CN-122028847-A - Monitoring window based on chemical information

CN122028847ACN 122028847 ACN122028847 ACN 122028847ACN-122028847-A

Abstract

Systems and methods are disclosed that trigger a diuretic monitoring window, including determining a health index of a patient as a function of received physiological information, determining a health index alarm state of the patient using a value of the determined health index and a health index alarm threshold, monitoring the health index in the health index alarm state, triggering a start of the diuretic monitoring window in response to a detected change in the health index alarm state indicating an improved patient condition, receiving chemical information of the patient during the diuretic monitoring window, and monitoring a chemical parameter of the patient during the diuretic monitoring window using the received chemical information.

Inventors

Victoria A. Averina
LI YINGBO
MICHAEL J. KANE
Pramodesinger Hirasinger Takur

Assignees

心脏起搏器股份公司

Dates

Publication Date: 20260512
Application Date: 20241125
Priority Date: 20231129

Claims (15)

1. A medical device system, comprising: A signal receiver circuit configured to receive physiological information of a patient, and An evaluation circuit configured to: determining a health index of the patient as a function of the received physiological information, Determining a health index alarm state of the patient using the determined value of the health index and a health index alarm threshold; Monitoring the health index in the health index alert state, and In response to detecting a change in the health index alert state indicating an improved patient condition, triggering the onset of a diuretic monitoring window, Wherein the signal receiver circuit is configured to receive chemical information of the patient during the urination monitoring window, Wherein the evaluation circuit is configured to monitor a chemical parameter of the patient during the diuretic monitoring window using the received chemical information.
2. The medical device system of claim 1, wherein the health index comprises a composite health index, wherein the evaluation circuit is configured to determine the composite health index of the patient as a function of at least two characteristics of the received physiological information.
3. The medical device system of any one of claims 1-2, wherein determining the health index alarm state of the patient includes determining that the health index of the patient is in an alarm state using the determined value of the health index and the health index being at an alarm threshold, Wherein monitoring the health index comprises monitoring the health index while the health index is in an alarm state, Wherein triggering the onset of the diuretic monitoring window includes indicating an improved patient condition in response to a change in a value of a health index detected while the health index is in an alert state toward the health index being at an alert threshold or the health index being off the alert threshold being greater than a first threshold.
4. The medical device system of any one of claims 1-3, wherein monitoring the patient's chemical parameter comprises determining a value of the patient's chemical parameter using the received chemical information, monitoring the determined chemical parameter during the diuretic monitoring window, and determining a chemical alarm state of the patient if the value of the determined chemical parameter exceeds a chemical alarm threshold in the diuretic monitoring window, Wherein the evaluation circuit is configured to provide an output of the determined chemical alarm state to a user interface for display to a user or to a control circuit to control or adjust a process or function of the medical device system.
5. The medical device system of claim 4, wherein the chemical alert threshold is determined as a function of a detected rate of change of a value of the determined chemical parameter in at least a portion of the urination monitoring window.
6. The medical device system of any one of claims 4-5, wherein the health index comprises a heart failure index, Wherein the chemical parameter or the chemical information comprises at least one of potassium information or creatinine information of the patient.
7. The medical device system of any one of claims 1-6, wherein the health index alarm state includes one of a health index in an alarm state and a health index out of an alarm state, Wherein the diuretic monitoring window includes an initial duration including a first period of time after a detected transition from the health index being in an alert state to the health index exiting the alert state.
8. The medical device system of claim 7, wherein the first period of time has an initial duration that includes a predefined number of days, the predefined number being between 3 days and 31 days.
9. The medical device system of any one of claims 7 to 8, wherein the evaluation circuit is configured to expand the duration of the urination monitoring window in response to the received chemical information crossing a first chemical alarm threshold during an initial duration of the urination monitoring window, Wherein the evaluation circuit is configured to end the duration of the extended diuretic monitoring window in response to the received chemical information crossing a second chemical alarm threshold during the duration of the extended diuretic monitoring window.
10. The medical device system of any one of claims 1 to 9, wherein monitoring the patient's chemical parameter comprises determining a value of the patient's chemical parameter using the received chemical information, monitoring the determined chemical parameter during the diuretic monitoring window, and determining a chemical alarm status of the patient if a rate of change of the determined value of the chemical parameter exceeds a chemical rate threshold in the diuretic monitoring window, Wherein the evaluation circuit is configured to provide an output of the determined chemical alarm state to a user interface for display to a user or to a control circuit to control or adjust a process or function of the medical device system.
11. The medical device system of any one of claims 1 to 10, wherein the alarm condition comprises one of an alarm condition and a disengaged alarm condition, Wherein the evaluation circuit is configured to trigger the start of the urination monitoring window in response to a detected transition from the in-alert state to the out-of-alert state.
12. A method, comprising: Receiving physiological information of a patient using a signal receiver circuit, and Using an evaluation circuit: determining a health index of the patient as a function of the received physiological information, Determining a health index alarm state of the patient using the determined value of the health index and a health index alarm threshold; Monitoring the health index in the health index alert state, and Triggering the onset of a diuretic monitoring window in response to a detected change in health index in the health index alert state indicating an improved patient condition; Receiving chemical information of the patient during the diuretic monitoring window using the signal receiver circuit, and Using the evaluation circuit, chemical parameters of the patient are monitored during the diuretic monitoring window using the received chemical information.
13. The method of claim 12, wherein determining the health index alarm state of the patient comprises determining that the health index of the patient is in an alarm state using the determined value of the health index and the health index being at an alarm threshold, Wherein monitoring the health index comprises monitoring the health index while the health index is in an alarm state, Wherein triggering the onset of the diuretic monitoring window includes indicating an improved patient condition in response to a change in a value of a health index detected while the health index is in an alert state toward the health index being at an alert threshold or the health index being off the alert threshold being greater than a first threshold.
14. The method of any one of claims 12 to 13, wherein monitoring the patient's chemical parameters comprises determining a value of the patient's chemical parameters using the received chemical information, monitoring the determined chemical parameters during the diuretic monitoring window, and determining a chemical alarm state of the patient if the value of the determined chemical parameters exceeds a chemical alarm threshold in the diuretic monitoring window, Wherein the evaluation circuit is configured to provide an output of the determined chemical alarm state to a user interface for display to a user or to a control circuit to control or adjust a process or function of the medical device system.
15. The method of claim 14, comprising determining the chemical alert threshold as a function of a detected rate of change of a value of a determined chemical parameter in at least a portion of the diuretic monitoring window, wherein the health index comprises a heart failure index, wherein the chemical parameter or the chemical information comprises at least one of potassium information or creatinine information of the patient.

