CN-122028884-A - Device for visualizing and treating eye diseases

Abstract

A patient interface device may be secured to an eye of a patient to interface the eye with respect to an imaging and/or laser treatment system. The patient interface may include one or more actuators capable of perturbing the eye to impart motion to mosquitoes in the eye. The movement of the mosquito may be used to move the mosquito to an area in the eye that is more conducive to visualizing, imaging, and/or treating the mosquito. Furthermore, a fixation target is described that can facilitate a patient's visualization of a particular mosquito and correlate that particular mosquito with the mosquito being imaged.

Inventors

• M. BROWNELL
• C. Cherokee
• N. Kaczynski
• K. BELL
• W. Stolt
• L. Gomez

Assignees

• 脉冲医疗公司

Dates

Publication Date

20260512

Application Date

20240726

Priority Date

20230728

Claims (20)

1. 1. A removable patient interface device, comprising: an ocular interface comprising at least one optical element for interfacing with an eye of a patient; A movable portion secured to the ocular interface; part capable of being fixed to an imaging and treatment system, and At least one actuator coupled between the fixed portion and the movable portion, Wherein operation of the at least one actuator perturbs the patient's eye when the ocular interface is docked with the patient's eye.
2. 2. The removable patient interface device of claim 1, further comprising: At least one lens mount releasably receiving the lens component.
3. 3. The movable patient interface device according to claim 1 or 2, wherein the at least one actuator is capable of applying one or more of: Rotational disturbance; Vertical translational disturbance, and Horizontal translational disturbance.
4. 4. A removable patient interface device according to any one of claims 1 to 3, wherein the portion securable to an imaging and therapy system comprises an interface for coupling to the imaging and therapy system, the interface comprising: a portion of a mechanical interface that engages a corresponding portion of a mechanical interface of the imaging and therapy system; a portion of an optical interface optically coupled to a corresponding portion of an optical interface of the imaging and therapy system, and A portion of the electrical interface electrically coupled to a corresponding portion of the electrical interface of the imaging and therapy system.
5. 5. A removable patient interface device according to any one of claims 1 to 4, wherein the removable patient interface device is provided as a plurality of engageable components.
6. 6. The removable patient interface device according to claim 5, wherein the plurality of engageable members comprises: An eyelid retractor comprising at least one mating feature, and A housing for the ocular interface, the movable portion, the fixed portion, and the at least one actuator, the housing including at least one corresponding mating feature corresponding to at least one mating feature of the eyelid speculum to engage the eyelid speculum with the housing.
7. 7. The removable patient interface device according to claim 5, wherein the plurality of engageable members comprises: An eyelid retractor, comprising: at least one mating feature, and A docking collar, comprising: -an ocular interface; at least one corresponding mating feature corresponding to the at least one mating feature of the eyelid retractor to engage the eyelid retractor with the docking ring, and At least one housing mating feature, and -A housing for the movable portion, the fixed portion and the at least one actuator, the housing comprising at least one corresponding housing mating feature corresponding to at least one housing mating feature of the docking ring to engage the housing with the docking ring.
8. 8. The removable patient interface device according to claim 5, wherein the plurality of engageable members comprises: a docking collar, comprising: an adsorption ring for attaching the docking ring to the eye, and Eye interface, and At least one housing mating feature, and A housing for the movable portion, the stationary portion, and the at least one actuator, the housing including at least one corresponding housing mating feature corresponding to at least one housing mating feature of the docking collar to engage the housing with the docking collar.
9. 9. The removable patient interface device of claim 8, wherein the docking ring comprises: one or more vacuum ports fluidly coupled to the adsorption ring, and One or more liquid ports for allowing liquid or gel to be provided to a volume between the patient's eye and an interior portion of the docking ring.
10. 10. The removable patient interface device of claim 9, wherein the docking ring comprises a meniscus lens.
11. 11. The removable patient interface device according to claim 9, wherein the liquid port is disposed between the meniscus lens and the suction ring.
12. 12. A mobile patient interface device according to any one of claims 1-8, further comprising a controller for controlling at least the at least one actuator.
13. 13. A mobile patient interface device according to any one of claims 1-9, wherein the at least one actuator comprises at least one of: A motor; Magnetic actuator, and A piezoelectric actuator.
14. 14. The removable patient interface device according to any one of claims 1 to 10, further comprising: an inlet port for injecting fluid into a space between the patient's eye and the eye interface when docked with the patient's eye, and An outlet port arranged towards the top of the space to allow air and/or injection fluid to escape from the space.
15. 15. A docking ring securable to an eye of a patient, comprising: A docking surface for contacting a portion of the patient's eye; one or more vacuum ports fluidly coupled to an adsorptive ring contacting the patient's eye during use; one or more liquid ports fluidly coupled to a chamber defined between the patient's eye and an interior chamber of the docking ring, Wherein, in use, a vacuum is applied to the one or more vacuum ports to seal the docking ring to the patient's eye around the adsorption ring and supply liquid or gel to the chamber through the one or more liquid ports.
16. 16. The docking ring of claim 15, wherein the one or more vacuum ports comprise a plurality of vacuum ports.
17. 17. The docking ring of claim 15, wherein the one or more liquid ports comprise a plurality of liquid ports.
18. 18. The docking ring of any of claims 15 to 17, further comprising a meniscus lens defining at least a portion of an interior chamber of the docking ring.
19. 19. The docking ring of claim 18, wherein the one or more liquid ports are disposed between the one or more vacuum ports and the meniscus lens.
20. 20. A fixation target for visualizing mosquitoes, the fixation target comprising: A light source; a visualization guide comprising a visible marking on a substantially transparent surface; A housing accommodating the light source and the visual guide, and An optical input and output port disposed adjacent to the visualization guide.

