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EP-4739280-A1 - PREPARATION DEVICE FOR THE USE OF A LIVE ACTIVATED PROBIOTIC PREPARATION

EP4739280A1EP 4739280 A1EP4739280 A1EP 4739280A1EP-4739280-A1

Abstract

A device (1) is provided for preparing a preparation (2) comprising a powder (21) with probiotics and a diluent (22) of the powder (21); the device (1) includes a chamber (3a) containing powder (21) and diluent (22); and an activator configured to activate and thus make the probiotics immediately usable by maintaining the powder (21) at an activation temperature between 30°C and 40°C for an activation time between 20 minutes and 40 minutes.

Inventors

  • BRUNORI, Daniele

Assignees

  • Probelive S.r.l.

Dates

Publication Date
20260513
Application Date
20240703

Claims (15)

  1. 1. The device (1 ) for preparing a preparation (2) configured to make said preparation (2) ready to use; said preparation (2) being characterized by comprising: - powder (21 ) comprising added live quiescent probiotics; - sugars; and - a diluent (22) of suspension of said powder (21 ); and said device (1 ) being characterised by comprising - a chamber (3a) containing said powder (21 ) and said diluent (22); - an activator (4) configured to bring said powder (21 ) in said diluent (22) to an activation temperature substantially between 15°C and 45°C and to maintain said activation temperature for an activation time between 1 minute and 40 minutes so as to biologically activate said probiotics in said powder (21 ) and thereby render said live activated probiotics in said powder (21 ) immediately usable and takeable when suspended in said diluent (22).
  2. 2. The device (1 ) according to claim 1 , wherein said activation temperature is substantially between 30°C and 40°C.
  3. 3. The device (1 ) according to claim 2, wherein said activation temperature is substantially equal to 37°C ± 2°C and said activation time is substantially equal to 25 ± 5 minutes.
  4. 4. A device (1 ) according to at least one preceding claim, comprising an agitator (5) configured to mix said powder (21 ) with said diluent (22) in said chamber (4a) for a mixing time substantially between 10 minutes and 15 minutes.
  5. 5. A device (1 ) according to at least one preceding claim, wherein the concentration of said sugars in said preparation (2) is substantially between 0.01 g and 5 g per 100 mL of said preparation (2).
  6. 6. A device (1 ) according to at least one preceding claim, wherein said sugars is dissolved in said diluent.
  7. 7. The device (1 ) according to the preceding claim, wherein said preparation (2) is a cosmetic, nutraceutical, food, agricultural, veterinary, industrial, pharmaceutical preparation.
  8. 8. The device (1 ) according to the preceding claim, wherein said preparation (2) has a pH substantially equal to 7 ± 2.
  9. 9. The process (100) for preparing a preparation (2) configured to make said preparation (2) ready to use; said preparation (2) comprising: - powder (21 ) comprising probiotics; and - a diluent (22) of suspension of said powder (21 ); and said process (100) being characterised by comprising - a dispersion step (110) of said powder (21 ) in said diluent (22); - an activation step (120) in which said probiotics in said powder (21 ), suspended in said diluent (22), are activated and rendered immediately usable and then takeable by bringing said powder (21 ) to an activation temperature between 15°C and 45°C and maintaining said powder (21 ) and then said diluent (22) at said activation temperature for an activation time substantially between 1 minute and 40 minutes.
  10. 10. The process (100) according to the preceding claim, wherein said activation temperature is substantially equal to 37°C ± 2°C and said activation time is substantially equal to 25 ± 5 minutes.
  11. 11. A process (100) according to at least one claim 9-10, comprising a mixing step (130) wherein said powder (21 ) and said diluent (22) are agitated so as to promote the maintenance in suspension of said powder (21 ) in said diluent (22); wherein said mixing step (130) is performed for a mixing time substantially between 1 minute and 40 minutes; and wherein said mixing step (130) is subsequent to said dispersion step (110) and to said activation step (120).
  12. 12. The process (100) according to the preceding claim, wherein said mixing time is substantially equal to said activation time.
  13. 13. A process (100) according to at least one claim 11 -12, wherein said mixing time is substantially between 10 minutes and 15 minutes.
  14. 14. A process (100) according to at least one claim 11 -13, wherein said mixing step (130) is prior to said activation step (120).
  15. 15. A process (100) according to at least one claim 11 -13, wherein said mixing step (130) is performed in parallel with said activation step (120).

