Search

CN-224227055-U - Fungus liquid spraying device for manufacturing mouse skin bacterial infection model

CN224227055UCN 224227055 UCN224227055 UCN 224227055UCN-224227055-U

Abstract

The utility model provides a bacterial liquid spraying device for manufacturing a bacterial infection model of a mouse skin, which comprises a fixed cylinder and two supporting rods, wherein a through groove is formed in the top of the fixed cylinder, an installation groove is formed in the front end of the through groove at the top of the fixed cylinder, a fixing mechanism is arranged in the fixed cylinder, sliding grooves are formed in the two sides of the through groove at the top of the fixed cylinder, mounting plates are fixedly connected to the two ends of the top of the fixed cylinder, a motor is fixedly arranged on one side of one mounting plate, a moving mechanism is arranged between the two mounting plates, and a limiting mechanism is arranged on the two sides of the moving mechanism.

Inventors

  • YU LINGZHI
  • WEI XIAOFENG
  • KONG ZHIHAO
  • FAN CHUN

Assignees

  • 上海实验动物研究中心

Dates

Publication Date
20260512
Application Date
20250429

Claims (7)

  1. 1. The bacterial liquid spraying device for manufacturing the mouse skin bacterial infection model comprises a fixed cylinder (1) and two supporting rods (2), wherein a through groove (3) is formed in the top of the fixed cylinder (1), an installation groove (4) is formed in the top of the fixed cylinder (1) at the front end of the through groove (3), and a fixing mechanism (5) is arranged in the fixed cylinder (1); the top of the fixed cylinder (1) is provided with sliding grooves (6) at two sides of the through groove (3), two ends of the top of the fixed cylinder (1) are fixedly connected with mounting plates (7), one end of the fixed cylinder is fixedly provided with a motor (8) at one side of each mounting plate (7), a moving mechanism (9) is arranged between the two mounting plates (7), and limiting mechanisms (10) are arranged at two sides of the moving mechanism (9) between the two mounting plates (7); The front sides of the two supporting rods (2) are fixedly connected with fixing rods (11), an adjusting plate (12) is connected between the two fixing rods (11) through a rotating shaft, and a spraying assembly (13) is arranged at the top of the adjusting plate (12).
  2. 2. The fungus liquid spraying device for manufacturing a mouse skin bacterial infection model according to claim 1, wherein the fixing mechanism (5) comprises a first fixing block (501), a second fixing block (502) and a locking nut (503), the first fixing block (501) is slidably assembled at one end inside the fixing cylinder (1), the second fixing block (502) is mounted at one end far away from the first fixing block (501) inside the fixing cylinder (1), and the locking nut (503) is in threaded connection with the tops of the first fixing block (501) and the second fixing block (502).
  3. 3. The bacterial liquid spraying device for manufacturing the mouse skin bacterial infection model according to claim 1, wherein the moving mechanism (9) comprises a threaded rod (901) and a moving block (902), the threaded rod (901) is connected between the two mounting plates (7) in a rotating shaft mode, one end of the threaded rod (901) is connected with the output shaft end of the motor (8), and the outer side of one end of the threaded rod (901) is connected with the moving block (902) in a threaded mode.
  4. 4. The bacterial liquid spraying device for manufacturing a mouse skin bacterial infection model according to claim 3, wherein a connecting plate (14) is fixedly connected to the bottom of the moving block (902), an electric push rod (15) is fixedly installed at the bottom of the connecting plate (14), and the extending end of the electric push rod (15) is fixedly connected with one end of the bottom of the adjusting plate (12).
  5. 5. The fungus liquid spraying device for manufacturing a mouse skin bacterial infection model according to claim 1, wherein the limiting mechanism (10) comprises a limiting rod (1001) and limiting blocks (1002), the limiting rods (1001) are fixedly connected to two sides of the moving mechanism (9) between the two mounting plates (7), the limiting blocks (1002) are movably connected to the outer sides of one end of the limiting rod (1001) through mounting holes, one ends of the two limiting blocks (1002) are connected with the moving block (902) through connecting blocks, and the two limiting blocks (1002) are fixedly connected with the supporting rods (2) at one ends far away from the moving block (902).
  6. 6. The fungus liquid spraying device for manufacturing the mouse skin bacterial infection model according to claim 1, wherein the supporting rods (2) and the bottom ends of the fixing rods (11) are fixedly connected with rollers (16), and the rollers (16) are arranged inside the sliding grooves (6).
  7. 7. The fungus liquid spraying device for manufacturing the mouse skin bacterial infection model according to claim 1, wherein the spraying component (13) comprises a fungus liquid reservoir (1301), a first pipeline (1302), a fungus liquid spray head (1303), a baffle plate (1304), a warm air connection port (1305), a second pipeline (1306) and a warm air spray head (1307), the fungus liquid reservoir (1301) is fixedly arranged at one end of the top of the regulating plate (12), one end of the fungus liquid reservoir (1301) is connected with the first pipeline (1302), one end of the first pipeline (1302) is fixedly provided with the fungus liquid spray head (1303), and the baffle plate (1304) is fixedly arranged outside the fungus liquid spray head (1303); The bottom of the adjusting plate (12) is fixedly provided with a warm air connection port (1305) at one side far away from the electric push rod (15), a second pipeline (1306) is fixedly connected to one side of the warm air connection port (1305), and one end of the second pipeline (1306) is connected with a warm air spray head (1307).

