CN-224221385-U - Cross-contamination-preventing metal bath

Abstract

The utility model provides a metal bath capable of preventing cross contamination, which comprises a metal bath body and a heating template arranged in the metal bath body and provided with an upward centrifuge tube hole site, wherein a hemispherical cover plate is hinged above the metal bath body, and a centrifuge tube plug pressing assembly penetrating and extending to the upper part of the hemispherical cover plate is arranged on the hemispherical cover plate. According to the cross-contamination-preventing metal bath, the sample pressing plate is additionally arranged on the metal bath, and the sample pressing plate can firmly press the cover plug of the centrifuge tube through the adjustment of the screw rod on the nut, so that the cover plug is effectively prevented from being sprung open due to the increase of the steam pressure in the tube. Therefore, small molecular DNA/RNA fragments in the positive sample can not splash to form aerosol due to the flicking of the cover plug, and other negative samples can not be polluted, so that false positives of negative sample detection results are avoided, the accuracy and reliability of DNA/RNA detection are greatly improved, the experimental results are ensured to truly reflect the sample conditions, and accurate basis is provided for medical diagnosis.

Inventors

• ZHANG ZHENLIN
• WANG MULAN
• LI MING
• ZHOU ENWU
• XU JING
• ZHANG SHIQI
• LI RUIWEN
• TANG LI
• GUO HONGLI

Assignees

• 中国人民解放军联勤保障部队第九九一医院

Dates

Publication Date

20260512

Application Date

20250402

Claims (6)

1. 1. The metal bath capable of preventing cross contamination comprises a metal bath body (10) and a heating template (20) which is arranged in the metal bath body and provided with a hole site for an upward centrifuge tube, wherein a hemispherical cover plate (30) is hinged above the metal bath body (10), and the metal bath is characterized in that a centrifugal tube plug pressing assembly (40) which extends to the upper side of the hemispherical cover plate is arranged on the hemispherical cover plate (30), the centrifugal tube plug pressing assembly (40) comprises a sample pressing plate (43) with the bottom for abutting against the centrifugal tube plug and a screw rod (41) arranged above the sample pressing plate (43), the screw rod (41) is in threaded connection with a nut (42) arranged in the hemispherical cover plate (30) and extends to the upper side of the hemispherical cover plate (30), and the screw rod (41) is forced to enable the screw rod (41) to feed in a straight line mode and drive the sample pressing plate (43) to ascend or descend.
2. 2. The cross-contamination prevention metal bath according to claim 1, characterized in that the sample platen (43) is a circular plate with an arcuate slope at its outer edge adapted to the inner wall of the hemispherical cover plate (30).
3. 3. The cross-contamination prevention metal bath according to claim 1, further comprising a heat radiation fan (44) between the screw (41) and the sample pressing plate (43), wherein a bracket (45) formed by a plurality of L-shaped ribs in a circular equidistant combination is arranged below the screw (41), the bottom of the bracket (45) is fixed on the top of the sample pressing plate (43), and the heat radiation fan (44) is arranged below the bracket (45).
4. 4. A cross-contamination prevention metal bath according to claim 3, wherein the top wall of the hemispherical cover plate (30) is provided with an air inlet (31), the side wall of the hemispherical cover plate (30) is provided with an air outlet (32), the sample pressing plate (43) is provided with a vent hole, and the action of the cooling fan (44) enables air to enter the hemispherical cover plate (30) from the top of the hemispherical cover plate (30) and pass through the vent hole to cool a centrifuge tube and discharge from the air outlet (32).
5. 5. The metal bath for preventing cross contamination according to claim 4, wherein the air inlet (31) and the air outlet (32) are provided therein with a check plate a (33) and a check plate b (34), the movement direction of the check plate a (33) is directed toward the inside of the hemispherical cover plate (30), and the movement direction of the check plate b (34) is directed toward the outside of the hemispherical cover plate (30).
6. 6. The cross-contamination prevention metal bath according to claim 1, characterized in that a handle (46) is provided above the screw (41).

