EP-4114330-B1 - SENSOR INTEGRATED DRESSINGS AND SYSTEMS

Inventors

• FISHER, Adam, John
• GOWANS, Philip
• MCKINLAY, Daniel, Stewart
• PARTINGTON, Lee, Ian
• PHILLIPS, Marcus, Damian
• QUINTANAR, FELIX, CLARENCE
• STRACHAN, Kirsty, Margaret

Dates

Publication Date

20260506

Application Date

20210304

Claims (17)

1. A method for coating a wound dressing, the method comprising: applying a first coating on a first side of a substantially flexible substrate of the wound dressing, the first side of the substrate supporting a plurality of electronic components including one or more sensors, electronic tracks, and a plurality of connectors between the electronic components and electronic tracks, wherein the first coating is applied to at least one connector of the plurality of connectors or to at least one electronic components of the plurality of electronic components to reinforce the at least one connector or the at least one electronic components; applying a second coating on the first side of the substrate, wherein the second coating comprises a first layer and a second layer, wherein the first layer is applied in a first direction and the second layer is applied in a second direction that is transverse to the first direction; and coating a second side of the substrate opposite the first side with a third coating.
2. The method of claim 1, further comprising coating at least some of the plurality of the electronic components with a fourth coating.
3. The method of claim 1 or claim 2, further comprising a plurality of perforations formed through the second coating and the substrate, the plurality of perforations configured to facilitate passage of fluid.
4. The method of any one of the preceding claims, wherein the third coating comprises the same material as that of the second coating applied to the first side of the substrate.
5. The method of any one of the preceding claims, wherein the third coating comprises a different material from that of the second coating applied to the first side of the substrate.
6. The method of any one of the preceding claims, wherein the plurality of electronic components comprise a plurality of sensors configured to obtain measurements of the wound, at least some of the plurality of sensors interconnected by a plurality of electronic connections.
7. A method for coating a wound dressing, the method comprising: applying a primer treatment layer to a first side of a substantially flexible substrate of the wound dressing; applying a first coating over the primer treatment layer on the first side of the substantially flexible substrate of the wound dressing, the first side of the substrate supporting a plurality of electronic components including one or more sensors, electronic tracks, and a plurality of connectors between the electronic components and electronic tracks, wherein the first coating is applied to at least one connector of the plurality of connectors or to at least one electronic components of the plurality of electronic components to reinforce the at least one connector or the at least one electronic components; applying a second coating on the first side of the substrate; and coating a second side of the substrate opposite the first side with a third coating.
8. The method of claim 7, further comprising applying a second primer treatment layer to a second side of the substrate prior to applying the third coating.
9. The method of claim 7 or claim 8, wherein the first primer treatment layer or the second primer treatment layer comprises parylene.
10. The method of claim 7 or claim 8, wherein the first primer treatment layer or the second primer treatment layer comprises Parylene C.
11. A wound dressing apparatus comprising: a substantially flexible substrate comprising a first side of the substrate supporting a plurality of electronic components including one or more sensors, electronic tracks, and a plurality of connectors between the electronic components and electronic tracks; a primer treatment layer on the first side of the substantially flexible substrate of the wound dressing; a first coating on the first side of the substrate applied to the primer treatment layer and over regions of at least one connector of the plurality of connectors or to at least one electronic components of the plurality of electronic components to reinforce the at least one connector or the at least one electronic components; a second coating on the first side of the substrate; and a third coating on a second side of the substrate opposite the first side.
12. The dressing of claim 11, further comprising a second primer treatment layer is applied to the second side of the substrate between the substrate and the third coating.
13. The dressing of claim 11 or claim 12, wherein the first primer treatment layer or the second primer treatment layer comprises parylene.
14. The dressing of any one of claims 11 to 13, wherein the first primer treatment layer or the second primer treatment layer comprises Parylene C.
15. The dressing of any one of claims 11 to 14, further comprising at least some of the plurality of the electronic components coated with a fourth coating.
16. The dressing of any one of claims 11 to 15, further comprising a plurality of perforations formed through the second coating and the substrate, the plurality of perforations configured to facilitate passage of fluid.
17. The dressing of any one of claims 11 to 16, wherein the plurality of electronic components comprise a plurality of sensors configured to obtain measurements of the wound, at least some of the plurality of sensors interconnected by a plurality of electronic connections.