Description

Fungus liquid spraying device for manufacturing mouse skin bacterial infection model Technical Field The utility model mainly relates to the technical field of biological medicine, in particular to a bacterial liquid spraying device for manufacturing a mouse skin bacterial infection model. Background The experimental nude mice are used as a model animal, different types of bacteria can be smeared on the skin of the model animal, different types of skin infection models are manufactured, and then the candidate medicines are used for evaluating the treatment effect of the model, namely, the model animal is applied to non-clinical evaluation of the medicines. At present, two modes of coating bacterial liquid on the skin of an experimental nude mouse are available, one mode is to grasp the experimental nude mouse by hands, absorb the bacterial liquid by a liquid transfer device, directly coat the bacterial liquid on the skin of the experimental nude mouse, then uniformly coat the bacterial liquid by a suction head, and the other mode is to grasp the experimental nude mouse by hands, dip the bacterial liquid by a sterilizing cotton swab, and smear and inoculate the bacterial liquid along the central line of the back of the nude mouse. The two modes have the defects that firstly, the manual smearing is not easy to be uniform, the difference of the bacterium liquid smeared among individuals is easy to be larger, secondly, the bacterium liquid smeared is not easy to be dried, the bacterium liquid is easy to be stuck on other mice or cage walls when the laboratory mice returned to the squirrel cage move, the accuracy and the repeatability of research results are poor, and thirdly, when each laboratory mouse is smeared, more bacterium liquid is exposed to the air, and the biological safety problem is easy to be caused. Disclosure of Invention The utility model mainly provides a bacterial liquid spraying device for manufacturing a mouse skin bacterial infection model, which is used for solving the technical problems in the background technology. The technical scheme adopted for solving the technical problems is as follows: the bacterial liquid spraying device for manufacturing the mouse skin bacterial infection model comprises a fixed cylinder and two supporting rods, wherein a through groove is formed in the top of the fixed cylinder, an installation groove is formed in the front end of the through groove in the top of the fixed cylinder, and a fixing mechanism is arranged in the fixed cylinder; The top of the fixed cylinder is provided with sliding grooves on two sides of the through groove, two ends of the top of the fixed cylinder are fixedly connected with mounting plates, one side of one mounting plate is fixedly provided with a motor, a moving mechanism is arranged between the two mounting plates, and two sides of the moving mechanism between the two mounting plates are provided with limiting mechanisms; The front sides of the two support rods are fixedly connected with fixing rods, an adjusting plate is connected between the two fixing rods through a rotating shaft, and a spraying assembly is arranged at the top of the adjusting plate; Preferably, the fixing mechanism comprises a first fixing block, a second fixing block and a locking nut, wherein one end inside the fixing cylinder is slidably provided with the first fixing block, one end, far away from the first fixing block, inside the fixing cylinder is provided with the second fixing block, and the tops of the first fixing block and the second fixing block are respectively in threaded connection with the locking nut; Preferably, the moving mechanism comprises a threaded rod and a moving block, a threaded rod is connected between the two mounting plates in a rotating shaft manner, one end of the threaded rod is connected with the output shaft end of the motor, and the outer side of one end of the threaded rod is connected with the moving block in a threaded manner; Preferably, the bottom of the moving block is fixedly connected with a connecting plate, the bottom of the connecting plate is fixedly provided with an electric push rod, and the extending end of the electric push rod is fixedly connected with one end of the bottom of the adjusting plate; Preferably, the limiting mechanism comprises a limiting rod and limiting blocks, wherein the limiting rods are fixedly connected to two sides of the moving mechanism between the two mounting plates, the outer sides of one end of the limiting rod are movably connected with the limiting blocks through mounting holes, one ends of the two limiting blocks are connected with the moving block through connecting blocks, and one ends of the two limiting blocks far away from the moving block are fixedly connected with the supporting rods; Preferably, the bottom ends of the supporting rod and the fixing rod are fixedly connected with rollers, and the rollers are arranged in the sliding grooves; Preferably, the spraying ass