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EP-4681733-A3 - ANTI-CERAMIDE ANTIBODIES

EP4681733A3EP 4681733 A3EP4681733 A3EP 4681733A3EP-4681733-A3

Abstract

Monoclonal antibodies directed to ceramide that inhibit apoptosis are disclosed. Humanized and scFv versions of the antibodies are also disclosed. Methods for prevention or treatment of apoptosis in a subject by administration of the anti-ceramide antibodies are disclosed.

Inventors

  • ROTOLO, JIMMY
  • KOLESNICK, RICHARD

Assignees

  • Memorial Sloan-Kettering Cancer Center
  • Ceramide Therapeutics

Dates

Publication Date
20260506
Application Date
20150807