Search

CN-224227017-U - Space multiunit science transfer device

CN224227017UCN 224227017 UCN224227017 UCN 224227017UCN-224227017-U

Abstract

The utility model belongs to the technical field of space multiunit science, and discloses a space multiunit science transfer device which comprises a base, a hinge, a first limiting component and a second limiting component, wherein the base is used for bearing a chip, the hinge is used for bearing a glass slide, the hinge is provided with a rotating part, the rotating part is rotationally connected with the base so as to enable the chip and the glass slide to be selectively buckled and arranged, the first limiting component is arranged on the base and used for limiting the relative position of the chip and the base, and the second limiting component is arranged on the hinge and used for limiting the relative position of the glass slide and the hinge. So, chip and slide glass can be respectively by base and hinge bearing, can make chip and slide glass lock through rotating the hinge, improve tissue transfer efficiency, simplify the operation process, and space multiunit school transfer device compact structure retrencies, can reduce equipment cost.

Inventors

  • ZHENG HONGKUN
  • LIU MIN
  • ZHANG MENGLONG
  • GUO HUANPENG

Assignees

  • 青岛百创智能制造技术有限公司

Dates

Publication Date
20260512
Application Date
20250527

Claims (10)

  1. 1. A spatial multi-chemical transfer device, comprising: The device comprises a base (3) and a hinge (4), wherein the base (3) is used for bearing a chip (1), the hinge (4) is used for bearing a glass slide (2), the hinge (4) is provided with a rotating part (41), and the rotating part (41) is rotationally connected with the base (3) so as to enable the chip (1) and the glass slide (2) to be selectively buckled; The first limiting assembly (5) is arranged on the base (3) and used for limiting the relative positions of the chip (1) and the base (3); the second limiting assembly (6), the second limiting assembly (6) set up in hinge (4) is used for limiting slide glass (2) with the relative position of hinge (4).
  2. 2. The device for transferring the multiple sets of the space science according to claim 1, wherein the base (3) is provided with a first limit groove (31) for limiting the position of the chip (1), and the hinge (4) is provided with a second limit groove (42) for limiting the position of the glass slide (2).
  3. 3. The spatial multiplexing transfer apparatus of claim 2 wherein a length direction of the first limiting groove (31) is perpendicular to a length direction of the second limiting groove (42).
  4. 4. The device according to claim 1, wherein one of the base (3) and the hinge (4) is provided with a connecting portion (43), the other is provided with a connecting block (32) corresponding to the connecting portion (43), and the connecting portion (43) and the connecting block (32) are selectively buckled.
  5. 5. The device according to claim 4, characterized in that the connecting portion (43) is arranged at an end of the hinge (4) facing away from the rotating portion (41).
  6. 6. The spatial multiunit chemical transferring device according to claim 1, wherein the first limiting component (5) comprises a first limiting block (51) and a first clamping block (52), the first limiting block (51) is fixedly arranged on the base (3), the first clamping block (52) is slidably arranged on the base (3), the first limiting block (51) and the first clamping block (52) are respectively arranged on two sides of the chip (1), the second limiting component (6) comprises a second limiting block (61) and a second clamping block (62), the second limiting block (61) is fixedly arranged on the hinge (4), the second clamping block (62) is slidably arranged on the hinge (4), and the second limiting block (61) and the second clamping block (62) are respectively arranged on two sides of the glass slide (2).
  7. 7. The device according to claim 6, characterized in that the first clamping block (52) is connected with a first spring to enable the first clamping block (52) and the first limiting block (51) to clamp the chip (1), and/or the second clamping block (62) is connected with a second spring to enable the second clamping block (62) and the second limiting block (61) to clamp the slide (2).
  8. 8. The device according to claim 6, wherein the base (3) is provided with a receiving groove (33) corresponding to the second limiting block (61) and the second clamping block (62), and the second limiting block (61) and the second clamping block (62) are located in the receiving groove (33) when the chip (1) is attached to the slide glass (2).
  9. 9. The spatial multi-group chemical transferring device according to any one of claims 1 to 8, wherein the first limiting assembly (5) is provided with at least two groups at intervals along the length direction of the base (3), and/or the second limiting assembly (6) is provided with at least two groups at intervals along the length direction of the hinge (4).
  10. 10. The device according to any one of claims 1 to 8, wherein the hinge (4) is provided with an observation window (44), and when the chip (1) and the glass slide (2) are buckled, the projection of the observation window (44) coincides with the projection part of the chip (1) along the thickness direction of the base (3).