Description

Cross-contamination-preventing metal bath Technical Field The utility model relates to the technical field of medical equipment, in particular to a cross-contamination prevention metal bath. Background DNA/RNA is a small molecule with very light mass, and in the process of detecting certain DNA/RNA in a sample, the DNA/RNA needs to be manually extracted, a centrifuge tube with a snap-on cover is needed in the extraction process, and high-temperature incubation equipment is used in the manual operation. The metal bath equipment used in the laboratory at present is provided with a heating device only, and no device for protecting the sample is provided. The temperature is usually set at 100 ℃, when the centrifuge tube containing the extracting solution and the sample is in incubation, the plug of the centrifuge tube is flicked off due to the increase of the steam pressure in the tube, and in the flicking off process, small molecular DNA/RNA fragments of a positive sample with very light mass can splash to form aerosol to pollute other negative samples exposed due to the steam pressure, so that the test result of the negative samples is false positive, and the risk of aerosol pollution in a laboratory is increased. Disclosure of Invention Aiming at the defects existing in the existing equipment, the technical scheme of the utility model increases the sample pressing plate, presses the cover plug by using external force in the incubation process of the centrifuge tube, prevents the cover plug of the centrifuge tube from bouncing off due to steam pressure, avoids cross contamination generated in the extraction process of DNA/RNA, and reduces the risk of aerosol pollution in a laboratory. The technical scheme of the utility model is realized as follows: A metal bath capable of preventing cross contamination comprises a metal bath body and a heating template arranged in the metal bath body and provided with an upward centrifuge tube hole site, wherein a hemispherical cover plate is hinged above the metal bath body, a centrifugal tube plug pressing assembly penetrating and extending to the upper side of the hemispherical cover plate is arranged on the hemispherical cover plate, the centrifugal tube plug pressing assembly comprises a sample pressing plate with the bottom being used for abutting against the centrifugal tube plug and a screw rod arranged above the sample pressing plate, the screw rod is in threaded connection with a nut arranged in the hemispherical cover plate and extends to the upper side of the hemispherical cover plate, and the screw rod is applied with force to enable the screw rod to linearly screw and drive the sample pressing plate to ascend or descend. Further, the sample pressing plate is a circular plate, and an arc slope matched with the inner wall of the hemispherical cover plate is arranged at the outer edge of the sample pressing plate. The sample pressing plate is characterized by further comprising a cooling fan positioned between the screw rod and the sample pressing plate, wherein a bracket formed by a plurality of L-shaped ribs in an annular equidistant combination mode is arranged below the screw rod, the bottom of the bracket is fixed at the top of the sample pressing plate, and the cooling fan is arranged below the bracket. Further, the air inlet is formed in the top wall of the hemispherical cover plate, the air outlet is formed in the side wall of the hemispherical cover plate, the vent holes are formed in the sample pressing plate, and the action of the cooling fan enables air to enter the hemispherical cover plate from the top of the hemispherical cover plate and pass through the vent holes to cool the centrifuge tube and be discharged from the air outlet. Further, the air inlet and the air outlet are internally provided with a non-return plate a and a non-return plate b, the movement direction of the non-return plate a faces the inside of the hemispherical cover plate, and the movement direction of the non-return plate b faces the outside of the hemispherical cover plate. Further, a handle is arranged above the screw rod. The technical scheme provided by the application has the beneficial effects that: According to the cross-contamination-preventing metal bath, the sample pressing plate is additionally arranged on the metal bath, and the sample pressing plate can firmly press the cover plug of the centrifuge tube through the adjustment of the screw rod on the nut, so that the cover plug is effectively prevented from being sprung open due to the increase of the steam pressure in the tube. Therefore, small molecular DNA/RNA fragments in the positive sample can not splash to form aerosol due to the flicking of the cover plug, and other negative samples can not be polluted, so that false positives of negative sample detection results are avoided, the accuracy and reliability of DNA/RNA detection are greatly improved, the experimental results are ensured to truly reflect the sam