CN-224231390-U - Brain section fixing device after medical science experiment mouse sacrifice

CN224231390UCN 224231390 UCN224231390 UCN 224231390UCN-224231390-U

Abstract

The utility model discloses a brain slice fixing device after the death of a medical experiment mouse, which belongs to the technical field of medical experiments, and comprises a synchronous limiting assembly, a transmission cylinder, a connecting cylinder, an auxiliary limiting assembly and a second threaded rod, wherein the synchronous limiting assembly is arranged in a placing platform, the transmission cylinder is arranged in one end of the placing platform in a limiting penetrating manner, the transmission gear is fixedly arranged at one end of the transmission cylinder, the two sides of the transmission gear are respectively engaged with a receiving gear, one ends of the receiving gears, which are close to the two sides of the placing platform, are respectively fixedly connected with the connecting cylinder, the first threaded rod is arranged in the internal thread transmission of the connecting cylinder, the auxiliary limiting assembly is arranged above the synchronous limiting assembly in a connecting manner, and the auxiliary limiting assembly is correspondingly arranged on a transmission plate.

Inventors

ZHANG DONGXIAN
LUO CHENGLIANG
ZENG XIAOFENG
WANG SHANGWEN
PENG YANXIA
LI XIONG
DING JIAMENG

Assignees

昆明医科大学

Dates

Publication Date: 20260512
Application Date: 20250527

Claims (10)

1. Brain section fixing device after medical science experiment mouse sacrifice, characterized by including Placing a platform; The brain limiting mechanism comprises a synchronous limiting assembly, the synchronous limiting assembly is arranged in the placing platform, the synchronous limiting assembly comprises a transmission barrel, the transmission barrel is arranged in one end of the placing platform in a penetrating mode in a limiting mode, a transmission gear is fixedly arranged at one end of the transmission barrel, which is positioned in the placing platform, two sides of the transmission gear are respectively engaged with a receiving gear, one end, close to two sides of the placing platform, of the receiving gear is respectively fixedly connected with a connecting barrel, internal threads of the connecting barrel are used for transmitting first screws, and transmission plates are connected to the outer portion of the first screws in a transmission mode; The upper part of the synchronous limiting assembly is connected with an auxiliary limiting assembly, and the auxiliary limiting assembly is correspondingly arranged on the transmission plate.
2. The brain slice fixing device after the medical experiment mice are killed according to claim 1, wherein the synchronous limiting assembly further comprises a transmission rod fixedly connected to one end, far away from the transmission cylinder, of the transmission gear, a plurality of extension gears are sleeved on the outer portion of the transmission rod in an equally dividing mode, receiving gears are arranged on two sides of the extension gears in a meshed transmission mode respectively, and connecting cylinders are fixedly connected to one ends, close to two sides of the placement platform, of the receiving gears respectively.
3. The brain slice fixing device after the medical experiment mice are killed according to claim 2, wherein the end parts of the connecting cylinders are respectively limited to rotate to penetrate through two sides of the placing platform, and the transmission gear, the receiving gear and the receiving gear are bevel gears.
4. The brain slice fixing device after the medical experiment mice are killed according to claim 2, wherein one end of the first screw rod is inserted into the connecting cylinder in a threaded mode, a limiting rod is inserted into the outer side of the end face of the other end of the first screw rod in a sliding mode, a plurality of groups of limiting rods are arranged in an evenly encircling mode, and the other ends of the plurality of groups of limiting rods are fixedly connected with the inner side of the transmission plate.
5. The brain slice fixing device after the medical experiment mice are killed according to claim 4, wherein the auxiliary limiting assembly comprises a second threaded rod, the second threaded rod is in threaded transmission with the first threaded rod, the second threaded rod penetrates through the transmission plate, the bottom of the transmission plate is fixedly connected with a bottom plate, and the bottom plate is arranged at the bottom of the placement platform in a limiting sliding embedded mode.
6. The brain slice fixing device after the medical laboratory mouse is killed according to claim 5, wherein a handle is fixedly connected to the outer end of the second threaded rod, and the handle is located on the outer side of the transmission plate.
7. The brain slice fixing device after the medical experiment mice are killed according to claim 5, wherein the top of the transmission plate is fixedly connected with limiting shells respectively, an elastic block is arranged on the limiting shells near the middle of one end of the placing platform in a limiting sliding mode, a pushing plate is fixedly connected to the outer end portion of the elastic block, and the pushing plate is in limiting abutting connection with the brains of the mice.
8. The brain slice fixing device after the medical experiment mice are killed according to claim 7, wherein the two sides of the elastic block, which are positioned at one end inside the limiting shell, are respectively provided with a bump, the elastic block is matched with the bumps to slide in the limiting shell in a limiting way, and a spring is arranged between the elastic block and the inside of the limiting shell.
9. The brain slice fixing device after the medical experiment mice are killed according to claim 8, wherein a silica gel sleeve is sleeved outside the push plate.
10. The brain slice fixing device after the medical laboratory mouse is killed according to claim 8, wherein a pressure sensor is arranged in the elastic block and is abutted with the spring.