Description

Space multiunit science transfer device Technical Field The utility model relates to the technical field of space multiple mathematics, in particular to a space multiple mathematics transfer device. Background Spatial transcriptomics is a rapidly developing field of biotechnology in recent years that is capable of resolving gene expression profiles while preserving the original spatial positional information of tissue samples, thereby revealing the functional heterogeneity of cells in the tissue microenvironment. At present, the development of space transcriptome to high resolution analysis and multi-group chemical combined analysis is carried out, for space multi-group chemical experiments, the tissue is usually required to be pretreated, if the tissue is directly attached to a chip and is pretreated, the high temperature and acid-base reagent treatment in the pretreatment process can influence the stability of capturing the nucleic acid sequence on the chip, and the tissue is pretreated and then transferred to the chip, so that the damage can be reduced. However, the existing space multiunit chemical transfer device is complex to operate, and has high equipment cost, so that the experimental threshold is high, and the popularization of the space transcriptome technology is affected. Disclosure of utility model The utility model aims to provide a space multi-study transfer device which aims to solve the problems of complex space multi-study transfer operation and higher equipment cost. To achieve the purpose, the utility model adopts the following technical scheme: the space multiunit science transfer device comprises a base and a hinge, wherein the base is used for bearing a chip, the hinge is used for bearing a glass slide, the hinge is provided with a rotating part, the rotating part is rotationally connected with the base so that the chip and the glass slide can be selectively buckled and arranged, a first limiting component is arranged on the base and used for limiting the relative position of the chip and the base, and a second limiting component is arranged on the hinge and used for limiting the relative position of the glass slide and the hinge. Preferably, the base is provided with a first limit groove for limiting the position of the chip, and the hinge is provided with a second limit groove for limiting the position of the glass slide. Preferably, the length direction of the first limit groove is perpendicular to the length direction of the second limit groove. Preferably, one of the base and the hinge is provided with a connecting part, the other one is provided with a connecting block corresponding to the connecting part, and the connecting part and the connecting block are selectively buckled. Preferably, the connecting portion is disposed at an end of the hinge away from the rotating portion. Preferably, the first limiting component comprises a first limiting block and a first clamping block, the first limiting block is fixedly arranged on the base, the first clamping block is slidably arranged on the base, the first limiting block and the first clamping block are respectively arranged on two sides of the chip, the second limiting component comprises a second limiting block and a second clamping block, the second limiting block is fixedly arranged on the hinge, the second clamping block is slidably arranged on the hinge, and the second limiting block and the second clamping block are respectively arranged on two sides of the glass slide. Preferably, the first clamping block is connected with a first spring so that the first clamping block and the first limiting block clamp the chip, and/or the second clamping block is connected with a second spring so that the second clamping block and the second limiting block clamp the glass slide. Preferably, the base is provided with a containing groove corresponding to the second limiting block and the second clamping block, and when the chip is attached to the glass slide, the second limiting block and the second clamping block are located in the containing groove. Preferably, the first limiting assembly is provided with at least two groups at intervals along the length direction of the base, and/or the second limiting assembly is provided with at least two groups at intervals along the length direction of the hinge. Preferably, the hinge is provided with an observation window, and when the chip and the glass slide are buckled, projection of the observation window is overlapped with projection of the chip along the thickness direction of the base. The utility model has the beneficial effects that: The space multiunit science transfer device comprises a base, a hinge, a first limiting component and a second limiting component, wherein the base is used for bearing chips, the hinge is used for bearing glass slides, the hinge is provided with a rotating part, the rotating part is rotationally connected with the base so that the chips and the glass slides c