CN-224203509-U - Coupling module and confocal microscope-optical tweezers integrated system

CN224203509UCN 224203509 UCN224203509 UCN 224203509UCN-224203509-U

Abstract

The utility model relates to a coupling module and a confocal microscope-optical tweezers integrated system, which relate to the technical field of optical instruments and comprise a shell, a first optical fiber, a second optical fiber, a first optical fiber and a second optical fiber, wherein the shell is provided with an installation space longitudinally penetrating through the shell; the side wall of the installation space is provided with a light passing hole, the dichroic mirror bracket is horizontally and linearly connected in the installation space in a sliding way, the pair Ji Tong of light holes, and the optical filter bracket is positioned in the installation space and is arranged on the dichroic mirror bracket. The dichroic mirror frame and the optical filter frame in the coupling module can slide, so that the optical path of the optical tweezers module and the optical path of the confocal microscope can be rapidly coupled and separated.

Inventors

KAN LINGYAN
GAO WEI
WANG XIXIAN
MA BO
XU JIAN

Assignees

中国科学院青岛生物能源与过程研究所

Dates

Publication Date: 20260505
Application Date: 20250605

Claims (10)

1. A coupling module, comprising: the shell is provided with an installation space which longitudinally penetrates through the shell, and the side wall of the installation space is provided with a light through hole; the dichroic mirror bracket is horizontally and linearly connected in the installation space in a sliding way, and is opposite to the Ji Tong light holes; and the filter frame is positioned in the installation space and is installed on the dichroic mirror frame.
2. The coupling module of claim 1, wherein the filter holder is horizontally slidably coupled to the dichroic mirror holder.
3. The coupling module of claim 2, wherein the sliding power source of the dichroic mirror mount is a linear drive, and the sliding power source of the filter mount is a linear drive.
4. The coupling module of claim 2, wherein the coupling module further comprises: a first pull rod penetrates through the shell and is connected with the shell in a sliding way, and one end of the first pull rod is connected with the dichroic mirror bracket; The first handle is positioned at the outer side of the shell and is connected with the other end of the first pull rod; The second pull rod penetrates through the shell and is connected with the shell in a sliding manner, and one end of the second pull rod is fixedly connected with the optical filter frame; The second handle is positioned at the outer side of the shell and is connected with the other end of the second pull rod.
5. The coupling module of claim 4, wherein the housing is provided with an upwardly open or downwardly open slot extending horizontally through a side wall of the housing, and wherein the coupling module further comprises a stop block removably coupled within the slot, the first and second tie rods extending through the stop block.
6. The coupling module of claim 5, wherein two limiting grooves are formed in the side surfaces of the limiting block, and the first pull rod and the second pull rod are respectively located in the two limiting grooves.
7. The coupling module of claim 5, wherein the coupling module further comprises: The first sliding rail is detachably connected in the installation space and is in sliding connection with the dichroic mirror frame; the second sliding rail is detachably connected with the dichroic mirror frame and is in sliding connection with the optical filter frame.
8. The coupling module of claim 7, further comprising a connection frame fixed to the housing, wherein the first slide rail and the stopper are both detachably connected to a same side of the connection frame.
9. A confocal microscope-optical tweezers integrated system is characterized by comprising the coupling module according to any one of claims 1-8, a confocal microscope and an optical tweezers module, wherein laser of the confocal microscope enters an installation space from the top of the installation space, and laser of the optical tweezers module enters the installation space from a light through hole.
10. The confocal microscope-optical tweezers integrated system of claim 9 wherein the confocal microscope is removably coupled to the housing of the coupling module and the optical tweezers module is removably coupled to the housing of the coupling module.

Description

Coupling module and confocal microscope-optical tweezers integrated system Technical Field The utility model relates to the technical field of optical instruments, in particular to a coupling module and a confocal microscope-optical tweezers integrated system. Background Single cell analysis can reveal the composition of a cell substance of a life basic unit, the diversity and the variability of physiological behaviors, and is a mainstream front-end technology of life analysis. The biggest challenge in single cell analysis is that the cell size is mostly in the micrometer scale or even in the submicron scale, and manipulation and analysis of single cells under the scale can certainly generate extremely high requirements on the aspects of precision, sensitivity and the like of the instrument. Chinese patent CN113136324a provides a coupling device, including top interface, light filter frame and dichroism mirror holder, bottom interface, first backup pad and second backup pad, top interface and bottom interface parallel arrangement are connected through first backup pad and second backup pad, be equipped with the light-passing hole in the first backup pad, the dichroism mirror holder is installed in the second backup pad, the light filter frame is installed in the first backup pad, top interface, light filter frame, dichroism mirror holder and bottom structure all are equipped with concentric circular holes. The coupling device can simply and quickly introduce the optical tweezers into a commercial microscope, and meanwhile, the optical tweezers are added into a sorting system, so that the microscopic-optical tweezers sorting system is formed, the limitation that the commercial microscope is only used for observation is broken, and multiple functions of observation and observation of single cells, capturing operation and separation and extraction are realized on one system. But only can the coupling and the separation of the optical tweezers optical path and the confocal microscope optical path be realized by disassembling and assembling the coupling device, which is time-consuming and labor-consuming. Disclosure of utility model Aiming at the problems that the coupling and the separation of the optical tweezers optical path and the confocal microscope optical path can be realized only by disassembling and assembling the coupling module at present, and time and labor are wasted, the utility model provides the coupling module and the confocal microscope-optical tweezers integrated system, and the coupling and the separation of the optical tweezers module optical path and the confocal microscope optical path can be realized rapidly by sliding the dichroic mirror frame and the optical filter frame. The utility model provides a coupling module, comprising: The shell is provided with an installation space longitudinally penetrating through the shell. The lateral wall in installation space sets up logical unthreaded hole. The dichroic mirror frame is horizontally and linearly connected in the installation space in a sliding way, and is opposite to Ji Tong light holes. And the filter frame is positioned in the installation space and is installed on the dichroic mirror frame. In some of these embodiments, the filter holder is horizontally linearly slidingly coupled to the dichroic mirror holder. In some of these embodiments, the sliding power source for the dichroic mirror mount is a linear drive. The sliding power source of the optical filter frame is a linear driving device. In some of these embodiments, the coupling module further comprises: And the first pull rod penetrates through the shell and is in sliding connection with the shell, and one end of the first pull rod is connected with the dichroic mirror bracket. The first handle is positioned at the outer side of the shell and is connected with the other end of the first pull rod. And the second pull rod penetrates through the shell and is in sliding connection with the shell, and one end of the second pull rod is fixedly connected with the optical filter frame. The second handle is positioned at the outer side of the shell and is connected with the other end of the second pull rod. In some of these embodiments, the housing is provided with slots with an upward opening or a downward opening, the slots extending horizontally through the side walls of the housing. The coupling module further comprises a limiting block which is detachably connected in the slot. The first pull rod and the second pull rod pass through the limiting block. In some embodiments, two limiting grooves are formed in the side face of the limiting block, and the first pull rod and the second pull rod are respectively located in the two limiting grooves. In some of these embodiments, the coupling module further comprises: The first sliding rail is detachably connected in the installation space and is in sliding connection with the dichroic mirror frame. The second sliding rail is detachably