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CN-224227065-U - Second generation technology target sequencing device

CN224227065UCN 224227065 UCN224227065 UCN 224227065UCN-224227065-U

Abstract

The utility model relates to the technical field of sequencing devices, in particular to a second-generation technical targeted sequencing device which comprises an equipment shell, wherein a first linear sliding rail is fixedly arranged at the upper end inside the equipment shell, a first electric telescopic rod is fixedly arranged at the lower end of the first linear sliding rail, a clamping part is fixedly arranged at the lower end of the first electric telescopic rod, an installation box and an installation box are fixedly connected to the lower end inside the equipment shell, a supporting component and a limiting component are arranged inside the installation box, a fourth electric telescopic rod is fixedly connected to the inner wall of one side of the installation box, and a push plate is fixedly connected to one end of the fourth electric telescopic rod. According to the utility model, through the arrangement of the first linear slide rail, the first electric telescopic rod and the clamping part, automatic loading and unloading of the test tube can be realized, the time required by mixing can be shortened through a compound shaking mode, the efficiency of targeted sequencing is improved, and the situation that the test tube beside the test tube to be moved is damaged due to collision is avoided through the lifting of the test tube.

Inventors

  • XU YUYAO
  • WANG LEI
  • WANG RONG
  • MAO CHUNPING
  • CAO CHUNYUAN
  • JIANG YIFAN
  • SUN CHENLIN

Assignees

  • 张家港市中医医院

Dates

Publication Date
20260512
Application Date
20250522

Claims (7)

  1. 1. The utility model provides a second generation technique target sequencing device, including equipment casing (1), a serial communication port, equipment casing (1) inside upper end fixedly provided with first straight slide rail (3), first straight slide rail (3) lower extreme fixedly provided with first electric telescopic handle (4), first electric telescopic handle (4) lower extreme fixedly provided with clamping part (5), equipment casing (1) inside lower extreme fixedly connected with mounting box (6) and mounting box (2), mounting box (6) inside is provided with supporting component (7) and spacing subassembly (12), and supporting component (7) and spacing subassembly (12) all symmetry are provided with two sets of, mounting box (6) one side inner wall fixedly connected with fourth electric telescopic handle (13), fourth electric telescopic handle (13) one end fixedly connected with push pedal (14), and push pedal (14) all are connected with two sets of spacing subassembly (12); The lower end of the inside of the installation box (2) is fixedly connected with a rubber plate (11), a limiting orifice plate (9) fixed on the inner wall of the installation box (2) is arranged above the rubber plate (11), a movable plate (10) is arranged at the upper end of the limiting orifice plate (9) in contact with the contact, five groups of movable plates (10) are arranged at intervals, five groups of movable plates (10) are all in sliding connection with the inner wall of the installation box (2), through holes matched with the positions and the sizes of the movable plates (10) and the limiting orifice plates (9) are formed in the movable plates, and lifting assemblies (8) are arranged on the inner walls of the two sides of the installation box (2).
  2. 2. The second generation technology targeted sequencing device according to claim 1, wherein the lifting assembly (8) comprises a second linear sliding table (81) fixedly connected to the inner wall of one side of the installation box (2) and a fifth electric telescopic rod (82) fixedly connected to the upper end of the second linear sliding table (81).
  3. 3. The second generation technology targeted sequencing device according to claim 1, wherein the support assembly (7) comprises a second electric telescopic rod (73) fixedly connected to the lower end inside the installation box (6), the upper end of the second electric telescopic rod (73) is fixedly connected with a support plate (72), and the upper end of the support plate (72) is slidably connected with a U-shaped installation plate (71).
  4. 4. The second generation targeted sequencing device according to claim 3, wherein the lower end of the U-shaped mounting plate (71) is fixedly connected with an embedded rod (74), a sliding strip (75) is slidably arranged at the lower end of the inside of the mounting box (6), one end of the sliding strip (75) is fixedly connected with one side of the push plate (14), and the lower end of the embedded rod (74) is movably embedded with the upper end of the sliding strip (75).
  5. 5. A second generation technology targeted sequencing device according to claim 3, wherein the limiting assembly (12) comprises two connecting rods (121) respectively rotatably connected to two sides of the U-shaped mounting plate (71), two groups of connecting rods (121) are fixedly connected with fixing plates (122) at opposite ends, a first limiting strip (123) is slidably arranged between the two groups of fixing plates (122), a second limiting strip (126) is fixedly arranged between the two groups of fixing plates (122), a motor (124) is fixedly connected to one side of the U-shaped mounting plate (71), and the output end of the motor (124) is fixedly connected with one group of connecting rods (121).
  6. 6. The second generation technology targeted sequencing device according to claim 5, wherein a third electric telescopic rod (127) is fixedly connected to one side of the second limiting rod (126), the other end of the third electric telescopic rod (127) is fixedly connected to one side of the first limiting rod (123), and two groups of the third electric telescopic rods (127) are arranged.
  7. 7. The second generation technology targeted sequencing device according to claim 6, wherein a plurality of through grooves are formed in the first limiting strip (123) and the second limiting strip (126), and anti-collision rubber strips (125) are fixedly arranged on the inner sides of the through grooves.