Description

DESCRI PTION PREPARATION DEVICE FOR THE USE OF A LIVE ACTIVATED PROBIOTIC PREPARATION The present invention relates to a preparation device for a probiotic preparation, specifically a preparation containing one or more probiotic strains, as specified in the preamble of the first claim. More specifically, the invention aims to create the conditions for biologically activating such freeze-dried live probiotics through a particular and innovative sequence of phases before their use. According to the official FAO and WHO definition, probiotics are live microorganisms that, when applied in adequate amounts, can provide multiple benefits to the body. A first example of the application of probiotic preparations, and thus of a probiotic preparation, is identified in supplements where beneficial effects have been observed on the digestive system, urogenital system, immune function and infection prevention, and in combating cholesterol and blood pressure. Another example of application is in the cosmetic field, where these microorganisms promote and support the strengthening of the skin barrier, restoration of the microbiome, maintenance of skin hydration, and regulation of sebum production. It is specified that the benefits previously described are not always the result of the combined action of multiple probiotic strains, but can also be due to a single probiotic strain. The known technique described includes some important drawbacks. A first problem is that live probiotics are ingested/used in their vital state but not efficiently activated at a metabolic level, resulting in a limited action of the probiotic itself, and thus a reduction in the beneficial effects. A second drawback is that probiotics remain viable (in solution or added to matrices such as yogurt, creams, lotions, masks, or muds) for a limited time period, thus necessitating their relatively rapid use/ingestion and reducing their storage time in the aforementioned conditions. In fact, these quiescent live organisms, when added to matrices for long periods, may suffer from interaction with the matrices themselves and consequently reduce their viability; or suffer from contamination due to environmental bacteria/fungi that thus alter the composition of the preparation. For these reasons, the use/ingestion, especially topical, of live and biologically activated probiotics is particularly laborious, complex, and not applicable. It is highlighted how these difficulties are greatly limiting the spread and use of probiotics, for example in the cosmetic field, despite their particularly high efficacy. In this situation, the technical task underlying the present invention is to devise a preparation device for the use of a live and biologically active probiotic preparation capable of substantially overcoming multiple of the aforementioned drawbacks. Within the scope of said technical task, the primary purpose of the invention is to obtain a device that allows simple and practical preparation, and therefore use, of a viable probiotic in its biologically activated state. One purpose is therefore to have a device that allows for the correct and completely safe preparation and subsequent use of a preparation containing live probiotics made biologically active even in the domestic environment, in order to optimize the benefits derived from the probiotic charge present in the final product. The technical task and the specified purposes are achieved by a preparation device as claimed in the annexed claim 1. Examples of preferred embodiments are described in the dependent claims. The characteristics and advantages of the invention are clarified below by the detailed description of preferred embodiments of the invention, with reference to the accompanying drawings, in which: Fig. 1 shows an example of a preparation device according to the invention; and Fig. 2 presents a schematic diagram of the functioning of the preparation device according to the invention. In this document, measurements, values, shapes, and geometric references (such as perpendicularity and parallelism), when associated with words like “approximately” or other similar terms such as “almost” or “substantially,” are to be understood as except for errors of measurement or imprecisions due to production and/or manufacturing errors and, above all, except for a slight departure from the value, measurement, shape, or geometric reference with which it is associated. For example, such terms, if associated with a value, preferably indicate a divergence of no more than 10% of the value itself. Furthermore, when terms like “first,” “second,” “upper,” “lower,” “main,” and “secondary” are used, they do not necessarily identify an order, a priority of relation or relative position, but can simply be used to more clearly distinguish different components from one another. Unless otherwise indicated, “perpendicular,” “transverse,” “parallel,” or “normal,” or other terms of geometric positioning between geometri