis different from the first axis, the acoustic wave corresponding to the first ultrasound receiver signal and the second ultrasound receiver signal.
20. 20. The device of claim 19, wherein the second axis is separated from the first axis by an angle in the range of 10 degrees to 60 degrees.

Description

Multispectral photoacoustic apparatus Priority statement The present application claims priority from U.S. patent application Ser. No. 18/461,397, entitled "MULTISPECTRAL PHOTOACOUSTIC DEVICES (multispectral photoacoustic device)" filed on month 9 of 2023, which is hereby incorporated by reference for all purposes. Technical Field The present disclosure relates generally to photoacoustic devices and systems. Description of related Art Various sensing techniques and algorithms are being implemented in devices for a variety of biological and biomedical applications, including health and wellness monitoring. This push is due in part to the limitations of the availability of conventional measurement devices for continuous, non-invasive and ambulatory monitoring. Some such devices are or include photoacoustic devices. While some previously deployed photoacoustic devices and systems may provide acceptable results, improved photoacoustic devices and systems would be desirable. Disclosure of Invention The systems, methods, and devices of the present disclosure each have several aspects, no single one of which is solely responsible for the desirable attributes disclosed herein. One innovative aspect of the subject matter described in this disclosure can be implemented in an apparatus. In some implementations, a mobile device (such as a wearable device, a cellular telephone, etc.) may be or include at least a portion of the apparatus. The apparatus may include a platen, a light source system, and a receiver system. The receiver system may be or include an ultrasound receiver system configured to receive ultrasound generated by the target object in response to the light from the light source system. According to some examples, the light source system may be configured to provide light to a target object on an outer surface of the platen. In some examples, the light may include at least a first light of a first wavelength (such as light having an amplitude peak at the first wavelength) and a second light of a second wavelength (such as light having an amplitude peak at the second wavelength). In some implementations, the apparatus may include a control system. The control system may include one or more general purpose single or multi-chip processors, digital Signal Processors (DSPs), application Specific Integrated Circuits (ASICs), field Programmable Gate Arrays (FPGAs) or other programmable logic devices, discrete gate or transistor logic, discrete hardware components, or a combination thereof. The control system may be configured to cause the light source system to provide a first light to the target object at a first time, receive a first ultrasonic receiver signal from the ultrasonic receiver system corresponding to a photoacoustic response of the target object to the first light, cause the light source system to provide a second light to the target object at a second time, receive a second ultrasonic receiver signal from the ultrasonic receiver system corresponding to a photoacoustic response of the target object to the second light, and distinguish the desired signal from the one or more background signals based at least in part on the first ultrasonic receiver signal and the second ultrasonic receiver signal. According to some implementations, the apparatus may include a platen and a light source system configured to provide light to a target object on an outer surface of the platen, the light including at least a first light of a first wavelength emitted by a first light emitting device and a second light of a second wavelength emitted by a second light emitting device. In some examples, the light source system may be configured to provide the first light to the target object along a first axis, and may be configured to provide the second light to the target object along the first axis. According to some implementations, the apparatus may include an ultrasound receiver system configured to receive ultrasound generated by the target object in response to the light from the light source system, and a control system configured to cause the light source system to provide first light to the target object at a first time, receive a first ultrasound receiver signal from the ultrasound receiver system corresponding to a photoacoustic response of the target object to the first light, cause the light source system to provide second light to the target object at a second time, receive a second ultrasound receiver signal from the ultrasound receiver system corresponding to a photoacoustic response of the target object to the second light, and estimate one or more vascular features based on at least one of the first ultrasound receiver signal or the second ultrasound receiver signal. In some implementations, the apparatus may include a platen and a light source system configured to provide light to a target object on an outer surface of the platen, the light including at least a first light of a first wavelength emitted by