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CN-224221480-U - Novel tumor tissue fine grinding device

CN224221480UCN 224221480 UCN224221480 UCN 224221480UCN-224221480-U

Abstract

The utility model discloses a novel tumor tissue fine grinding device, in particular to the field of tumor grinding, which comprises a treatment cylinder, wherein an inlet pipe is fixedly communicated with the left side of the top of the treatment cylinder, a grinding mechanism is arranged in the treatment cylinder, the grinding mechanism comprises a motor fixedly connected to the top of the treatment cylinder, and the output end of the motor is fixedly connected with a rotating rod which can be rotatably connected to the top of the inner side of the treatment cylinder. The rotary rod is driven to rotate through the output end of the motor, so that the rotary blade, the umbrella-shaped blade and the arc-shaped block are driven to rotate, if tumor tissues are larger, the rotary blade can cut the tumor tissues into blocks, the block-shaped tumor tissues slide outwards along the surface of the arc-shaped umbrella body and are further cut by the rotating tool tips until the tumor blocks are smaller than the distance between two adjacent tool tips, the lower filter screen can be fallen into, and the grinding beads rolling along the surface of the filter screen below the rotary arc-shaped block are impacted and rubbed into fine particles, so that the effect of rapid fine grinding of the tumor tissues is achieved.

Inventors

  • ZHU JING
  • PU YANG
  • YANG MIAO

Assignees

  • 四川祜宇生物科技有限公司

Dates

Publication Date
20260512
Application Date
20250530

Claims (7)

  1. 1. The utility model provides a novel tumour tissue fine grinding device, includes treatment cylinder (10), the fixed intercommunication in top left side of treatment cylinder (10) has admission tube (12), its characterized in that, the inside of treatment cylinder (10) is provided with grinding mechanism (20), grinding mechanism (20) are including motor (201) of fixed connection at treatment cylinder (10) top, the output fixedly connected with of motor (201) can handle dwang (202) that the inboard top of section of thick bamboo (10) rotates to be connected, the outside from the top down fixedly connected with rotary blade (203), umbrella blade (204), arc piece (205) in proper order, the bottom fixed mounting of arc piece (205) has multiunit grinding pearl (206).
  2. 2. The novel fine grinding device for tumor tissues according to claim 1, wherein the umbrella-shaped blade (204) comprises an arc-shaped umbrella body (2041) fixedly connected with a rotating rod (202), and a group of circumferentially arranged knife points (2042) are fixedly connected to the outer side of the arc-shaped umbrella body (2041).
  3. 3. The novel tumor tissue fine grinding device according to claim 1, wherein the bottom of the treatment cylinder (10) is connected with a receiving cylinder (11) through an installing and detaching mechanism (30), an annular gap is formed in the bottom of the treatment cylinder (10), a filter screen (207) is arranged at the gap, and the filter screen (207) is in surface contact with grinding beads (206).
  4. 4. The novel tumor tissue fine grinding device according to claim 3, wherein the mounting and dismounting mechanism (30) comprises a connecting ring (301) fixedly connected to the top of the receiving cylinder (11), a group of positioning grooves (302) are formed in the outer side of the connecting ring (301), a group of circumferentially arranged fixing grooves (305) are formed in the outer side of a notch at the bottom of the treatment cylinder (10), and positioning blocks (307) matched with the cross sections of the fixing grooves (305) are slidably connected in the fixing grooves (305).
  5. 5. The novel tumor tissue fine grinding device according to claim 4, wherein a pair of connecting columns (303) which are arranged left and right are fixedly connected to the top of the connecting ring (301), through holes are respectively formed in the left side and the right side of the top of the filter screen (207), and a butt joint groove (304) which is matched with the connecting columns (303) is formed in the top of a bottom gap of the treatment cylinder (10).
  6. 6. The novel tumor tissue fine grinding device according to claim 4, wherein a supporting spring (306) is fixedly connected to the outer side of the positioning block (307), the outer side of the supporting spring (306) is fixedly connected with a fixed groove (305), a pair of ring-shaped guide rails (308) which are mirror symmetrical up and down are fixedly connected to the outer side of the treatment cylinder (10), a swivel (309) is slidingly connected to the inner parts of the two ring-shaped guide rails (308) together, a connecting rope (310) is fixedly connected to the outer side of the group of positioning blocks (307), and the outer side of the connecting rope (310) penetrates through the fixed groove (305) and is fixedly connected with the swivel (309).
  7. 7. The novel fine grinding device for tumor tissue according to claim 6, wherein the inner side surface of the positioning block (307) is of an arc design which is gradually lengthened from bottom to top.

