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EP-4403982-B1 - INTRAOCULAR LENSES FOR REDUCING NEGATIVE DYSPHOTOPSIA

EP4403982B1EP 4403982 B1EP4403982 B1EP 4403982B1EP-4403982-B1

Inventors

  • ROSEN, ROBERT
  • ZONNEVELD, Robin
  • ALARCON HEREDIA, Aixa
  • MEIJER, SIEGER
  • STATE, Mihai
  • CANOVAS VIDAL, CARMEN

Dates

Publication Date
20260513
Application Date
20191021

Claims (7)

  1. An intraocular lens, comprising: an optic (200) including: an anterior surface (202) defining an anterior side of the optic, and a posterior surface (204) defining a posterior side of the optic, wherein the posterior surface opposes the anterior surface; a central optical zone (225) disposed about the optical axis; and an attenuation optical zone (220) disposed about the central optical zone, wherein the attenuation optical zone is contiguous with the central optical zone, and wherein optical power of the intraocular lens is gradually reduced within the attenuation optical zone; wherein optical power of the intraocular lens is gradually reduced to zero at an outermost edge of the attenuation optical zone.
  2. The intraocular lens of claim 1, wherein a transition between the central optical zone and the attenuation optical zone is smooth and continuous.
  3. The intraocular lens of claim 2, wherein a slope of the optic is the same at a beginning of the attenuation optical zone and an end of the central optical zone.
  4. The intraocular lens of any one of claims 1-3, wherein the attenuation optical zone increases a diameter of the optic by between about 0.5 millimeter (mm) and about 3 mm.
  5. The intraocular lens of claim 4, wherein the diameter of the optic is between about 6 mm and about 8 mm.
  6. The intraocular lens of any one of claims 1-5, wherein the optic defines an edge (210), and wherein an angle of the edge is 90 degrees.
  7. The intraocular lens of any one of claims 1-5, wherein the optic defines an edge (210), and wherein an angle of the edge is less than 90 degrees.

Description

BACKGROUND Negative dysphotopsia (ND) is characterized by subjective reports and complaints from patients having an intraocular lens (IOL) implanted, where the complaints describe the presence of a dark shadow in the far periphery. A number of patient factors, including small photopic pupil, high angle kappa and hyperopia, have been identified as increasing the risk of ND. The presence of ND is likely caused by absence of light in the retinal interval between light passing through and refracted by the IOL (e.g., at lower angles of incidence) and rays missing the IOL (e.g., at higher angles of incidence). While the light passing the IOL at the lower angles of incidence is refracted, changing its direction to a lower angle, the light at the higher angles miss the IOL and continue straight without deviation, thereby creating an angular interval on the retina that is not illuminated. The problem is partially alleviated at larger pupil sizes, since optical errors create larger deviations of rays at the pupil edge which partially hits the obscured part of the peripheral retina. On the other hand, for smaller pupils the pinhole effect exacerbates the ND effect. For the natural crystalline lens, ND is not a problem, since no light will miss the lens as it is larger and closer to the pupil. Currently, there are no IOLs on the market designed to prevent ND. Posterior capsule opacification (PCO) results from lens fibers formed in the equatorial zone that migrate over the posterior side of an IOL, which can result in reduced visual quality and potentially requires a secondary intervention with an NdYAG laser. While results vary, and improved IOL designs have substantially reduced the rate of PCO the last few decades, it is still a significant issue negatively affecting the results of cataract surgery. The current state of the art for PCO prevention is a PCO edge covering the full IOL (360 degrees) with an angle of around 90-110 degrees, including on the haptics. The disclosure of WO2010/100523A1 provides an intraocular lens that includes an optic having a clear aperture having an outer diameter. The optic has opposing first and second surfaces disposed about an optical axis, the first surface including a cross- sectional profile. The optic further includes central and outer zones that fill the entire clear aperture of the optic. The central zone is disposed about the optical axis having an outer diameter, the profile in the vicinity of the central zone having a constant radius of curvature or a radius of curvature that increases with increasing radius from the optical axis. The outer zone is disposed about the central zone, the profile in the outer zone having a base curvature with a base radius of curvature and a center of curvature, the profile in the outer zone characterized in that, as the distance from the optical axis increases, the distance from the center of curvature of the base curvature also increases. US2005/041203A1 provides an ophthalmic lens that includes an optical zone having a center and a spaced-apart periphery. The optical zone has a first corrective power range in a first region and a second corrective power range in an annular region surrounding the first optical zone. The second corrective power is corrective of spherical aberration of an eye. The optical zone has a power profile that gradually changes from the first corrective power to the second corrective power. A central progressive zone that provides intermediate vision correction may be applied to a central region of the lens. The progressive zone has a diameter that is less than or equal to the diameter of an aperture of a pupil when subjected to bright light. SUMMARY The invention relates to an intraocular lens as defined in claim 1. Intraocular lenses for reducing ND are described herein. An example ophthalmic lens may include an optic including an anterior surface defining an anterior side of the optic, and a posterior surface defining a posterior side of the optic, wherein the posterior surface opposes the anterior surface. The lens includes a central optical zone disposed about the optical axis and an attenuation optical zone disposed about the central optical zone, wherein the attenuation optical zone is contiguous with the central optical zone, and wherein optical power of the ophthalmic lens is gradually reduced within the attenuation optical zone. Additionally, the optical power of the ophthalmic lens is gradually reduced to zero at an outermost edge of the attenuation optical zone. The outermost edge of the attenuation optical zone may be configured to minimize ray deviation as compared to a ray that misses the optic. In addition, a transition between the central optical zone and the attenuation optical zone may be smooth and continuous. A slope of the optic may be the same at a beginning of the attenuation optical zone and an end of the central optical zone. The attenuation optical zone may be configured to eliminate discontinui