Description

Second generation technology target sequencing device Technical Field The utility model relates to the technical field of sequencing devices, in particular to a second-generation technology targeted sequencing device. Background Second generation technology targeted sequencing is an advanced DNA sequencing method that combines the advantages of high throughput sequencing technology and targeted capture technology. The method can carry out deep sequencing aiming at specific genome regions, thereby rapidly and accurately acquiring the genetic information of the regions. By designing specific probes or utilizing capture techniques, second generation technology targeted sequencing can selectively capture and sequence genes or gene regions of interest, avoiding the large amount of unrelated data and costs associated with whole genome sequencing. The sequencing method is widely applied to the fields of genomics research, genetic disease diagnosis, drug research and the like, provides powerful technical support for scientific research and clinical application, and needs to mix a DNA library with a hybridization solution containing a targeting probe and carry out hybridization reaction under proper temperature and time conditions in the process of targeting sequencing of a second generation technology. The probe can be specifically combined with a target region in the DNA library, so that targeted capture is realized; The Chinese patent with the publication number of CN215028270U is issued, the test tube on the test tube rack is driven to shake through the left-right reciprocating motion of the sliding rod, so that mixing is realized, however, the mixing effect through transverse shaking is poor, the time consumption is long, and the taking-out and putting-in of the test tube are required to be manually carried out, so that the efficiency of targeted sequencing is low. Disclosure of utility model The utility model aims to solve the problems in the prior art, and provides a second-generation technology targeted sequencing device. In order to achieve the aim, the second-generation technology targeted sequencing device comprises an equipment shell, wherein a first linear slide rail is fixedly arranged at the upper end inside the equipment shell, a first electric telescopic rod is fixedly arranged at the lower end of the first linear slide rail, a clamping part is fixedly arranged at the lower end inside the equipment shell, an installation box and an installation box are fixedly connected to the lower end inside the equipment shell, a supporting component and a limiting component are arranged inside the installation box, the supporting component and the limiting component are symmetrically provided with two groups, a fourth electric telescopic rod is fixedly connected to the inner wall of one side of the installation box, a push plate is fixedly connected to one end of the fourth electric telescopic rod, and the push plate is connected with the two groups of limiting components; The lower end of the inner part of the installation box is fixedly connected with a rubber plate, a limiting orifice plate fixed on the inner wall of the installation box is arranged above the rubber plate, the upper end of the limiting orifice plate is contacted with a movable plate, five groups of movable plates are arranged at intervals, five groups of movable plates are all in sliding connection with the inner wall of the installation box, through holes matched with the positions and the sizes of the movable plates and the limiting orifice plates are formed in the movable plates, and lifting assemblies are arranged on the inner walls of the two sides of the installation box. Preferably, the lifting assembly comprises a second linear sliding table fixedly connected to the inner wall of one side of the installation box and a fifth electric telescopic rod fixedly connected to the upper end of the second linear sliding table. Preferably, the support assembly comprises a second electric telescopic rod fixedly connected to the lower end of the inner portion of the installation box, the upper end of the second electric telescopic rod is fixedly connected with a support plate, and the upper end of the support plate is slidably connected with a U-shaped installation plate. Preferably, the embedded rod is fixedly connected to the lower end of the U-shaped mounting plate, the sliding bar is slidably arranged at the lower end inside the mounting box, one end of the sliding bar is fixedly connected with one side of the push plate, and the lower end of the embedded rod is movably embedded with the upper end of the sliding bar. Preferably, the spacing subassembly is including rotating two connecting rods of connection in U type mounting panel both sides respectively, two sets of the equal fixedly connected with fixed plate of the relative one end of connecting rod, two sets of the fixed plate between slide be provided with first spacing, two sets of the