Description

Novel tumor tissue fine grinding device Technical Field The utility model relates to the technical field of tumor grinding, in particular to a novel tumor tissue fine grinding device. Background Tumor tissue milling is a kerbstone procedure for tumor medical research and clinical detection. The method can crush the cell structure of tumor tissue by grinding, release biomolecules such as nucleic acid and protein in cells, provide basic samples for gene sequencing, proteome analysis and the like, and simultaneously prepare high-quality single-cell suspension and analyze tumor heterogeneity by using the front-edge technologies such as assisted flow cytometry, single-cell sequencing and the like. The accuracy and the efficiency of the method directly influence the reliability of subsequent experiments, and the method has key significance for research on tumor pathogenesis, development of targeted drugs and clinical pathological diagnosis. The Chinese patent discloses a novel tumor tissue fine grinding device with the publication number of CN216172903U, the application date is 2021.11.03, the technology of the patent is characterized in that the size of the inner wall of a second grinding cavity is that the diameter of the bottom circle is cm, the height is cm, a tumor tissue sample with the size of 1cm x 1cm can be put into the second grinding cavity, then a rotating shaft is inserted into the second grinding cavity, the lower end face of a shell is contacted with the upper end face of a first grinding cavity, a starting button is pressed to enable a motor to drive the rotating shaft so as to drive a blade below to grind the tumor tissue sample in the second grinding cavity, and the size of the second grinding cavity is smaller, so that the movable range of the tumor tissue sample is smaller during grinding, and the effect of fully grinding the small-size tumor tissue sample can be achieved. Accordingly, the present inventors have provided a novel tumor tissue fine grinding device to solve the problems set forth in the background art described above. Disclosure of utility model The utility model aims to provide a novel tumor tissue fine grinding device, so that the effect of rapidly and finely grinding tumor tissue is achieved. The aim of the utility model can be achieved by the following technical scheme: The utility model provides a novel tumour tissue fine grinding device, is including handling a section of thick bamboo, the fixed intercommunication in top left side that handles the section of thick bamboo is provided with grinding mechanism, and grinding mechanism includes the motor of fixed connection at handling a section of thick bamboo top, but the output fixedly connected with handle a section of thick bamboo inboard top rotation connection's dwang, the outside from the top down of dwang fixedly connected with rotary blade, umbrella blade, arc piece in proper order, the bottom fixed mounting of arc piece has multiunit grinding beads. As a still further proposal of the utility model, the umbrella-shaped blade comprises an arc-shaped umbrella body fixedly connected with a rotating rod, and a group of knife tips which are circumferentially distributed are fixedly connected on the outer side of the arc-shaped umbrella body. As a still further proposal of the utility model, the bottom of the treatment cylinder is connected with a receiving cylinder through an installing and detaching mechanism, the bottom of the treatment cylinder is provided with a ring-shaped vacancy, and the vacancy is provided with a filter screen which is contacted with the surface of the grinding beads. The utility model further provides a further scheme that the mounting and dismounting mechanism comprises a connecting ring fixedly connected to the top of the receiving cylinder, a group of positioning grooves are formed in the outer side of the connecting ring, a group of circumferentially arranged fixing grooves are formed in the outer side of a notch at the bottom of the processing cylinder, and positioning blocks matched with the cross sections of the fixing grooves are connected in a sliding mode in the fixing grooves. As a still further proposal of the utility model, the top of the connecting ring is fixedly connected with a pair of connecting columns which are arranged left and right, the left and right sides of the top of the filter screen are respectively provided with a through hole, and the top of a bottom notch of the treatment cylinder is provided with a butt joint groove which is matched with the connecting columns. The utility model further provides a scheme that the outer side of the positioning block is fixedly connected with a supporting spring, the outer side of the supporting spring is fixedly connected with a fixed groove, the outer side of the treatment cylinder is fixedly connected with a pair of ring-shaped guide rails which are mirror-symmetrical up and down, the interiors of the two ring-shaped guide rails ar