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CN-224207770-U - Tangential flow filter fixing device

CN224207770UCN 224207770 UCN224207770 UCN 224207770UCN-224207770-U

Abstract

The utility model relates to a device for fixing a tangential flow filter, which at least comprises a base, an adjusting mechanism, a lifting sleeve and a clamping mechanism, wherein the adjusting mechanism is arranged on the base, the bottom end of the lifting sleeve is connected with one end, far away from the base, of the adjusting mechanism, the base is used for being connected with the tangential flow filter, the clamping mechanism is arranged on the lifting sleeve and can clamp the tangential flow filter to fix the tangential flow filter, a lifting rod is sleeved in the lifting sleeve, a pipeline mounting frame is arranged at the top end of the lifting rod and can fix a pipeline of the tangential flow filter, a locking mechanism is arranged at the top end of the lifting sleeve and can fix the height of the lifting rod. The utility model can firmly fix the tangential flow filter, thereby avoiding the situation that the tangential flow filter falls off and the tangential flow filter is interrupted.

Inventors

  • WANG TAO
  • GU FENG
  • LI XUE
  • SUN ZHENTAO

Assignees

  • 鲸智时代科技(北京)有限公司

Dates

Publication Date
20260508
Application Date
20250530

Claims (10)

  1. 1. Device for fixing a tangential flow filter, characterized in that it comprises at least a base (1), an adjusting mechanism, a lifting sleeve (6) and a clamping mechanism, wherein: The adjusting mechanism is arranged on the base (1), the bottom end of the lifting sleeve (6) is connected with one end, far away from the base (1), of the adjusting mechanism, and the base (1) is used for being connected with the tangential flow filtration system; The clamping mechanism is arranged on the lifting sleeve (6) and is capable of clamping the tangential flow filter so as to fix the tangential flow filter; a lifting rod (13) is sleeved in the lifting sleeve (6), a pipeline mounting frame (17) is mounted at the top end of the lifting rod (13), and the pipeline mounting frame (17) is arranged to be capable of fixing a pipeline of the tangential flow filtration system; The top end of the lifting sleeve (6) is provided with a locking mechanism which is arranged to fix the height of the lifting rod (13).
  2. 2. The device for fixing the tangential flow filter according to claim 1, wherein the adjusting mechanism comprises a rotating sleeve (2) fixedly installed at the top end of the base (1), a rotating column (4) is sleeved in the rotating sleeve (2), the top end of the rotating column (4) is located outside the rotating sleeve (2) and is connected with a connecting rod (5) through a bolt, the connecting rod (5) is perpendicular to the rotating column (4), one end of the connecting rod (5) away from the rotating column (4) is connected with the bottom end of a lifting sleeve (6) through a bolt, and the lifting sleeve (6) is parallel to the rotating sleeve (2).
  3. 3. The device for fixing the tangential flow filter according to claim 2, wherein a first knob threaded rod is mounted on the rotating sleeve (2) in a threaded manner, one end of the first knob threaded rod, which is close to the rotating column (4), is arranged to be capable of being abutted against the side wall of the rotating column (4), and one end of the first knob threaded rod, which is far away from the rotating column (4), is coaxially provided with a first knob (3).
  4. 4. The device for fixing the tangential flow filter according to claim 1, wherein the clamping mechanism comprises a first filter clamping piece (7), a second filter clamping piece (9) is hinged on the first filter clamping piece (7), and filter clamping grooves (19) are formed in the side walls of the first filter clamping piece (7) opposite to the second filter clamping piece (9); A third knob threaded rod is arranged on the second filter clamping piece (9) in a threaded manner, a third knob threaded hole is formed in the first filter clamping piece (7), the third knob threaded rod is arranged to be in threaded fit with the third knob threaded hole so as to clamp a tangential flow filter between two filter clamping grooves (19), and a third knob (11) is coaxially arranged at one end, far away from the third knob threaded hole, of the third knob threaded rod; The first filter clamping piece (7) is provided with a clamping connection part, and the clamping connection part is used for installing the first filter clamping piece (7) on the lifting sleeve (6).
  5. 5. The device for fixing a tangential flow filter according to claim 4, wherein the clamping connection comprises a lifting sleeve clamping piece (8) hinged to the first filter clamping piece (7), and clamping connection grooves are formed in the side walls of the first filter clamping piece (7) opposite to the lifting sleeve clamping piece (8), and the clamping connection grooves are matched with the lifting sleeve (6); The first filter clamping piece (7) is provided with a second knob threaded rod in a threaded mode, the lifting sleeve clamping piece (8) is provided with a second knob threaded hole, the second knob threaded rod is arranged to be in threaded fit with the second knob threaded hole, so that the lifting sleeve (6) is clamped between the two clamping connection grooves, the first filter clamping piece (7) is arranged on the lifting sleeve (6), and one end, far away from the second knob threaded hole, of the second knob threaded rod is provided with a second knob (10) in a coaxial mode.
  6. 6. Device for fixing a tangential flow filter according to claim 5, characterized in that the inner wall of the filter holding groove (19) and the inner wall of the holding connection groove are provided with an anti-slip layer.
  7. 7. The device for fixing a tangential flow filter according to claim 1, wherein the locking mechanism comprises a locking rotating sleeve (12), the inner side wall of the locking rotating sleeve (12) being screwed with the outer side wall of the top end of the lifting sleeve (6); A connecting block (16) is arranged in the locking rotating sleeve (12), a spring (15) is fixedly arranged on the connecting block (16), the tail end of the spring (15) is fixedly arranged at the top end of the lifting sleeve (6), and the top end of the connecting block (16) is abutted with the top end of the inner wall of the locking rotating sleeve (12) through the elastic force of the spring (15); The bottom end of the connecting block (16) is sequentially provided with a plurality of locking clamping pieces (14) along the circumferential direction of the connecting block, the locking clamping pieces (14) are positioned between the lifting sleeve (6) and the lifting rod (13), and two ends of the locking clamping pieces (14) are respectively abutted with the inner side wall of the lifting sleeve (6) and the outer side wall of the lifting rod (13); The bottom of one end of the locking clamping piece (14) far away from the lifting rod (13) is of an inclined structure, and the inclined direction of the inclined structure of the locking clamping piece (14) is arranged towards the lifting rod (13), so that the thickness of the upper end of the inclined structure of the locking clamping piece (14) is larger than that of the lower end of the inclined structure of the locking clamping piece (14); The inner side wall of the lifting sleeve (6) at the position corresponding to the inclined structure of the locking clamping piece (14) is of an inclined structure, and the inclined angle and the direction of the inclined structure of the lifting sleeve (6) are the same as those of the inclined structure of the locking clamping piece (14).
  8. 8. The device for fixing a tangential flow filter according to claim 7, wherein the outer side wall of the locking rotating sleeve (12) is provided with a plurality of anti-slip grooves along the axial direction thereof.
  9. 9. Device for fixing a tangential flow filter according to claim 1, characterized in that the pipe mounting (17) is of C-shaped construction and the connection of the pipe mounting (17) to the lifting rod (13) is located in the centre of the pipe mounting (17).
  10. 10. Device for fixing a tangential flow filter according to claim 9, characterized in that the end of the pipe mounting (17) remote from the lifting rod (13) is provided with a pipe mounting groove (18), in which pipe mounting groove (18) the pipe of the tangential flow filtration system is mounted.

