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EP-4057052-B1 - OPHTHALMIC SET FOR MYOPIA PROGRESSION CONTROL

EP4057052B1EP 4057052 B1EP4057052 B1EP 4057052B1EP-4057052-B1

Inventors

  • BARANTON, KONOGAN
  • VILLETTE, THIERRY
  • Barrau, Coralie
  • GUILLOT, MATTHIEU

Dates

Publication Date
20260506
Application Date
20210308

Claims (12)

  1. An ophthalmic set for myopia progression control, comprising spectral filtering means arranged for being effective on light that enters a user's eye, said spectral filtering means being such that the ophthalmic set has a vision transmission value higher than 70% when assessed with CIE Standard Illuminant D65, and an average transmission value assessed over the spectral range from 460 nm to 510 nm that is less than 30%.
  2. The ophthalmic set of claim 1, wherein the spectral filtering means are further such that the ophthalmic set has another average transmission value assessed over the other spectral range from 560 nm to 600 nm, that is equal to or less or equal than 70%, preferably less than 50%.
  3. The ophthalmic set of claim 1 or 2, further comprising wavefront modifying means adapted to modify wavefronts of the light that enters the user's eye for slowing down, by an own efficiency of said wavefront modifying means, the myopia progression of the user, the wavefront modifying means being combined with the spectral filtering means within the ophthalmic set so that the spectral filtering means and the wavefront modifying means are effective simultaneously on the light that enters the user's eye, whereby respective efficiencies of the wavefront modifying means and spectral filtering means for slowing-down myopia progression are combined for the user of the ophthalmic set.
  4. The ophthalmic set of claim 3, wherein the wavefront modifying means comprise one of the following: /i/ a spectacle lens (1, 2) or contact lens provided with microlenses (21) designed for focusing part of the light that enters the user's eye at a distance in front of a user's retina; /ii/ a spectacle lens (1, 2) or contact lens provided with non-spherical microlenses designed for producing light volumes at a distance in front of a user's retina from part of the light that enters the user's eye; /iii/ a spectacle lens (1, 2) or contact lens provided with light-diffusing elements (31); /iv/ a spectacle lens (1, 2) or contact lens of progression addition type or bifocal prismatic type; or /v/ a spectacle lens or contact lens adapted for correcting myopia, and the ophthalmic set further comprising an atropine amount to be administered to the user so as to be effective when the user is equipped with the wavefront modifying means combined with the spectral filtering means.
  5. The ophthalmic set of claim 3 or 4, wherein the wavefront modifying means comprise light-diffusing elements (31), and the ophthalmic set has one of the following arrangements: - the spectral filtering means are located on a side of the light-diffusing elements (31) that is opposite the user, when said ophthalmic set is used; or - the spectral filtering means are superposed with the light-diffusing elements (31) within a common layer.
  6. The ophthalmic set of claim 3 or 4, wherein the wavefront modifying means comprise microlenses (21), said microlenses being of refractive type, in particular unifocal or bifocal refractive-type microlenses, or diffractive type, in particular pi-Fresnel microlenses.
  7. The ophthalmic set of any one of claims 3 to 6, wherein the wavefront modifying means comprise a spectacle lens, and the spectral filtering means comprise one among: - at least one optical filter of interferential type, located on a face of a base element of the spectacle lens; - a dye composition that is included in a base element of the spectacle lens; - a dye composition that is included in a film adhered on a base element of the spectacle lens; - a patch suitable for being affixed, preferably in a releasable manner, to the spectacle lens; or - a clip-on element to be affixed, preferably in a releasable manner, to a spectacle frame which accommodates the spectacle lens.
  8. The ophthalmic set of any one of claims 3 to 6, wherein the wavefront modifying means comprise a contact lens, and the spectral filtering means comprise one among: - a spectacle lens to be worn by the user simultaneously to the contact lens; or - a dye composition that is included in a base element of the contact lens.
  9. The ophthalmic set of any one of claims 1 to 8, further comprising at least one among: - alert means adapted for informing the user to equip himself with the spectral filtering means, or with the spectral filtering means combined with the wavefront modifying means, at a fixed period before bedtime; and - light-measurement means (5) adapted for measuring an intensity of ambient light, and alert means coupled to the light-measurement means and adapted for informing the user to equip himself with the spectral filtering means, or with the spectral filtering means combined with the wavefront modifying means, when the intensity of ambient light becomes less than a threshold.
  10. The ophthalmic set of claim 9, comprising the alert means adapted for informing the user to equip himself with the spectral filtering means, or with the spectral filtering means combined with the wavefront modifying means, at the fixed period before a determined expected bedtime, said fixed period being comprised between 1 hour and 6 hours, preferably comprised between 2 hours and 4 hours.
  11. The ophthalmic set of claim 9, comprising the light-measurement means (5) adapted for measuring the intensity of ambient light, and the alert means coupled to the light-measurement means and adapted for informing the user to equip himself with the spectral filtering means, or with the spectral filtering means combined with the wavefront modifying means, when the intensity of ambient light becomes less than the threshold, said threshold being comprised between 300 Lux and 1000 Lux.
  12. The ophthalmic set of any one of claims 1 to 8, wherein the spectral filtering means are electrochromic means capable of switching between a blue-blocking state where the average transmission value of the ophthalmic set, assessed over the spectral range from 460 nm to 510 nm, or 440 nm to 520 nm, is equal to or less than 50%, and a clear state where said average transmission value is higher than 50%, and the ophthalmic set further comprises light-measurement means (5) adapted for measuring an intensity of ambient light, and control means coupled to the light-measurement means and arranged for switching the electrochromic means into the blue-blocking state when the intensity of ambient light becomes less than a threshold.

