CN-224220127-U - Vertebra clamp holder for two-photon recording

CN224220127UCN 224220127 UCN224220127 UCN 224220127UCN-224220127-U

Abstract

The application provides a vertebra holder for two-photon recording, which comprises a first support, a second support, a lead screw and a clamping space, wherein the first support comprises a first clamping arm arranged along a first direction, a first extending plate arranged along the first direction and connected with the first clamping arm, and a first connecting plate arranged along a second direction, the first connecting plate is connected with the first extending plate, the second support comprises a second clamping arm arranged along the first direction, a second extending plate arranged along the first direction and connected with the second clamping arm, and a second connecting plate arranged along the second direction, the second connecting plate is connected with the first connecting plate in a sliding mode along the second direction, the lead screw is arranged along the second direction and connected with the first extending plate and the second extending plate, and the lead screw and the clamping space are respectively positioned on two opposite sides of the first connecting plate and the second connecting plate in the first direction. The spine clamp disclosed by the application has the advantages of high structural strength and high structural stability, and can be adapted to the spine structure of smaller animals and the spine structure of larger animals.

Inventors

CUI GUANGFU
HUANG TIANWEN
CHE XIAOJING
CHEN FENGMING
KE JIN
WEN SHANYU

Assignees

中国科学院深圳先进技术研究院

Dates

Publication Date: 20260512
Application Date: 20250418

Claims (10)

1. A spinal holder for two-photon recording, the spinal holder comprising: The first bracket comprises a first clamping arm arranged along a first direction, a first extension plate arranged along the first direction and connected with the first clamping arm, and a first connecting plate arranged along a second direction, wherein the first connecting plate is connected with the first extension plate, and the first direction is different from the second direction; The second bracket comprises a second clamping arm arranged along the first direction, a second extension plate arranged along the first direction and connected with the second clamping arm, and a second connecting plate arranged along the second direction, wherein the second connecting plate is connected with the second extension plate and can be connected with the first connecting plate in a sliding manner along the second direction, and a clamping space with adjustable clamping length in the second direction is formed between the first clamping arm and the second clamping arm; The lead screw is arranged along the second direction and connected with the first extension plate and the second extension plate, and the lead screw and the clamping space are respectively positioned on two opposite sides of the first connection plate and the second connection plate in the first direction.
2. The spinal holder of claim 1 wherein, The first connecting plate is provided with an opening extending along the second direction, the second extending plate can slidably penetrate through the opening along the second direction, and the second connecting plate abuts against one side of the opening and is detachably connected with the first connecting plate.
3. The spinal holder of claim 2, further comprising: The cover plate and the second connecting plate are respectively propped against two opposite sides of the opening in the second direction, and the second connecting plate is connected with the cover plate through a first connecting piece penetrating through the opening so as to jointly clamp the first connecting plate with the cover plate.
4. The spinal holder of claim 1 wherein, The first support includes two in the third direction side by side and interval setting first centre gripping arm, the second support includes two in the third direction side by side and interval setting second centre gripping arm, the third direction is perpendicular to first direction with the second direction.
5. The spinal holder as recited in any one of claims 1-4, wherein, The first direction is perpendicular to the second direction.
6. The spinal holder as recited in any one of claims 1-4, wherein, The first and second clamping arms are provided with anti-slip teeth on the sides facing each other.
7. The spinal holder of any one of claims 1 to 4, further comprising: The base is provided with a mounting side surface, a mounting groove extending along the second direction is formed in the mounting side surface, and a part of the first connecting plate is embedded into the mounting groove and detachably connected with the base.
8. The spinal holder of claim 7 wherein the base comprises: The first base plate is arranged along the second direction, and the side surface of the first base plate facing the lead screw is the mounting side surface; the second base plate is arranged along the first direction and is perpendicular to the first base plate.
9. The spinal holder of any one of claims 1 to 4, further comprising: The locating piece comprises a locating ring sleeved on the first clamping arm and the second clamping arm and a locating ring connected with the locating ring, and locating holes defined by the locating ring correspond to and are communicated with the clamping space.
10. The spinal holder of claim 9 wherein, The first bracket comprises two first clamping arms which are arranged side by side and at intervals in a third direction, the second bracket comprises two second clamping arms which are arranged side by side and at intervals in the third direction, and the third direction is perpendicular to the first direction and the second direction; The locating pieces are two, one locating ring of the locating piece is sleeved outside the first clamping arm and the second clamping arm, the other locating ring of the locating piece is sleeved outside the first clamping arm and the second clamping arm, and the locating rings of the two locating pieces are respectively located on two opposite sides of the clamping space in the third direction.

