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EP-4739278-A1 - ANIMAL TREAT FOR ANIMAL ORAL HYGIENE

EP4739278A1EP 4739278 A1EP4739278 A1EP 4739278A1EP-4739278-A1

Abstract

The present document describes an edible composition for oral hygiene of an animal which comprises a dental abrasive comprising treated aragonite calcium carbonate (CaCO 3 ) particles having more than 95% (w/w) calcium carbonate content, a specific surface area (SSA) of about 2.70 to about 3.1 m2/g, the treated aragonite calcium carbonate particles having been effectively treated in mildly acidic condition, a pregelatinized starch; a plasticizer; and a binder. Also described are methods of cleaning an oral cavity of an animal with the edible compositions, as well as methods for preparing the edible composition of the present invention.

Inventors

  • ROSSI, JOANNA
  • MCDONNELL, KEVIN

Assignees

  • Dentalis Animal Health Inc.

Dates

Publication Date
20260513
Application Date
20240704

Claims (20)

  1. 1 . An edible composition for oral hygiene of an animal comprising: a) from about 1% to about 20% w/w of a dental abrasive comprising • treated aragonite calcium carbonate (CaCOa) particles having more than 95% (w/w) calcium carbonate content, a specific surface area (SSA) of about 2.70 to about 3.1 m 2 /g, said treated aragonite calcium carbonate particles having been effectively treated in mildly acidic condition; b) from about 15% to about 40% w/w of a pregelatinized starch; c) from about 11% to about 45% w/w of a plasticizer; and d) from about 0.5% to about 5% w/w of a binder.
  2. 2. The edible composition of claim 1 , wherein said treated aragonite calcium carbonate particles have a particle size of from about 25 microns to about 70 microns.
  3. 3. The edible composition of claim 1 , wherein said calcium carbonate content is from about 95% to about 99.9% (w/w).
  4. 4. The edible composition of claim 1 , wherein said particles have a specific surface area of from about 2.80 m 2 /g to about 2.9 m 2 /g.
  5. 5. The edible care composition of claim 1 , wherein said particles have a specific surface area of from about 2.9 m 2 /g.
  6. 6. The edible composition of any one of claims 1 - 5, wherein said treated aragonite calcium carbonate (CaCOa) particles are from an aragonite of vegetal origin.
  7. 7. The edible composition of claim 6, wherein said aragonite of vegetal origin is oolitic aragonite.
  8. 8. The edible composition of any one of claims 1 - 7, wherein said treated aragonite calcium carbonate (CaCOa) particles have a crystallinity of about 24% to about 28%.
  9. 9. The edible of any one of claims 1 - 7, wherein said treated aragonite calcium carbonate (CaCOa) particles have a crystallinity of about 26%.
  10. 10. The edible composition of any one of claims 1 to 9, wherein said plasticizer comprises water, glycerin, a polyethylene glycol (PEG), polyethylene glycol monomethyl ether, propylene glycol, triacetin, tributyl citrate, triethyl citrate, acetyl tributyl citrate, acetyl triethyl citrate, diethyl phthalate, acetic acid, formic acid, 1 -butanol, 2-butanol, ethanol, 2-methyl-1 -butanol, 2-methyl-1 -propanol, 1- pentanol, 1 -propanol, 2-propanol, ethyl acetate, ethyl formate, isopropyl acetate, methyl acetate, propyl acetate, anisole, tert-butylmethyl ether, ethyl ether, cumene, heptane, pentane, acetone, methylethyl ketone, methylisobutyl ketone, dimethyl sulfoxide, castor oil, propylene glycol, diacetylated monoglycerides, sorbitol, sorbitan, dibutyl sebacate, or combinations thereof.
  11. 11. The edible composition of claim 10, wherein said plasticizer is water, glycerin, ora combination thereof.
  12. 12. The edible composition of any one of claims 1 to 10, wherein said binder comprises a cellulose, a gelatin, a polyvinyl pyrrolidone, a starch, sucrose, mannitol, a polyethylene glycol, liquid glucose, polyvinyl pyrrolidone (PVP), hydroxy propyl methyl cellulose (HPMC), sodium carboxymethyl cellulose, methyl cellulose, acacia gum, xanthan gum, locust bean gum, a chitosan, a dextran, guar gum, inulin, a dextrin, a maltodextrin, polyethylene oxide, sodium alginate, zein, carrageenan or combinations thereof.
  13. 13. The edible composition of claim 12, wherein said binder is xanthan gum.
  14. 14. The edible composition of any one of claims 1 to 13, wherein said pregelatinized starch is a partially pregelatinized starch, a fully pregelatinized starch, or a combination thereof.
  15. 15. The edible composition of claim 14, wherein said pregelatinized starch is a fully pregelatinized starch.
  16. 16. The edible composition of any one of claims 14 - 15, wherein said pregelatinized starch is from a potato starch, a corn starch, a rice starch, a wheat starch, a cassava starch, or combinations thereof.
  17. 17. The edible composition of any one of claims 1 to 16, further comprising a lubricant.
  18. 18. The edible composition of claim 17, wherein said lubricant is from about 1 % to about 15% w/w of the composition.
  19. 19. The edible composition of any one of claims 17 - 18, wherein said lubricant is magnesium stearate, calcium stearate, stearic acid, purified talc, a light PEG, sodium stearyl fumerate, sodium lauryl sulphate, a long chain triglyceride (LCT), a medium chain triglyceride (MCT), a short chain triglyceride (SCT) or combinations thereof.
  20. 20. The edible composition of claim 19, wherein said lubricant is magnesium stearate, said medium chain triglyceride, or a combination thereof.

