EP-4734876-A1 - SYSTEM AND METHODS FOR COMPENSATING FOR INTRAOCULAR LENS TILT

Abstract

Disclosed herein are systems and methods for compensating for a tilt of an intraocular lens (IOL) and systems and methods for adjusting the IOL. For example, one of the methods can comprise capturing one or more optical coherence tomography (OCT) images of an eye of a subject when the IOL is implanted within the eye of the subject. The method can also comprise generating a fixation target such that the fixation target is visible to the eye of the subject and moving the fixation target until a transverse plane of the IOL is perpendicular or substantially perpendicular to an optical axis of an ophthalmic system. The method can also comprise directing a laser beam generated by a laser of the ophthalmic system at the IOL.

Inventors

• BOR, ZSOLT

Assignees

• Alcon Inc.

Dates

Publication Date

20260506

Application Date

20240612

Claims (20)

1. 1. An ophthalmic system, comprising: an optical coherence tomography (OCT) imaging apparatus configured to produce one or more OCT images of an eye of a subject having an intraocular lens (IOL) implanted within the eye; and a fixation target source configured to generate a moveable fixation target that is visible to the eye of the subject, wherein the fixation target is configured to be moved until a transverse plane of the IOL is perpendicular or substantially perpendicular to an optical axis of the ophthalmic system.
2. 2. The ophthalmic system of claim 1, wherein the OCT imaging apparatus is communicatively coupled to an electronic display, and wherein moving the fixation target further comprises moving the fixation target until the transverse plane of the IOL as shown in the one or more OCT images displayed on the electronic display is perpendicular or substantially perpendicular to the optical axis displayed on the electronic display.
3. 3. The ophthalmic system of claim 1, further comprising a laser configured to generate and direct a laser beam at the IOL to adjust a base power of the IOL.
4. 4. The ophthalmic system of claim 3, wherein the optical axis of the ophthalmic system is a Z-axis of a focusing lens or focusing objective of the laser of the ophthalmic system and wherein the fixation target is configured to be moved to a position not axially aligned with the Z-axis.
5. 5. The ophthalmic system of claim 4, wherein the optical axis is oriented vertically when the subject is lying in a supine position.
6. 6. The ophthalmic system of claim 3, wherein the laser beam is generated by a femtosecond laser.
7. 7. The ophthalmic system of claim 1, wherein the ophthalmic system further comprises a control unit comprising one or more processors coupled to a memory, wherein the one or more processors are programmed to execute instructions stored on the memory to determine a degree of tilt of the IOL, and wherein the fixation target is configured to be moved based on the degree of tilt.
8. 8. The ophthalmic system of claim 7, wherein the degree of tilt of the IOL is between about 4.0 degrees and about 8.0 degrees.
9. 9. The ophthalmic system of claim 1, wherein the fixation target is moveable in at least one of a medial direction, a lateral direction, an inferior direction, and a superior direction with respect to the subject.
10. 10. The ophthalmic system of claim 1, wherein the fixation target is a fixation light generated by a fixation light source serving as the fixation target source.
11. 11. The ophthalmic system of claim 10, wherein the fixation light is a beam of light having a wavelength in a visible spectrum.
12. 12. The ophthalmic system of claim 1, wherein the fixation target is moveable in response to a user input by a user of the ophthalmic system.
13. 13. The ophthalmic system of claim 1, wherein the fixation target is configured to be automatically moved by the ophthalmic system.
14. 14. The ophthalmic system of claim 1, wherein the fixation target source is a target display visible to the subject.
15. 15. The ophthalmic system of claim 14, wherein the fixation target is a computergenerated graphic.
16. 16. The ophthalmic system of claim 1, wherein the OCT imaging apparatus is an integrated component of the ophthalmic system.
17. 17. The ophthalmic system of claim 1, wherein the IOL is an accommodating IOL.
18. 18. The ophthalmic system of claim 1, wherein the IOL is a non-accommodating fluid- adjustable IOL.
19. 19. A method of compensating for a tilt of an intraocular lens (IOL) with optical coherence tomography (OCT) guidance, comprising: capturing one or more OCT images of an eye of a subject using an OCT imaging apparatus, wherein the IOL is implanted within the eye of the subject; generating a fixation target such that the fixation target is visible to the eye of the subject; and moving the fixation target until a transverse plane of the IOL is perpendicular or substantially perpendicular to an optical axis of an ophthalmic system.
20. 20. A method of adjusting an intraocular lens (IOL), comprising: capturing one or more OCT images of an eye of a subject using an OCT imaging apparatus, wherein the IOL is implanted within the eye of the subject; generating a fixation target such that the fixation target is visible to the eye of the subject; moving the fixation target until a transverse plane of the IOL is perpendicular or substantially perpendicular to an optical axis of an ophthalmic system; and directing a laser beam generated by a laser of the ophthalmic system at the IOL to adjust a base power of the IOL.