Description

Monitoring window based on chemical information Priority claim The application claims the benefit of U.S. provisional application No. 63/604,089, filed on 11/29 of 2023, which is incorporated herein by reference in its entirety. Technical Field This document relates generally to medical devices and, more particularly, to monitoring chemical information after health index alarms. Background Ambulatory medical devices (Ambulatory MEDICAL DEVICE, AMD), including implantable, subcutaneous, wearable, or one or more other medical devices, etc., can monitor, detect, or treat a variety of conditions, including Heart Failure (HF), atrial fibrillation (atrial fibrillation, AF), etc. The ambulatory medical device can include a sensor that senses physiological information from the patient, and one or more circuits that detect one or more physiological events using the sensed physiological information or transmit the sensed physiological information or the detected physiological events to one or more remote devices. Frequent patient monitoring may provide early detection of worsening patient conditions, including worsening heart failure or atrial fibrillation. The accurate identification of patients or patient groups at high risk of future adverse events may control the mode or feature selection or resource management of one or more ambulatory medical devices, control notifications or messages in the connected system to various users associated with a particular patient or patient group, organize or schedule doctor or patient contact or treatment, or prevent or reduce patient hospitalization. The risk of worsening patient condition is properly identified and safely managed, avoiding unnecessary medical intervention, extending the life of ambulatory medical devices, and reducing medical care costs. Disclosure of Invention Systems and methods for monitoring a chemical state of a patient after a health index alert using one or more pieces of chemical information are disclosed. The chemical information may include one or more of potassium information, creatinine information, and the like. Additional alarms or signals may be provided to the user or process based on the monitored information. Examples of the subject matter (e.g., a medical device system) may include a signal receiver circuit configured to receive physiological information of a patient, and an evaluation circuit configured to determine a health index of the patient as a function of the received physiological information, determine a health index alarm state of the patient using a value of the determined health index and a health index alarm threshold, monitor the health index in the health index alarm state, and trigger a start of a diuresis monitoring window in response to a detected change in the health index alarm state indicating an improved patient condition, wherein the signal receiver circuit is configured to receive chemical information of the patient during the diuresis monitoring window, wherein the evaluation circuit is configured to monitor a chemical parameter of the patient during the diuresis monitoring window using the received chemical information. In an example, which may be combined with any one or more of the preceding examples, the health index includes a composite health index, wherein the evaluation circuit is configured to determine the composite health index of the patient as a function of at least two features of the received physiological information. In an example, which may be combined with any one or more of the preceding examples, determining a health index alarm state of the patient includes determining that the health index of the patient is in an alarm state using the determined value of the health index and the health index being at an alarm threshold, wherein monitoring the health index includes monitoring the health index while the health index is in the alarm state, wherein triggering the onset of the diuretic monitoring window includes indicating an improved patient condition in response to a change in the value of the health index detected while the health index is in the alarm condition toward the health index being at the alarm threshold or the health index being out of the alarm threshold being greater than a first threshold. In an example, which may be combined with any one or more of the preceding examples, monitoring the chemical parameter of the patient includes determining a value of the chemical parameter of the patient using the received chemical information, monitoring the determined chemical parameter during a urination monitoring window, and determining a chemical alarm state of the patient if the value of the determined chemical parameter exceeds a chemical alarm threshold in the urination monitoring window, wherein the evaluation circuit is configured to provide an output of the determined chemical alarm state to a user interface for display to a user, or to a control circuit for controlling or adjusting a