EP-4678664-A3 - ANTI-HUMAN TRANSFERRIN RECEPTOR ANTIBODY PERMEATING BLOOD-BRAIN BARRIER
EP4678664A3EP 4678664 A3EP4678664 A3EP 4678664A3EP-4678664-A3
Abstract
Disclosed are a means to convert compounds having physiological or pharmacological activity and unable to pass through the blood-brain barrier into a form that allows them to pass through the blood-brain barrier, and compounds converted thereby. The means is an anti-human transferrin receptor antibody and the converted compounds are molecular conjugates between physiologically active protein or pharmacologically active low-molecular-weight compounds and an anti-human transferrin receptor antibody.
Inventors
- SONODA, HIROYUKI
- TAKAHASHI, KENICHI
Assignees
- JCR Pharmaceuticals Co., Ltd.
Dates
- Publication Date
- 20260506
- Application Date
- 20160624