EP-4707292-A3 - POLYPLOID ADENO-ASSOCIATED VIRUS VECTORS AND METHODS OF MAKING AND USING THE SAME
EP4707292A3EP 4707292 A3EP4707292 A3EP 4707292A3EP-4707292-A3
Abstract
The present invention provides a polyploid adeno-associated virus (AAV) capsid, wherein the capsid comprises capsid protein VP1, wherein said capsid protein VP1 is from one or more than one first AAV serotype, wherein said capsid protein VP2 is from one or more than one first AAV serotype and capsid protein VP3, wherein said capsid protein VP3 is from one or more than one second AAV serotype and wherein at least one of said first AAV serotype is different from at least one of said second AAV serotype and is different from at least one of said third AAV serotype, in any combination.
Inventors
- SAMULSKI, RICHARD, JUDE
- LI, CHENGWEN
Assignees
- The University of North Carolina at Chapel Hill
Dates
- Publication Date
- 20260506
- Application Date
- 20180315