Description

Brain section fixing device after medical science experiment mouse sacrifice Technical Field The utility model relates to the field of medical experiments, in particular to a brain slice fixing device after a medical experiment mouse is sacrificed. Background In the field of medical science, the section analysis of the brain of an experimental mouse is an important means for exploring the nerve structure and pathological mechanism. However, the existing mouse brain slice fixing device is difficult to realize uniform and stable clamping of the mouse brain, lack of synchronism of movement among different clamping components easily causes uneven stress of the mouse brain in the fixing process, tissue deformation is caused, slice quality is affected, on the other hand, due to irregular shape of the mouse brain, a single fixing mode cannot adapt to complex forms of the mouse brain, fixing effect is poor, even the situation of sliding and offset of brain tissue occurs in the slicing process, and accuracy and repeatability of experiments are reduced. In addition, the existing devices mostly adopt a rigid fixing mode, lack flexible protection on brain tissues, and are easy to damage fragile nerve tissues. How to invent a brain slice fixing device after the medical experiment mice are killed to improve the problems becomes a problem to be solved urgently by the person skilled in the art. Disclosure of utility model In order to make up for the defects, the utility model provides a brain slice fixing device after the mice in medical experiments are killed, and aims to solve the problem that the existing mouse brain slice fixing device is difficult to realize uniform and stable clamping of the brains of the mice. The utility model is realized by a brain slice fixing device after the mice in medical experiments are killed, which comprises The brain limiting mechanism comprises a synchronous limiting assembly, wherein the synchronous limiting assembly is arranged in the placing platform, the synchronous limiting assembly comprises a transmission cylinder, the transmission cylinder is arranged in one end of the placing platform in a penetrating manner in a limiting manner, a transmission gear is fixedly arranged at one end of the transmission cylinder, which is positioned in the placing platform, two sides of the transmission gear are respectively engaged with a receiving gear, one ends, close to two sides of the placing platform, of the receiving gear are respectively fixedly connected with a connecting cylinder, the internal thread transmission of the connecting cylinder is provided with a first screw rod, and the external transmission of the first screw rod is connected with a transmission plate; The upper part of the synchronous limiting assembly is connected with an auxiliary limiting assembly, and the auxiliary limiting assembly is correspondingly arranged on the transmission plate. In a preferred technical scheme of the utility model, the synchronous limiting assembly further comprises a transmission rod, the transmission rod is fixedly connected to one end, far away from the transmission cylinder, of the transmission gear, a plurality of extension gears are sleeved at equal intervals on the outer part of the transmission rod, receiving gears are respectively arranged on two sides of the extension gears in a meshed transmission mode, and connecting cylinders are respectively fixedly connected to one ends, close to two sides of the placement platform, of the receiving gears. In a preferred technical scheme of the utility model, the end parts of the connecting cylinders respectively limit and rotate to penetrate through two sides of the placing platform, and the transmission gear, the receiving gear and the receiving gear are bevel gears. In a preferred technical scheme of the utility model, one end of the first screw rod is inserted into the connecting cylinder in a threaded manner, a limiting rod is inserted into the outer side of the end face of the other end of the first screw rod in a sliding manner, a plurality of groups of limiting rods are arranged in an evenly-divided and encircling manner, and the other ends of the plurality of groups of limiting rods are fixedly connected with the inner side of the transmission plate. In a preferred technical scheme of the utility model, the auxiliary limiting assembly comprises a second threaded rod, the second threaded rod is in threaded transmission with the first threaded rod, the second threaded rod penetrates through the transmission plate, the bottom of the transmission plate is fixedly connected with a bottom plate, and the bottom plate is in limiting sliding embedded arrangement at the bottom of the placement platform. In a preferred embodiment of the present utility model, a handle is fixedly connected to the outer end of the second threaded rod, and the handle is located at the outer side of the transmission plate. In a preferred technical scheme of the utility