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CN-224207953-U - Laboratory constant pressure continuous reaction device

CN224207953UCN 224207953 UCN224207953 UCN 224207953UCN-224207953-U

Abstract

The utility model discloses a laboratory constant pressure continuous reaction device, which relates to the technical field of chemical reaction devices, and comprises an air source bottle, a reaction kettle and a sample injection bottle which are sequentially arranged; the reaction kettle is provided with a first air inlet, an air outlet, a liquid inlet and a feeding hole, the sample injection bottle is provided with a liquid outlet and a second air inlet, a first gas pipeline is arranged between the gas source bottle and the reaction kettle, one end of the first gas pipeline is connected with the air outlet end of the gas source bottle, the other end of the first gas pipeline is connected with the first air inlet, a second gas pipeline and a transfusion pipeline are arranged between the reaction kettle and the sample injection bottle, one end of the second gas pipeline is connected with the air outlet, the other end of the second gas pipeline is connected with the second air inlet, one end of the transfusion pipeline is connected with the liquid outlet, the other end of the transfusion pipeline is connected with the liquid inlet, and a peristaltic pump is arranged on the transfusion pipeline. The utility model can ensure that the reaction liquid is effectively added in the constant pressure process of the system through specific reaction equipment, and can simultaneously satisfy gas-liquid two-phase, micro-pressure and continuous reaction.

Inventors

  • LIANG FUWEN
  • LIU QINGRUI
  • DING XIANSHUAI
  • CHEN ZHI

Assignees

  • 陕西汉江药业集团股份有限公司

Dates

Publication Date
20260508
Application Date
20250519

Claims (7)

  1. 1. The constant-pressure continuous reaction device for the laboratory is characterized by comprising an air source bottle (5), a reaction kettle (1) and a sample injection bottle (2) which are sequentially arranged; the reaction kettle (1) is provided with a first air inlet (1A), an air outlet (1B), a liquid inlet (1C) and a feed inlet (1D); a liquid outlet (2A) and a second air inlet (2B) are formed in the sample injection bottle (2); A first gas pipeline (8) is arranged between the gas source bottle (5) and the reaction kettle (1), one end of the first gas pipeline (8) is connected with the gas outlet end of the gas source bottle (5), and the other end of the first gas pipeline is connected with the first gas inlet (1A); A second gas pipeline (9) and a transfusion pipeline (7) are arranged between the reaction kettle (1) and the sample injection bottle (2), one end of the second gas pipeline (9) is connected with the gas outlet (1B), the other end of the second gas pipeline is connected with the second gas inlet (2B), one end of the transfusion pipeline (7) is connected with the liquid outlet (2A), the other end of the transfusion pipeline is connected with the liquid inlet (1C), and a peristaltic pump (4) is arranged on the transfusion pipeline (7).
  2. 2. The laboratory constant pressure continuous reaction device according to claim 1, wherein, The device also comprises a temperature control system (3), wherein the temperature control system (3) is provided with a circulating liquid flow inlet (3A) and a circulating liquid flow outlet (3B); the periphery of the reaction kettle (1) is provided with a first jacket (10), one side of the upper part of the first jacket (10) is provided with a first circulating liquid inlet (10A), and one side of the lower part of the first jacket is provided with a first circulating liquid outlet (10B); The periphery of the sample injection bottle (2) is provided with a second jacket (11), one side of the upper part of the second jacket (11) is provided with a second circulating liquid inlet (11A), and one side of the lower part of the second jacket is provided with a second circulating liquid outlet (11B); The circulating liquid flow outlet (3B) is connected with the first circulating liquid inlet (10A) and the second circulating liquid inlet (11A) through a first circulating liquid pipeline (12), and the circulating liquid flow inlet (3A) is connected with the first circulating liquid outlet (10B) and the second circulating liquid outlet (11B) through a second circulating liquid pipeline (13).
  3. 3. The laboratory constant pressure continuous reaction device according to claim 2, wherein a magnetic stirrer (6) is arranged at the bottom of the reaction kettle (1), and the magnetic stirrer (6), the peristaltic pump (4) and the sample injection bottle (2) are all fixed on an iron stand (14).
  4. 4. The laboratory constant pressure continuous reaction device according to claim 2, characterized in that the first gas pipe (8), the second gas pipe (9), the infusion pipe (7), the first circulation liquid pipe (12) and the second circulation liquid pipe (13) are latex pipes.
  5. 5. The laboratory constant pressure continuous reaction device according to claim 1, characterized in that the reaction kettle (1) is further provided with a pressure gauge (15) and a thermometer (16).
  6. 6. The laboratory constant pressure continuous reaction device according to claim 1, characterized in that the first air inlet (1A) and the air outlet (1B) are in communication with the inside of the reaction kettle (1) through a three-way valve (17).
  7. 7. The laboratory constant pressure continuous reaction device according to claim 1, wherein the reaction vessel (1) is a glass pressurized reaction vessel.

