EP-4734939-A2 - ORAL CARE COMPOSITIONS COMPRISING HOPS BETA ACIDS

Abstract

An oral care composition includes hops and one or more surfactants. A solution including the hops and the one or more surfactants is clear or slightly hazy in a pH range of about 4.5 to about 9. If the one or more surfactants include sodium cocoyl glutamate, lauryl glucoside, or poloxamer, then the oral care composition includes at least two surfactants.

Inventors

• ST. JOHN, SAMUEL, JAMES
• BAIG, ARIF, ALI
• STRAND, ROSS

Assignees

• The Procter & Gamble Company

Dates

Publication Date

20260506

Application Date

20240627

Claims (20)

1. CLAIMS What is claimed is: 1. An oral care composition comprising: hops acid; and one or more surfactants, wherein a solution comprising the hops acid and the one or more surfactants has an initial optical density of 0.136 or less, preferably 0.100 or less, more preferably 0.072 or less, at 600 nm in a pH range of about 4.5 to about 9.
2. 2. The oral care composition of claim 1, wherein the one or more surfactants comprise sodium cocoyl glutamate, lauryl glucoside, or poloxamer, and the oral care composition comprises at least two surfactants.
3. 3. The oral care composition of claim 1, wherein the one or more surfactants consists of a single surfactant, and the single surfactant comprises less than about 2% of sodium methyl cocoyl taurate.
4. 4. The oral care composition of claim 1, wherein the one or more surfactants consists of a single surfactant, and the single surfactant does not comprise sodium cocoyl glutamate, lauryl glucoside, or poloxamer.
5. 5. The oral care composition of any one of claims 1 to 3, wherein the one or more surfactants are selected from the group consisting of sodium lauryl sulfate, cocamidopropyl betaine, sodium cocoyl glutamate, sodium methyl cocoyl taurate, or a combination thereof, preferably wherein the one or more surfactants consist essentially of sodium lauryl sulfate, cocamidopropyl betaine, sodium methyl cocoyl taurate, or a combination thereof.
6. 6. The oral care composition of any one of the preceding claims, wherein the oral care composition comprises from greater than 0% to about 5%, preferably greater than 0% to about 2%, by weight of the oral care composition, of the sodium lauryl sulfate, and the pH range is about 7 to about 9.
7. 7. The oral care composition of any one of the preceding claims, wherein the oral care composition comprises about 2%, by weight of the oral care composition, of the sodium lauryl sulfate, and the pH range is about 7 to about 9.
8. 8. The oral care composition of any one of the preceding claims, wherein the oral care composition comprises from greater than 0% to about 1%, by weight of the oral care composition, of the cocamidopropyl betaine, and the pH range is about 5 to about 9.
9. 9. The oral care composition of any one of claims 1-12, wherein the one or more surfactants comprises sodium lauryl sulfate as a main surfactant and a co-surfactant comprising cocamidopropyl betaine, sodium methyl cocoyl taurate, lauryl glucoside, or poloxamer.
10. 10. The oral care composition of any one of claims 1-12, wherein the one or more surfactants comprises cocamidopropyl betaine as a main surfactant and a co-surfactant comprising sodium lauryl sulfate, sodium methyl cocoyl taurate, lauryl glucoside, or poloxamer.
11. 11. The oral care composition of any one of claims 1-12, wherein the one or more surfactants comprises sodium methyl cocoyl taurate as a main surfactant and a co-surfactant comprising sodium lauryl sulfate, cocamidopropyl betaine, or lauryl glucoside.
12. 12. The oral care composition of any one of claims 1-12, wherein the one or more surfactants comprises lauryl glucoside as a main surfactant and a co-surfactant comprising sodium lauryl sulfate, preferably wherein the pH is from about 8 to about 9.
13. 13. The oral care composition of any one of claims 1-12, wherein the one or more surfactants comprises poloxamer as a main surfactant and a co-surfactant comprising sodium lauryl sulfate, cocamidopropyl betaine, sodium cocoyl glutamate, sodium methyl cocoyl taurate, or lauryl glucoside.
14. 14. The oral care composition of the preceding claim, wherein the co-surfactant comprises lauryl glucoside, preferably wherein the pH is from about 8 to about 9.
15. 15. The oral care composition of any one of the preceding claims, further comprising from about 0.01% to about 10%, by weight of the composition, of a metal ion source, preferably wherein the metal ion source comprises tin, zinc, or combinations thereof.
16. 16. The oral care composition of any one of the preceding claims, wherein the hops beta acid comprises only non-hydrogenated hops beta acid.
17. 17. The oral care composition of any one of the preceding claims, wherein the oral care composition comprises from greater than 0% to about 5%, preferably greater than 0% to about 3%, more preferably greater than 0% to about 2%, by weight of the composition, of the one or more surfactants.
18. 18. The oral care composition of claim 1, wherein the composition is a mouth rinse.
19. 19. An oral care composition comprising: hops acid; flavor; and one or more surfactants, wherein the oral care composition has an added salt concentration of at least 2.5%, by weight of the oral care composition, and a pH of about 5 to about 7.5, and wherein the oral care composition has phase stability.
20. 20. The oral care composition of claim 19, wherein the one or more surfactants comprises sodium lauryl sulfate.

