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EP-3862008-B1 - ADHESIVE SHEET FOR AFFIXATION TO BODY, HOUSED IN CONTAINER

EP3862008B1EP 3862008 B1EP3862008 B1EP 3862008B1EP-3862008-B1

Inventors

  • KIMURA, SHOHEI

Dates

Publication Date
20260506
Application Date
20190925

Claims (14)

  1. An adhesive sheet for affixation to the body wherein the adhesive sheet is sealed in a low gas-permeable container, the adhesive sheet comprising the following components (A) and (B): (A) bubbles containing carbon dioxide gas in a bubble fraction of 10% or more and 40% or less, and (B) water, wherein the total area occupied by bubbles having an imaginary diameter of 5 mm or more is 10% or less, in 100% of the surface area of the adhesive sheet for affixation to the body, a content of carbon dioxide gas in the total amount of the adhesive sheet for affixation to the body is from 100 to 20,000 ppm, and wherein the adhesive sheet is a sheet composed of an aqueous gel layer supported on a support layer, wherein a content of carbon dioxide gas is from 30 to 90% by mass in 100% by mass in total of the gas present in the low gas-permeable container, wherein low gas-permeable means a carbon dioxide gas transmission rate of 50 cc/m 2 ·day·atm or less as determined by ASTM D-1434; wherein, bubble fraction is the value measured within 5 minutes after opening the container and taking the sheet out from the container, wherein the bubble fraction is measured according to the following Equation (1): Bubble fraction % = A − B / A × 100 in Equation (1), A is the volume (mL) of the sheet from the length, width, and height thereof, B is the weight (g)of the sheet, wherein, the total area occupied by bubbles having an imaginary diameter of 5 mm or more is 10% or less is the value measured within 5 minutes after opening the container and taking out the sheet at room temperature of 25°C and relative humidity of 50%, wherein the total area occupied by bubbles having an imaginary diameter of 5 mm or more refers to the sum obtained by selecting all the bubbles having an imaginary diameter of 5 mm or more and present on the surface of the side of the predetermined sheet which is in contact with the skin, and calculating the area of the imaginary circle based on the imaginary diameter, then the value of the total area is divided by the surface area of the predetermined sheet which is determined as 100% to determine the value of the total area occupied by bubbles having an imaginary diameter of 5 mm or more in 100% of the surface area of the adhesive sheet for affixation to the body (%), wherein the imaginary diameter of the bubble is the value obtained by adding the long diameter to the short diameter thereof, followed by dividing by 2, and wherein, the imaginary circle is the circle whose diameter is the value obtained by adding the long diameter to the short diameter thereof, followed by dividing by 2.
  2. The adhesive sheet for affixation to the body according to claim 1, comprising the bubbles containing carbon dioxide gas of component (A) in a bubble fraction of 15% or more and 38% or less.
  3. The adhesive sheet for affixation to the body according to claim 1 or 2, wherein the total area occupied by bubbles having an imaginary diameter of 5 mm or more is 5% or less, in 100% of the surface area of the adhesive sheet for affixation to the body.
  4. The adhesive sheet for affixation to the body according to any one of claims 1 to 3, wherein the content of the water of component (B) is from 60 to 95% by mass in 100% by mass in total of the adhesive sheet for affixation to the body.
  5. The adhesive sheet for affixation to the body according to any one of claims 1 to 4, wherein the adhesive sheet is a sheet composed of an aqueous gel layer supported on a support layer and a release layer.
  6. The adhesive sheet for affixation to the body according to claim 5, wherein the aqueous gel layer comprises a cross-link structure formed by an anionic polymer, a crosslinking agent, and water.
  7. The adhesive sheet for affixation to the body according to claim 6, wherein the anionic polymer is a polymer having a carboxyl group, a sulfate group, or a phosphate group.
  8. The adhesive sheet for affixation to the body according to any one of claims 5 to 7, the thickness of the support layer is from 0.05 to 2.0 mm.
  9. The adhesive sheet for affixation to the body according to any one of claims 5 to 8, wherein the support layer is one or two or more selected from the group consisting of woven fabric, non-woven fabric, knitted fabric, synthetic resin film, and waterproof paper.
  10. The adhesive sheet for affixation to the body housed in a container according to any one of claims 1 to 9, wherein a content of carbon dioxide gas is from 60 to 90% by mass in 100% by mass in total of the gas present in the low gas-permeable container.
  11. The adhesive sheet for affixation to the body according to any one of claims 1 to 10, wherein a content of carbon dioxide gas in the total amount of the adhesive sheet for affixation to the body is from 200 to 10,000 ppm.
  12. The adhesive sheet for affixation to the body according to any one of claims 1 to 11, wherein the thickness is from 0.5 to 3 mm.
  13. A method for producing the adhesive sheet for affixation to the body according to any one of claims 5 to 12, comprising the following steps (I) to (III): (I) a step of mixing gel layer-forming components and water (B) to prepare an aqueous gel containing bubbles; (II) a step of spreading the obtained aqueous gel on a support by a coater through which a support layer is inserted to form an aqueous gel layer supported on the support layer and containing the bubbles; and (III) a step of accommodating, in a low gas-permeable container, a sheet comprising the aqueous gel layer supported on the support layer and containing the bubbles, and then injecting carbon dioxide gas into and sealing the container, allowing incorporation of bubbles containing carbon dioxide gas (A).
  14. The method for producing the adhesive sheet for affixation to the body according to claim 13, wherein the coater used in step (II) is a roll coater.