Description

Laboratory constant pressure continuous reaction device Technical Field The utility model relates to the technical field of chemical reaction devices, in particular to a laboratory constant-pressure continuous reaction device. Background In the organic synthesis reaction, some gas-liquid two-phase reactions are often involved, the reaction can be realized by air blowing or pressurization, the air blowing can cause waste of gas raw materials and accelerate solvent volatilization, and the pressurization is preferred to realize the gas-liquid reaction. The common pressurizing device is a metal autoclave, which is heavy and bulky and is unfavorable for the operation in the laboratory stage. In the actual organic synthesis, the reaction rate is controlled by adding raw materials once or dripping, and when the gas-liquid two phases are involved, the pressurization and the raw material dripping cannot be satisfied for some unstable reaction raw materials in the solvent. Therefore, in order to solve the above problems, a detachable miniaturized pressurized continuous reaction apparatus in a laboratory is required. Disclosure of utility model Accordingly, the present utility model is directed to a laboratory constant pressure continuous reaction apparatus, which solves the problems of the prior art. In order to achieve the above purpose, the technical scheme of the utility model is as follows: a laboratory constant pressure continuous reaction device comprises an air source bottle, a reaction kettle and a sample injection bottle which are sequentially arranged; The reaction kettle is provided with a first air inlet, an air outlet, a liquid inlet and a feed inlet; a liquid outlet and a second air inlet are arranged on the sample injection bottle; A first gas pipeline is arranged between the gas source bottle and the reaction kettle, one end of the first gas pipeline is connected with the gas outlet end of the gas source bottle, and the other end of the first gas pipeline is connected with the first gas inlet; A second gas pipeline and a transfusion pipeline are arranged between the reaction kettle and the sample injection bottle, one end of the second gas pipeline is connected with the gas outlet, the other end of the second gas pipeline is connected with the second gas inlet, one end of the transfusion pipeline is connected with the liquid outlet, the other end of the transfusion pipeline is connected with the liquid inlet, and a peristaltic pump is arranged on the transfusion pipeline. Further, the system also comprises a temperature control system, wherein the temperature control system is provided with a circulating liquid flow inlet and a circulating liquid flow outlet; The periphery of the reaction kettle is provided with a first jacket, one side of the upper part of the first jacket is provided with a first circulating liquid inlet, and one side of the lower part of the first jacket is provided with a first circulating liquid outlet; The periphery of the sample injection bottle is provided with a second jacket, one side of the upper part of the second jacket is provided with a second circulating liquid inlet, and one side of the lower part of the second jacket is provided with a second circulating liquid outlet; The circulating liquid flow outlet is connected with the first circulating liquid inlet and the second circulating liquid inlet through a first circulating liquid pipeline, and the circulating liquid flow inlet is connected with the first circulating liquid outlet and the second circulating liquid outlet through a second circulating liquid pipeline. Further, a magnetic stirrer is arranged at the bottom of the reaction kettle, and the magnetic stirrer, the peristaltic pump and the sample injection bottle are all fixed on an iron stand. Further, the first gas pipeline, the second gas pipeline, the infusion pipeline, the first circulating liquid pipeline and the second circulating liquid pipeline are all latex pipelines. Further, the reaction kettle is also provided with a pressure gauge and a thermometer. Further, the first air inlet and the air outlet are communicated with the inside of the reaction kettle through a three-way valve. Further, the reaction kettle is a glass pressurized reaction kettle. The utility model has the beneficial effects that: The reaction device solves the problem of continuous flow reaction in a laboratory in the reaction process with pressure, can ensure that the reaction liquid is effectively added in the constant pressure process of the system, can simultaneously realize gas-liquid two-phase, micro-pressure and continuous reaction, can adjust the sample injection rate of the peristaltic pump according to the reaction rate and the reaction temperature, and can stop the reaction according to actual conditions after the liquid in the sample injection bottle completely enters the reaction kettle, and then the peristaltic pump is closed for pressure maintaining and continuous rea