Description

The invention relates to an ophthalmic set for myopia progression control. In the present description, the phrases myopia progression control, myopia progression slowing-down and myopia progression reduction are used with equivalent meanings. -- BACKGROUND OF THE INVENTION -- Myopia progression has been established through many observations and well documented for several years, although its cause(s) is (are) still subject to doubts and research. Myopia progression is the fact that for one person, his/her myopia increases with time at a rate which almost did not exist before. Kids are the most concerned with myopia progression, and it is thus a major issue for humanity to address this problem. Artificial light, in particular that produced by screens or LEDs, is suspected as being a cause for myopia progression, but the actual biological phenomena and mechanisms which lead to myopia progression remain at hypothesis level. Several principles and methods have already been proposed for myopia progression control, including those now mentioned. One of these methods consists in adding to spectacle lenses or contact lenses used for correcting myopia microlenses that focus part of light at a distance in front of the retina, in addition to the light that is focused on the retina for allowing sharp vision to the wearer who is equipped with these spectacle or contact lenses. Another method consists in adding to the spectacle lenses or contact lenses used for correcting myopia aspherical microlenses that produce light volumes at a distance in front of the retina, again in addition to the light that is focused on the retina for producing the sharp image. Still another method consists in adding to the spectacle lenses or contact lenses used for correcting myopia diffusing elements which reduce the vision contrast of the wearer. Still other methods implement progressive addition lenses which provide power addition to compensate for the lag of accommodation, or bifocal prismatic lenses for producing both the power addition and a prism effect. All these methods are based on lenses that are designed for modifying wavefronts of the light that enters the eyes of the wearer, or modifying wavefronts of part of this light. Further methods are based on other principles, such as administering atropine to the subject, or wearing rigid contact lenses during nights for modifying the shape of the cornea. But all these methods turn out not to be efficient enough in many cases for myopia progression control, so that new solutions are still required or even combinations of solutions. Studies have been performed recently that suggest a role of the choroid in myopia progression. A thinning of the choroid is associated with a long-term length increase of the eyeball, which leads to myopia increase. In addition, it has been recently observed that light may enhance choroid thinning. This would be due to biological circadian cycles, either local in the eyes or central for the person or even both. The wavelength range from 440 nm (nanometer) to 520 nm, corresponding to blue-green colours, is the one implied in central circadian regulation (with melanopsin absorption peaking at 480 nm) and is suspected playing a role for myopia progression. Another spectral range, from 560 nm to 600 nm and corresponding to amber light, also seems to play a role with myopia progression, but in a lesser extent compared to blue-green light. Filters of the prior art are disclosed in WO 2019/238648 A1. Starting from this situation, one object of the present invention consists in providing new means for allowing myopia progression control, which are more efficient than those known from prior art. Another object of the invention is that such means are easy for the user, without causing vision discomfort. -- SUMMARY OF THE INVENTION -- For meeting at least one of these objects or others, a first aspect of the present invention proposes an ophthalmic set for myopia progression control, which comprises spectral filtering means arranged for being effective on light that enters a user's eye, these spectral filtering means being such that the ophthalmic set has a vision transmission value higher than 70% when assessed with CIE Standard Illuminant D65, and an average transmission value assessed over the spectral range from 460 nm to 510 nm, that is less than 30%, whereby the spectral filtering means are efficient for slowing-down a myopia progression of the user. The ophthalmic set of the invention being based on spectral filtering capability, it operates in a way different than the devices known from prior art for controlling myopia progression. Indeed, the invention ophthalmic set addresses directly the amount of light that plays a role in myopia progression instead of modifying focus features of this light. In a known manner, the vision transmission value commonly referred to as Tv takes into account spectral sensitivity features of the human eye, in addition to spectral fe