CN-122029475-A - Astigmatic corrective contact lens with smooth edge, spherical and/or aspherical geometric design

Abstract

The present invention provides an axisymmetric soft contact lens having an aspherical and/or spherical geometry for correcting refractive errors of the eye.

Inventors

• ALSTER YAIR
• JAIN RACHNA
• O. Lafayette
• B. Azmon
• I. Svarfit Brand

Assignees

• 朱尼万股份有限公司

Dates

Publication Date

20260512

Application Date

20241007

Priority Date

20240304

Claims (20)

1. 1. A soft contact lens for correcting refractive errors of an eye, comprising: a soft continuous lens body configured to cover a corneal surface of an eye, having an anterior surface and a posterior surface, and Wherein the contact lens has a center thickness of between about 80 microns to about 350 microns, and Wherein the soft contact lens is axisymmetric; wherein the soft continuous lens body has at least a central aspheric portion and a peripheral aspheric portion; Wherein the central aspheric portion has a base arc at its center of less than 9mm and a base arc at its edge of less than 8mm, and Wherein the peripheral aspheric portion has a base arc at its proximal end of greater than 8mm and a base arc at its distal end of greater than 8.5 mm; wherein at least a portion of the rear surface of the flexible lens body is configured to suspend above a corneal surface of an eye when placed thereon, thereby forming a free volume between the rear surface of the flexible lens body and the corneal surface, and wherein at least a portion of the free volume is configured to be filled with tear fluid to form a tear lens on the corneal surface, thereby correcting refractive errors of the eye.
2. 2. A soft contact lens for correcting refractive errors of an eye, comprising: a soft continuous lens body configured to cover a corneal surface of an eye, having an anterior surface and a posterior surface, and Wherein the contact lens has a center thickness of between about 80 microns to about 350 microns, and Wherein the soft contact lens is axisymmetric; Wherein the soft lens body has at least a central aspheric portion and a peripheral spherical portion; Wherein the central aspheric portion has a base arc at its center of less than 9mm and a base arc at its edge of less than 8mm, and Wherein the peripheral spherical portion has a base arc of greater than 8.5 mm; wherein at least a portion of the rear surface of the flexible lens body is configured to suspend above a corneal surface of an eye when placed thereon, thereby forming a free volume between the rear surface of the flexible lens body and the corneal surface, and wherein at least a portion of the free volume is configured to be filled with tear fluid to form a tear lens on the corneal surface, thereby correcting refractive errors of the eye.
3. 3. A soft contact lens for correcting refractive errors of an eye, comprising: a soft continuous lens body configured to cover a corneal surface of an eye, having an anterior surface and a posterior surface, and Wherein the contact lens has a center thickness of between about 80 microns to about 350 microns, and Wherein the soft contact lens is axisymmetric; wherein the soft lens body has at least a central spherical portion and a peripheral aspherical portion; Wherein the base arc of the central spherical portion is less than 9mm, and Wherein the peripheral aspheric portion has a base arc at its proximal end of greater than 8mm and a base arc at its distal end of greater than 8.5 mm; wherein at least a portion of the rear surface of the flexible lens body is configured to suspend above a corneal surface of an eye when placed thereon, thereby forming a free volume between the rear surface of the flexible lens body and the corneal surface, and wherein at least a portion of the free volume is configured to be filled with tear fluid to form a tear lens on the corneal surface, thereby correcting refractive errors of the eye.
4. 4. A soft contact lens for correcting refractive errors of an eye, comprising: a soft continuous lens body configured to cover a corneal surface of an eye, having an anterior surface and a posterior surface, and Wherein the contact lens has a center thickness of between about 80 microns to about 350 microns, and Wherein the soft contact lens is axisymmetric; Wherein the soft lens body has at least a central spherical portion and a peripheral spherical portion; Wherein the base arc of the central spherical portion is less than 9mm, and Wherein the peripheral spherical portion has a base arc of greater than 9 mm; wherein at least a portion of the rear surface of the flexible lens body is configured to suspend above a corneal surface of an eye when placed thereon, thereby forming a free volume between the rear surface of the flexible lens body and the corneal surface, and wherein at least a portion of the free volume is configured to be filled with tear fluid to form a tear lens on the corneal surface, thereby correcting refractive errors of the eye.
5. 5. The soft contact lens of any one of claims 1-4, wherein the refractive error of the eye is selected from the group consisting of corneal irregularities, coma, astigmatism, higher order aberrations of the eye, and any combination thereof.
6. 6. The soft contact lens of any one of claims 1-5, wherein the soft lens body comprises at least one discrete discontinuity selected from a channel, an aperture, a groove, an opening, a slit, a thin portion, or any combination thereof.
7. 7. The soft contact lens of any one of claims 1-6 having a young's modulus <4 Mpa.
8. 8. The soft contact lens of claims 1-9, wherein the refractive error is astigmatism.
9. 9. The soft contact lens of claims 1-9, wherein the refractive error is an optical aberration of the eye.
10. 10. The soft contact lens of claim 6 wherein the discrete discontinuity is at least one aperture passing between the anterior surface and the posterior surface.
11. 11. The soft contact lens of any one of claims 1-10, wherein the soft lens body has an anterior surface, a posterior surface, and at least one aperture therethrough between the anterior surface and the posterior surface, wherein the at least one aperture is positioned adjacent to the lacrimal meniscus of the eye.
12. 12. The soft contact lens of claim 11, wherein the at least one aperture is configured to be positioned adjacent to a lacrimal meniscus of an eye to facilitate tear fluid flow therefrom to the free volume, from adjacent an anterior surface of the lens body to a posterior surface of the lens body and to the free volume.
13. 13. The soft contact lens of claim 12, wherein the lacrimal meniscus is one or more of an upper lacrimal meniscus and/or a lower lacrimal meniscus of an eye.
14. 14. The soft contact lens of claim 12, wherein the at least one aperture is configured to be positioned adjacent to a tear meniscus to facilitate tear flow to the free volume regardless of the orientation of the lens relative to the tear meniscus when the lens body is applied to the corneal surface when the eyelid of the eye is open.
15. 15. The soft contact lens of claim 12, wherein the at least one aperture is configured to be positioned adjacent to a tear meniscus to facilitate tear flow to a free volume.
16. 16. The soft contact lens of claim 12, wherein the at least one aperture is configured to be positioned adjacent to a tear meniscus a distance of about 0.0mm to about 4mm.
17. 17. The soft contact lens of claim 10 wherein the at least one aperture is located about 3mm to about 9mm from the center of the lens body.
18. 18. The soft contact lens of claim 10 comprising a plurality of openings.
19. 19. The soft contact lens of claim 18, wherein the plurality of openings are evenly distributed about the center of the soft lens body.
20. 20. The soft contact lens of claim 18, wherein the plurality of openings are unevenly distributed about the center of the soft lens body.