Description

Tangential flow filter fixing device Technical Field The utility model relates to the technical field of tangential flow filtration, in particular to a device for fixing a tangential flow filter. Background Tangential Flow Filtration (TFF) systems are a high efficiency separation technique by which the surface of a filtration membrane is flushed by a parallel flow of liquid, the interior of which mainly comprises peristaltic pumps, tangential flow filters and tubing. Tangential Flow Filtration (TFF) systems are commonly used in biopharmaceutical applications such as monoclonal antibody purification, vaccine preparation and cell debris removal, as they allow for filtration and purification of feed solutions in pipelines, such as feed solutions containing cells, cell debris or derivatives thereof. However, in current tangential flow filtration systems, the tangential flow filter is typically secured using flange bolts or open clamps. But the flange bolts or open clamps do not firmly secure the tangential flow filter. Therefore, under the high-pressure working condition, the tangential flow filter is easy to shake, the tangential flow filter is easy to drop from the flange bolts or the open clamp, and the tangential flow filter is damaged, and meanwhile, the connection between a pipeline and the tangential flow filter is easy to break due to the shake generated by the tangential flow filter, so that the tangential flow filter is interrupted. Therefore, there is a need for a tangential flow filter fastening device that can firmly fasten a tangential flow filter and avoid dropping the tangential flow filter and interrupting the tangential flow filtration operation. Disclosure of utility model The object of the present utility model is to provide a tangential flow filter fastening device that solves the above mentioned problems of the prior art. In order to achieve the above object, the present utility model provides the following solutions: The utility model provides a device for fixing a tangential flow filter, which at least comprises a base, an adjusting mechanism, a lifting sleeve and a clamping mechanism, wherein: The adjusting mechanism is arranged on the base, the bottom end of the lifting sleeve is connected with one end, far away from the base, of the adjusting mechanism, and the base is used for being connected with the tangential flow filtration system; The clamping mechanism is arranged on the lifting sleeve and is used for clamping the tangential flow filter so as to fix the tangential flow filter; The lifting sleeve is sleeved with a lifting rod, a pipeline installation frame is installed at the top end of the lifting rod, and the pipeline installation frame is arranged to be capable of fixing a pipeline of the tangential flow filtration system; The locking mechanism is installed on the top end of the lifting sleeve, and the locking mechanism is arranged to be capable of fixing the height of the lifting rod. According to one embodiment of the utility model, the adjusting mechanism comprises a rotating sleeve fixedly arranged at the top end of the base, a rotating column is sleeved in the rotating sleeve in a sliding manner, the top end of the rotating column is positioned outside the rotating sleeve and is connected with a connecting rod through a bolt, the connecting rod is perpendicular to the rotating column, one end of the connecting rod, which is far away from the rotating column, is connected with the bottom end of the lifting sleeve through a bolt, and the lifting sleeve is parallel to the rotating sleeve. According to one embodiment of the utility model, a first knob threaded rod is arranged on the rotating sleeve in a threaded manner, one end of the first knob threaded rod, which is close to the rotating column, is arranged to be capable of being abutted against the side wall of the rotating column, and a first knob is coaxially arranged at one end of the first knob threaded rod, which is far away from the rotating column. According to one embodiment of the utility model, the clamping mechanism comprises a first filter clamping piece, a second filter clamping piece is hinged to the first filter clamping piece, and filter clamping grooves are formed in the side walls of the first filter clamping piece, which are opposite to the second filter clamping piece; A third knob threaded rod is arranged on the second filter clamping piece in a threaded manner, a third knob threaded hole is formed in the first filter clamping piece, and the third knob threaded rod is arranged to be in threaded fit with the third knob threaded hole so as to clamp the tangential flow filter between the two filter clamping grooves; The first filter clamping piece is provided with a clamping connection part, and the clamping connection part is used for installing the first filter clamping piece on the lifting sleeve. According to one embodiment of the utility model, the clamping connection part comprises a lifting sleeve