Description

TITLE SYSTEM AND METHODS FOR COMPENSATING FOR INTRAOCULAR LENS TILT CROSS-REFERENCE TO RELATED APPLICATION [0001] This application claims priority to U.S. Patent Application No. 63/511,306 filed on June 30, 2023, the content of which is incorporated herein by reference in its entirety. TECHNICAL FIELD [0002] The present disclosure relates generally to the field of intraocular lenses, and, more specifically, to systems and methods for compensating for intraocular lens (IOL) tilt as part of an IOL adjustment procedure. BACKGROUND [0003] A cataract is a condition involving the clouding over of the normally clear lens of a subject’s eye. Cataracts occur as a result of aging, hereditary factors, trauma, inflammation, metabolic disorders, or exposure to radiation. Age-related cataract is the most common type of cataracts. In treating a cataract, the surgeon removes the native crystalline lens matrix from the subject’s capsular bag and replaces it with an intraocular lens (IOL). Traditional IOLS provide one or more selected focal lengths that allow the subject to have distance vision. However, after cataract surgery, subjects with traditional IOLs often require glasses or other corrective eyewear for certain activities since the eye can no longer undertake accommodation (or change its optical power) to maintain a clear image of an object or focus on an object as its distance varies. [0004] Newer IOLs such as accommodating IOLs, allow the eye to regain at least some focusing ability. Accommodating IOLs (AIOLs) use forces available in the eye to change some portion of the optical system in order to refocus the eye on distant or near targets. In addition, there may be a need to adjust AIOLs and non-accommodating IOLs post- operatively or after implantation within the eye of a subject. In some instances, an implanted IOL or AIOL may be adjusted using laser treatments. [0005] However, IOLs or AIOLs may be positioned or oriented in a manner within the eye that makes post-implant adjustment difficult. Therefore, improved solutions which allow a clinician or other medical professional to safely and accurately adjust an AIOL or IOL post-operatively may be beneficial. Such a solution should also be designed with clinical considerations in mind. SUMMARY [0006] Disclosed herein are systems and methods for compensating for a tilt of an intraocular lens (IOL) and systems and methods for adjusting the IOL. In some embodiments, a method of compensating for a tilt of an intraocular lens (IOL) with optical coherence tomography (OCT) guidance comprises: capturing one or more OCT images of an eye of a subject using an OCT imaging apparatus, wherein the IOL can be implanted within the eye of the subject; generating a fixation target such that the fixation target is visible to the eye of the subject; and moving the fixation target until a transverse plane of the IOL is perpendicular or substantially perpendicular to an optical axis of an ophthalmic system. [0007] In some embodiments, the OCT imaging apparatus can be communicatively coupled to an electronic display and wherein moving the fixation target further comprises moving the fixation target until the transverse plane of the IOL as shown in the one or more OCT images displayed on the electronic display is perpendicular or substantially perpendicular to the optical axis displayed on the electronic display. [0008] In some embodiments, the method can further comprise determining a degree of the tilt of the IOL and moving the fixation target based on the degree of tilt. [0009] In some embodiments, the tilt of the IOL can have a tilt angle between about 4.0 degrees and about 8.0 degrees. [0010] In some embodiments, moving the fixation target can further comprise moving the fixation target in at least one of a medial direction, a lateral direction, an inferior direction, and a superior direction with respect to the subject. [0011] In some embodiments, the optical axis of the ophthalmic system can be a Z-axis of a focusing lens or focusing objective of a laser of the ophthalmic system, and wherein moving the fixation target can further comprise moving the fixation target to a position not axially aligned with the Z-axis. [0012] In some embodiments, the optical axis can be oriented vertically when the subject is lying in a supine position. [0013] In some embodiments, the fixation target can be a fixation light generated by a fixation light source. [0014] In some embodiments, the fixation light can be a beam of light having a wavelength in a visible spectrum. [0015] In some embodiments, the fixation light can be moveable in response to a user input by a user of the ophthalmic system. [0016] In some embodiments, the fixation light source can be configured to be automatically moved by the ophthalmic system. [0017] In some embodiments, the fixation target can be displayed on a target display visible to the subject. [0018] In some embodiments, he fixation target can be a computer-generated