Description

ANIMAL TREAT FOR ANIMAL ORAL HYGIENE CROSS-REFERENCE TO RELATED APPLICATIONS [0001] This application claims priority of US provisional patent application No. 63/525,171 filed July 6, 2023 , the specification of which is hereby incorporated by reference in its entirety. BACKGROUND (a) Field [0002] The subject matter disclosed generally relates to an edible composition for oral hygiene of an animal, and methods of making the same. More specifically, the subject matter disclosed relates to an edible composition for oral hygiene of an animal comprising treated aragonite particles. (b) Related Prior Art [0003] Animals, such as dogs and cats, are susceptible to a variety of dental health issues such as bad breath, gum irritation, plaque and tartar formation and stained teeth. Plaque is characterized as a biofilm consisting of bacteria and other components that tightly adheres to the teeth and is not easily washed away once formed. Tartar (or dental calculus) develops from the thickening and hardening (mineralization) of the plaque. Tartar buildup on the teeth can cause irritation of the gums and can lead to gingivitis. Removal of tartar is very difficult and is typically done by mechanical means such as physically scraping off the formed tartar with an abrasive. [0004] A wide variety of commercial products are available to address a pet’s dental and oral health. A number of these products are pieces of rawhide in various forms and shapes or pieces of rope knotted on its ends to resemble bones. Other examples of products designed to treat a pet’s dental and oral health are edible treats, which can be given to the animal on a daily basis. These products are typically hard in texture and come in various sizes, shapes and designs, such as a toothbrush or a dog bone. It is generally desired for the animal to chew on the dental product for as long as possible (ideally several minutes). The longer the chew time, the better the expected teeth cleaning because of the mechanical action of the product scraping the tartar and plaque off the teeth. Furthermore, animal food products for a pet’s dental and oral health commonly help reduce plaque and tartar formation in part through the shape of the product, which comprise ridges, sharp edges, and other three-dimensional features, as well as the hardness of the products, which causes physical and mechanical action on the teeth of the animal chewing the product. [0005] The present description assesses the efficacy of an edible composition for oral hygiene of an animal containing a specific preparation of treated aragonite calcium carbonate (CaCOs) as abrasive. SUMMARY [0006] According to an embodiment, there is provided an edible composition for oral hygiene of an animal comprising: a) from about 1% to about 20% w/w of a dental abrasive comprising • treated aragonite calcium carbonate (CaCOa) particles having more than 95% (w/w) calcium carbonate content, a specific surface area (SSA) of about 2.70 to about 3.1 m2/g, the treated aragonite calcium carbonate particles having been effectively treated in mildly acidic condition; b) from about 15% to about 40% w/w of a pregelatinized starch; c) from about 11% to about 45% w/w of a plasticizer; and d) from about 0.5% to about 5% w/w of a binder. [0007] The treated aragonite calcium carbonate particles may have a particle size of from about 25 microns to about 70 microns. [0008] The calcium carbonate content may be from about 95% to about 99.9% (w/w). [0009] The particles may have a specific surface area of from about 2.80 m2/g to about 2.9 m2/g. [0010] The particles may have a specific surface area of from about 2.9 m2/g. [0011] The treated aragonite calcium carbonate (CaCOa) particles may be from an aragonite of vegetal origin. [0012] The aragonite of vegetal origin may be oolitic aragonite. [0013] The treated aragonite calcium carbonate (CaCOa) particles may have a crystallinity of about 24% to about 28%. [0014] The treated aragonite calcium carbonate (CaCOa) particles may have a crystallinity of about 26%. [0015] The plasticizer may comprise water, glycerin, a polyethylene glycol (PEG), polyethylene glycol monomethyl ether, propylene glycol, triacetin, tributyl citrate, triethyl citrate, acetyl tributyl citrate, acetyl triethyl citrate, diethyl phthalate, acetic acid, formic acid, 1 -butanol, 2-butanol, ethanol, 2-methyl-1 -butanol, 2-methyl-1 -propanol, 1-pentanol, 1 -propanol, 2-propanol, ethyl acetate, ethyl formate, isopropyl acetate, methyl acetate, propyl acetate, anisole, tert-butylmethyl ether, ethyl ether, cumene, heptane, pentane, acetone, methylethyl ketone, methylisobutyl ketone, dimethyl sulfoxide, castoroil, propylene glycol, diacetylated monoglycerides, sorbitol, sorbitan, dibutyl sebacate, or combinations thereof. [0016] The plasticizer may be water, glycerin, or a combination thereof. [0017] The binder may comprise a cellulose, a gelatin, a polyvinyl pyrrolidone, a starch, sucrose, mannitol, a polyethylene glyco