Description

Vertebra clamp holder for two-photon recording Technical Field The utility model provides the technical field of animal experiment equipment, in particular to a vertebra holder for two-photon recording. Background The dorsal root ganglion is an important peripheral nerve tissue for human and vertebrate perception of peripheral stimulation, and is also an important post for the transmission of peripheral sensory codes to the spinal cord. In studying the neural coding mechanisms of sensory sensations such as pain, itching, touch, cold and heat, there is a need to study the differences in the responses of dorsal root ganglion neurons under different peripheral condition stimuli. At present, a two-photon microscope is adopted to record the activity of dorsal root neurons so as to analyze the coding mechanism of peripheral sensory perception, and the method belongs to the front field of neuroscience. However, the development of spinal cord fixing devices for two-photon recording is still imperfect, and poor stability and durability of the existing devices may result in poor fixation firmness of the spinal cord, thereby causing shaking of the field of view and further affecting the imaging quality. It should be noted that the foregoing description of the background art is only for the purpose of providing a clear and complete description of the technical solution of the present application and is presented for the purpose of facilitating understanding by those skilled in the art. The above-described solutions are not considered to be known to the person skilled in the art simply because they are set forth in the background of the application section. Disclosure of utility model It is an object of the present application to provide a spinal holder for two-photon recording that solves the above-mentioned problems identified in the background art or other similar problems. The embodiment of the application provides a vertebra holder for two-photon recording, which comprises a first bracket, a second bracket, a screw and a second connecting plate, wherein the first bracket comprises a first clamping arm arranged along a first direction, a first extending plate arranged along the first direction and connected with the first clamping arm, and a first connecting plate arranged along a second direction, the first connecting plate is connected with the first extending plate, the first direction is different from the second direction, the second bracket comprises a second clamping arm arranged along the first direction, a second extending plate arranged along the first direction and connected with the second clamping arm, and a second connecting plate arranged along the second direction, the second connecting plate is connected with the second extending plate, the second connecting plate can be connected with the first connecting plate in a sliding manner along the second direction, a clamping space with an adjustable clamping length in the second direction is formed between the first clamping arm and the second clamping arm, the screw is arranged along the second direction, the second connecting plate and the second connecting plate are connected with the first connecting plate and the second connecting plate in the opposite directions, and the second connecting plate and the first connecting plate and the second connecting plate are respectively located on two sides of the first connecting plate and the second connecting plate. In some embodiments, the first connecting plate is provided with an opening extending along the second direction, the second extending plate can slidably pass through the opening along the second direction, and the second connecting plate abuts against one side of the opening and is detachably connected with the first connecting plate. In some embodiments, the spinal holder further includes a cover plate respectively abutting opposite sides of the opening in the second direction with the second connection plate connected to the cover plate by a first connection passing through the opening to hold the first connection plate together with the cover plate. In some embodiments, the first bracket includes two first clamping arms arranged side by side and spaced apart in a third direction, and the second bracket includes two second clamping arms arranged side by side and spaced apart in the third direction, the third direction being perpendicular to the first direction and the second direction. In some embodiments, the first direction is perpendicular to the second direction. In some embodiments, the first and second clamping arms are provided with anti-slip teeth on sides facing each other. In some embodiments, the spinal holder further includes a base having a mounting side with a mounting recess extending in the second direction, a portion of the first connection plate being embedded in the mounting recess and removably coupled to the base. In some embodiments, the base comprises a first base plate a