Description

Astigmatic corrective contact lens with smooth edge, spherical and/or aspherical geometric design Cross Reference to Related Applications The present application claims the benefit of U.S. application Ser. No. 63/588,645, filed on 6 at 10 at 2023, and/or U.S. application Ser. No. 63/560,974, filed on 4 at 3 at 2024, and/or U.S. application Ser. No. 63/574,027, filed on 3 at 4 at 2024, which are incorporated herein by reference in their entirety. Background Refractive errors are common eye conditions that occur when the shape of the eye prevents light from focusing directly on the back of the eye, resulting in blurred vision, as well as other symptoms. Ametropia includes astigmatism, myopia, and/or presbyopia. For those with one or more refractive errors, a more specialized contact lens with additional features and correction may be required to correct the one or more refractive errors. Astigmatism is a visual defect in the curvature of the eye that can lead to near-far vision blur. Astigmatism occurs when the cornea or lens has a non-matching curve (rather than a spherical curve, the surface changes its curvature like an egg shape). This can lead to blurred vision at all distances (normal, near or far vision). Such refractive errors may be corrected by eyeglasses, contact lenses and/or surgery. A person with an astigmatic cornea may need a contact lens that corrects for different refractive errors in at least two of the noons. In addition, those with such ametropia and using contact lenses may have many different spherical powers. The power at each noon, the angle of the particular meridian, and/or the diameter at which the power difference occurs typically varies from individual to individual. Because of the additional fitting criteria, a large number of specialized contact lenses meeting corrective criteria need to be manufactured and stored. Moreover, the fitting of these specialized contact lenses can be more time consuming than the fitting of conventional contact lenses. Furthermore, due to the complexity of refractive errors, current contact lenses may not be suitable for correcting one or more refractive errors with a high degree of satisfaction. Current treatments for such corneal irregularities with soft contact lenses involve contact lenses having multiple base curves and features that allow alignment and rotation to a wearer-specific astigmatism axis. Examples include structural elements such as prismatic drop and dynamic stabilization elements. These lenses, commonly referred to as toric lenses, typically require the manufacture of multiple lenses for each power difference and angle between meridians. It is generally assumed that opposite meridians have similar curvature and that deviations of +/-5 degrees are generally less pronounced. Thus, with an axial step of 10 degrees, each sphere (ranging from +6.0D to-6.0D in steps of 0.25D) and cylinder power combination (typically 0.75D to 2.5D relative to sphere) typically requires 18 lens steps to cover the various astigmatism that the patient may suffer from. This results in thousands of different lenses being produced. Accordingly, solutions are needed to minimize the number of different contact lenses that must be manufactured and stored. To address this challenge, a lens for astigmatism correction was developed. Regardless of its rotational state, the lens is designed to remain relatively flat on the flat meridian of the cornea and to arch on the steep meridian. Maintaining the spherical position of the soft contact lens above the aspherical cornea requires unobstructed fluid flow. While grooves may enhance fluid conductivity, considerations regarding geometry, base curve, transitions between base curves, profile, distribution and location of grooves and apertures are critical to maintaining and improving comfort and functionality of the lens. Accordingly, solutions are needed to reduce the number of different contact lenses that need to be manufactured and stored and to improve treatment options for astigmatic or other optical aberration patients. Disclosure of Invention The present invention is based on clinical evidence that two key elements, fluid exchange and acceptable lens geometry, are required to manufacture a lens that effectively masks astigmatism. It has been found that certain geometries allow optimal masking, while others are not. The lens requires at least one of a central portion that enables the lens structure to arch over certain portions of the cornea, and a peripheral portion that allows good exchange of fluid through the lens rim, and an outward discharge upon blinking and an inward inflow between blinks. Furthermore, it has been found that combining the geometry with features (e.g., openings) that enhance fluid entry under the lens and/or grooves on the posterior surface that enhance fluid distribution under the lens can improve the masking performance of the lens. The invention provides a soft contact lens for correcting a