EP-4707399-A3 - PEPTIDE-MODIFIED AAV CAPSID WITH ENHANCED MUSCLE TRANSDUCTION EFFICIENCY
EP4707399A3EP 4707399 A3EP4707399 A3EP 4707399A3EP-4707399-A3
Abstract
The invention relates to a peptide-modified AAV capsid having an increased muscle transduction efficiency. The invention relates also to the derived recombinant AAV vector particle packaging a gene of interest, and its use in gene therapy, in particular for treating muscle diseases.
Inventors
- RICHARD, ISABELLE
- HONG, Ai Vu
Assignees
- Généthon
- Institut National de la Santé et de la Recherche Médicale
- Université d'Evry Val d'Essonne
Dates
- Publication Date
- 20260506
- Application Date
- 20230609