Description

Field of the Invention The present invention relates to an adhesive sheet for affixation to the body housed in a container. Background of the Invention Performing standing work or desk work for a long period of time may cause fatigue, lassitude, swelling, pain, and the like on each part of the body. Promotion of blood circulation by massage, stretching, bathing, and the like is widely known to be effective to eliminate these symptoms. For example, Patent Literature 1 discloses a swelling ameliorant consisting of a composition containing a carbon dioxide gas generating agent in an amount such that the carbon dioxide gas concentration in the hot water can be 60 ppm or more, and it is described that the carbon dioxide gas generating agent has a very high effect of ameliorating swelling in a short time, by acting carbon dioxide gas which enlarges capillary vessels under the conditions of high hydrostatic pressure. It is also known that, even when no hydraulic pressure is applied on the body like bathing, the action of carbon dioxide gas on the skin promotes the blood circulation of the skin, and various carbon dioxide gases utilizing this action or cosmetics and the like into which a carbon dioxide gas generating material is blended have been investigated. For example, Patent Literature 2 discloses an effervescent skin blood circulation promoting coating agent containing hydrocarbon, carbon dioxide, and an emulsifying agent. Patent Literature 3 discloses a sheet for affixation to the body housed in a container in which a laminated sheet of a bubble gel layer or a bubble liquid layer which contains bubbles having a bubble fraction of from 5 to 50% and a resin film is sealed in a low gas-permeable container, wherein the sheet contains 30% by mass or more of gas having biological activities to the body in a space portion of the container during storage. (Patent Literature 1) JP-A-2005-314298(Patent Literature 2) JP-A-2005-2046(Patent Literature 3) JP-A-2010-202609 Summary of the Invention The present invention relates to an adhesive sheet according to the claims for affixation to the body housed in a container, containing the following components (A) and (B): (A) bubbles containing carbon dioxide gas in a bubble fraction of 10% or more and 40% or less, and(B) water, wherein the total area occupied by bubbles having an imaginary diameter of 5 mm or more is 10% or less, in 100% of the surface area of the adhesive sheet for affixation to the body,a content of carbon dioxide gas in the total amount of the adhesive sheet for affixation to the body is from 100 to 20,000 ppm,the adhesive sheet for affixation to the body is sealed in a low gas-permeable container, wherein the adhesive sheet is a sheet composed of an aqueous gel layer supported on a support layer, and wherein a content of carbon dioxide gas is from 30 to 90% by mass in 100% by mass in total of the gas present in the low gas-permeable container. The swelling ameliorant described in Patent Literature 1 described above needs to continuously maintain thermal and high hydrostatic pressure conditions for 5 minutes or more, and thus, the use situation is limited and it lacks in easiness. In addition, although the agent and the sheet described in Patent Literatures 2 and 3 utilize the blood circulation promoting effect by carbon dioxide gas, carbon dioxide gas is rapidly released to the atmosphere or metabolized in vivo after application to the body, and thus, the persistence of the increase in blood flow after application needs to be further increased, in order to ameliorate symptoms such as fatigue, lassitude, swelling, and pain of the body. Among them, it was revealed by the present inventor that, when the sheet described in Patent Literature 3 is used for large parts in the body or parts with intense movement such as the foot, affixability and conformability to the body may be deteriorated. That is, the present invention relates to an adhesive sheet for affixation to the body which is excellent in enhancement and persistence of the blood circulation promoting action, has high affixability and conformability as a sheet, and is easily and widely applicable to the body in any use situation. Then, as a result of intensive studies to solve the above problems, the present inventor found that an adhesive sheet for affixation to the body which can enhance and persist the blood circulation promoting action for a long period of time while effectively increasing affixability and conformability as a sheet can be obtained by controlling the bubble fraction and the size of bubbles to a specific range while containing a specific amount of carbon dioxide gas. By containing a specific amount of carbon dioxide gas as bubbles of specific conditions, the adhesive sheet for affixation to the body housed in a container of the present invention effectively increases affixability and conformability while retaining favorable smoothness as a sheet, and exerts excellent effects thereof