JP-2022535532-A5 -

Dates

Publication Date

20230522

Application Date

20200514

Description

Descriptions of elements in the figures should be understood to apply equally to corresponding elements in other figures unless otherwise indicated. While specific embodiments are illustrated and described herein, it will be understood by those skilled in the art that these specific embodiments may be replaced by various alternative and/or equivalent embodiments without departing from the scope of this disclosure. This application is intended to encompass any adaptation or modification of any specific embodiment discussed herein. Therefore, this disclosure is intended to be limited only by the claims and their equivalents. In addition to the embodiments described above, the following embodiments are also noted. (Note 1) A device for measuring peripheral nerve damage, Housing and An actuator accessible from the outer surface of the housing and configured to generate a stimulus signal to the skin surface of the subject, A processing circuit, The actuator is controlled to generate the aforementioned stimulus signal, and Record the response to the aforementioned stimulus signal. A processing circuit configured as follows, A device equipped with the following features. (Note 2) The apparatus according to Appendix 1, wherein the housing includes a section having a mechanically compatible surface that contacts the actuator. (Note 3) The apparatus described in Appendix 1, further comprising an accelerometer for measuring vibrations. (Note 4) The apparatus according to Appendix 3, further comprising a memory, wherein the processing circuit is further configured to record vibrations measured by the accelerometer, as well as any of the following in the memory: date information, time information, stimulus information, protocol information, subject identification information, and subject response information. (Note 5) The apparatus according to Appendix 1, wherein the stimulus signal includes a vibration signal, and the processing circuit is configured to record subject response information and stimulus information based on at least one of the amplitude or phase of the vibration signal. (Note 6) Housing and An actuator assembly accessible from the outer surface of the housing, An actuator configured to generate a stimulus signal to the skin surface of a subject, A processing circuit, The actuator is controlled to generate the aforementioned stimulus signal, and Record the response to the aforementioned stimulus signal. A processing circuit configured as follows, An actuator assembly including, A feedback device, Receive user input, and Providing feedback to clinician devices A feedback device configured as follows, It is a clinical device, A test input is provided to the processing circuit of the actuator assembly, and Receives a response from the aforementioned feedback device. A clinician device configured as follows, A system equipped with these features. (Note 7) The system according to Appendix 6, wherein the housing includes a section having a mechanically compatible surface that contacts the actuator. (Note 8) The system as described in Appendix 7, wherein the stimulus signal is mainly along an axis perpendicular to the mechanically compatible surface. (Note 9) The system according to Appendix 5, wherein the stimulus signal includes a vibration signal, and the processing circuit is configured to record subject response information and stimulus information based on at least one of the amplitude or phase of the vibration signal. (Note 10) The system according to Appendix 5, wherein the stimulus signal has a frequency, amplitude, or phase provided by the test protocol. (Note 11) A method for measuring peripheral neuropathy, To provide vibrational tactile stimulation to an actuator that is in physical contact with the subject's skin surface, Receiving a first instruction regarding whether the aforementioned vibration tactile stimulus has been detected, To provide a tremor detection assembly, Receiving a second instruction regarding the presence or absence of tremors, To diagnose neurological disorders, the first and second instructions are analyzed, Methods that include... (Note 12) The method according to Appendix 11, wherein the vibratory tactile stimulation includes a series of pulses based on a standard benchmark or protocol. (Note 13) The method according to Appendix 12, wherein at least one pulse in the series of pulses has a frequency of about 0.4 to 100 Hz to stimulate Merkel receptors, at least one pulse in the series of pulses has a frequency of about 7 Hz to stimulate Ruffini bodies, and at least one pulse in the series of pulses has a frequency of about 10 Hz to about 200 Hz to stimulate Meissner bodies. (Note 14) The method according to Appendix 13, wherein the series of pulses includes pulses from two or more frequency ranges. (Note 15) The vibration tactile stimulation is provided to a plurality of actuators that physically contact a plurality of points on the skin surface of the subject, Receiving ins