Description

Device for visualizing and treating eye diseases RELATED APPLICATIONS The present application claims priority from U.S. provisional application serial No. 63/529,659, entitled "device for visualization and treatment of ocular diseases (Devices For Use In Visualization AND TREATMENT of Ocular Disorders)" filed on 7.28 of 2023, the entire contents of which are incorporated herein by reference in their entirety for all purposes. Technical Field The present disclosure relates to ophthalmic devices and methods, and in particular to devices for the treatment and visualization of vitreous mosquito disease, also known as symptomatic vitreous opacity (Symptomatic Vitreous Opacities, SVOs), and other ocular diseases. Background Laser treatment in the human eye may require precise imaging and laser targeting of the laser treated portion or structure of the eye. Imaging and laser targeting requires maintenance of the physical relationship between the imaging component, the treatment component, the patient and the eye in order to reliably image and laser target the eye treatment area. The patient interface device is a general solution for connecting and controlling the relative physical positioning of the patient, the eye, the imaging component and the laser treatment component. The patient interface device may interface with a patient's eye and be used to maintain a physical relationship between the eye and the imaging component and the laser treatment component. There are various patient interface devices, such as the LenSx: laser SoftFitTM patient interface manufactured by Alcon, or the CATALYSTM LIQUID OPTICS interface manufactured by Johnson & Johnson. The mosquito disease also has additional unique characteristics of individual turbulent motion within the vitreous body that can make visualization, imaging, tracking, and treatment of the mosquito disease difficult. Drawings Other features and advantages of the present disclosure will become apparent from the following detailed description, taken in conjunction with the accompanying drawings, in which: FIG. 1 illustrates a system for treating mosquito conditions using a removable patient interface device and a patient motion control device; FIG. 2 illustrates a movable patient interface device coupled to an imaging and therapy system; FIGS. 3A and 3B illustrate a removable patient interface device; FIG. 4 shows docking details of the removable patient interface device; FIG. 5 illustrates a front view of another embodiment of a docking assembly; FIG. 6 shows a right front perspective view of the docking assembly; FIG. 7 illustrates an eye cup of the docking assembly of FIG. 5; FIG. 8 shows a first cross-section of the eye cup of FIG. 7; FIG. 9 shows a second cross-section of the eye cup of FIG. 7; FIG. 10 illustrates a method of treating mosquito conditions using a removable patient interface device; FIG. 11 illustrates a method of calibrating the control motion of a mosquito; FIG. 12 shows an OCT image of bubbles formed during laser therapy; FIG. 13 illustrates a method for calibrating a therapeutic laser focal depth; FIG. 14 shows an OCT M scan of bubbles formed above a reference surface; FIG. 15A shows a calibration curve for depth of focus; FIG. 15B shows a calibration surface for depth of focus; FIG. 16 shows components of a fixation target for visualizing mosquitoes; Fig. 17 shows a fixation target for coupling to an imaging and therapy system, and Fig. 18 shows a view through a fixation target. Detailed Description In accordance with the present disclosure, a movable patient interface device is provided that includes an ocular interface including at least one optical element for interfacing with a patient's eye, a movable portion secured to the ocular interface, a portion securable to an imaging and therapy system, and at least one actuator coupled between the fixed portion and the movable portion, operation of the at least one actuator perturbing the patient's eye when the ocular interface interfaces with the patient's eye. In another embodiment of the removable patient interface device, the removable patient interface device further comprises at least one lens mount that releasably receives the lens component. In another embodiment of the movable patient interface device, wherein the at least one actuator may apply one or more of a rotational disturbance, a vertical translational disturbance, and a horizontal translational disturbance. In another embodiment of the removable patient interface device, the portion that can be secured to the imaging and therapy system includes an interface for coupling to the imaging and therapy system, the interface including a portion of a mechanical interface that engages a corresponding portion of the mechanical interface of the imaging and therapy system, a portion of an optical interface that is optically coupled to a corresponding portion of the optical interface of the imaging and therapy system, and a portion of an elec