Description

BACKGROUND Field Embodiments of the present disclosure relate to apparatuses, systems, and methods for the monitoring and/or treatment of tissue with sensor integrated or sensor-enabled dressings. Description of the Related Art Nearly all areas of medicine may benefit from improved information regarding the state of the tissue, organ, or system to be treated, particularly if such information is gathered in real-time during treatment, many types of treatments are still routinely performed without the use of sensor data collection. Instead, such treatments rely upon visual inspection by a caregiver or other limited means rather than quantitative sensor data. For example, in the case of wound treatment via dressings and/or negative pressure wound therapy, data collection is generally limited to visual inspection by a caregiver and often the underlying wounded tissue may be obscured by bandages or other visual impediments. Even intact, unwounded skin may have underlying damage that is not visible to the naked eye, such as a compromised vascular or deeper tissue damage that may lead to an ulcer or injury. Similar to wound treatment, during orthopedic treatments requiring the immobilization of a limb with a cast or other encasement, only limited information is gathered on the underlying tissue. In instances of internal tissue repair, such as a bone plate, continued direct sensor-driven data collection is not performed. Further, braces and/or sleeves used to support musculoskeletal function do not monitor the functions of the underlying muscles or the movement of the limbs. Outside of direct treatments, common hospital room items such as beds and blankets could be improved by adding capability to monitor patient parameters. Therefore, there is a need for improved sensor monitoring, particularly through the use of sensor integrated substrates which can be incorporated into existing treatment regimes. WO2020/043806 relates to devices and methods for encapsulating a portion of a wound dressing with a biocompatible coating. WO2020/157103 relates to a wound dressing including a substantially flexible substrate with a first, wound-facing side supporting a plurality of electronic components and a second side opposite the first side, a wicking layer in contact with the second side of the substrate. WO2019/096828 relates to a wound monitoring and/or therapy system which can include a substantially stretchable substrate supporting a plurality of electronic components, including sensors, and a plurality of electronic connections that connect at least some of the electronic components. SUMMARY In some cases, a wound dressing and a method for coating a wound dressing is provided. A coating may be applied on a first side of a substantially flexible substrate of the wound dressing. The first side of the substrate may support a plurality of electronic components including one or more sensors, electronic tracks, and a plurality of connectors between the electronic components and electronic tracks. The coating may be applied to the substrate, the electronic tracks, the at least one connector of the plurality of connectors, or to at least one electronic components of the plurality of electronic components to encapsulate the dressing and/or to reinforce the at least one connector or the at least one electronic components. The wound dressing and/or method of any preceding paragraph and/or any of the wound dressing and/or methods disclosed herein may further comprise one or more of the following features. The coating can be a first coating applied to the at least one connector of the plurality of connectors or to at least one electronic components of the plurality of electronic components to reinforce the at least one connector or the at least one electronic components. A second coating may be applied on the first side of the substrate, wherein the second coating comprises a first layer and a second layer, wherein the first layer is applied in a first direction and a second coating is applied in a second direction that is transverse to the first direction. A second side of the substrate opposite the first side may be coated with a third coating. The method of any preceding paragraphs and/or any of the methods disclosed herein can include one or more of the following features. The method can further comprise coating at least some of the plurality of the electronic components with a fourth coating. The method can further comprise a plurality of perforations formed through the second coating and the substrate, the plurality of perforations configured to facilitate passage of fluid. The third coating can comprise the same material as that of the second coating applied to the first side of the substrate. The third coating can comprise a different material from that of the second coating applied to the first side of the substrate. The plurality of electronic components can comprise a plurality of sensors configured to obtain measurements of