A DEVICE FOR PREPARING A DNA PRODUCT BY MEANS OF CAPILLARY POLYMERASE CHAIN REACTION

Abstract

The present invention relates to a device for preparing a DNA product by means of Capillary Polymerase Chain Reaction (PCR); a manufacturing device for a pharmaceutical product; a manufacturing module for a pharmaceutical product; a method for preparing a DNA product by means of Capillary Polymerase Chain Reaction; the use of the device for preparing a DNA product by means of Polymerase Chain Reaction; and the use of the device for a production of a pharmaceutical product. The device for preparing a DNA product by means of Capillary Polymerase Chain Reaction comprises a tube for guiding a PCR liquid, a first compartment, and at least second compartment. The tube is wound at least from the first compartment to the second compartment and from the second compartment to the first compartment, wherein the tube wound from compartment to compartment forms a helical stack of tube windings. The first compartment and the second compartment each comprises means to adjust the temperature in the compartment to prepare the DNA product based on the PCR liquid, wherein the first compartment is configured to provide a temperature for denaturation and the second compartment is configured to provide a temperature for annealing and/or elongation.

Inventors

YAZDAN PANAH, Benyamin
Hoffmann, Philipp
WAGNER, Veronika
ROOS, TILMANN
BUOB, Dominik
GRACA, Telmo
THOMMEN, Michael
BERTSCH, Felix
KOHLEN, BERNHARD
RAUEN, Michael
SCHOLTES, Nico

Assignees

CureVac Manufacturing GmbH
Tesla Automation GmbH

Dates

Publication Date: 20260513
Application Date: 20211126