Description

ORAL CARE COMPOSITIONS COMPRISING HOPS BETA ACIDS TECHNICAL FIELD The disclosure relates generally to oral care compositions and, more particularly, relates to oral care compositions comprising hops and surfactant with improved hops solubility. BACKGROUND Oral care compositions, such as toothpaste and/or dentifrice compositions, can be applied to the oral cavity to clean and/or maintain the aesthetics and/or health of the teeth, gums, and/or tongue. Additionally, many oral care compositions are used to deliver active ingredients directly to oral care surfaces. Natural compounds with antibacterial activity, such as hops, can be incorporated into oral care compositions to provide antibacterial and/or anticavity activity. Natural antibacterial agents, such as hops, can include mixtures of active compounds, oils, flavonoids, and/or other flavor compounds. Incorporating natural compounds into oral care compositions may affect the shelf-stability of the compositions. There is a need for oral care compositions with improved shelf-stability. SUMMARY An oral care composition is provided that includes hops and one or more surfactants, where a solution including the hops and the one or more surfactants is clear or slightly hazy in a pH range of about 4.5 to about 9. An oral care composition is provided that includes hops and one or more surfactants, where if the one or more surfactants comprise sodium cocoyl glutamate, lauryl glucoside, or poloxamer, then the oral care composition comprises at least two surfactants. A solution including the hops and the one or more surfactants is clear or slightly hazy in a pH range of about 4.5 to about 9. An oral care composition is provided that includes hops and one or more surfactants including sodium methyl cocoyl taurate, where a solution comprising the hops and the one or more surfactants is clear or slightly hazy in a pH range of about 4.5 to about 9. DETAILED DESCRIPTION Many natural antibacterial agents, including hops, have poor aqueous solubility and can phase separate from the toothpaste, collecting in the tip or partitioning along the composition/package interface. This results in a non-uniform distribution of the natural antibacterial agent such that the consumer cannot be guaranteed that they are receiving the proper amount of the agent during use. Embodiments of the present invention are directed to oral care compositions comprising one or more surfactants with hops beta acids, e.g., lupulone-sodium lauryl sulfate, adlupulone-cocamidopropyl betaine, or colupulone-sodium methyl cocoyl taurate, and/or others, that have improved hops stability. Solutions where hops beta acids are properly solubilized will improve the physical stability of the oral care composition and help prevent its phase separation in an aqueous composition. While not wishing to being bound by theory, it is believed that the combination of one or more surfactants with a hops beta acid extract can lead to increased phase stability of oral care compositions comprising a hops beta acid extract. The stability in a dentifrice composition may be assessed based on a liquid composition without colloidal stabilizers like abrasive and polymer binders. Such a composition may be considered sufficiently stable that there would not be bulk phase separation in the presence of colloidal stabilizers like abrasive and polymer binders where there is no visible separation, where discontinuous droplets are present, or a combination thereof. A composition that separates into continuous layers would be considered to lack phase stability. Definitions To define more clearly the terms used herein, the following definitions are provided. Unless otherwise indicated, the following definitions are applicable to this disclosure. If a term is used in this disclosure but is not specifically defined herein, the definition from the IUPAC Compendium of Chemical Terminology, 2nd Ed (1997), can be applied, as long as that definition does not conflict with any other disclosure or definition applied herein, or render indefinite or non-enabled any claim to which that definition is applied. The term "oral care composition", as used herein, includes a product, which in the ordinary course of usage, is not intentionally swallowed for purposes of systemic administration of particular therapeutic agents, but is rather retained in the oral cavity for a time sufficient to contact dental surfaces or oral tissues. Examples of oral care compositions include dentifrice, toothpaste, tooth gel, subgingival gel, emulsion, mouth rinse, mousse, foam, mouth spray, lozenge, chewable tablet, chewing gum, tooth whitening strips, floss and floss coatings, breath freshening dissolvable strips, unit-dose composition, fibrous composition, or denture care or adhesive product. The oral care composition may also be incorporated onto strips or films for direct application or attachment to oral surfaces, such as tooth whitening strips. Examples of emulsion compositio