JP-2025515482-A5 -

Dates

Publication Date

20260508

Application Date

20230424

Description

While various illustrative embodiments of the present invention are described above, it will be apparent to those skilled in the art that various changes and modifications may be made therein without departing from the invention. For example, the pump assembly 70 shown in Figure 9 may be ordered differently and may include additional or fewer components of various sizes and compositions. The appended claims are intended to cover all such changes and modifications that fall within the true spirit and scope of the invention. This application provides the invention in the following embodiments. (Aspect 1) A housing having an inlet and outlet configured to communicate fluidly with the patient's circulatory system; A membrane disposed within the housing; An actuator disposed within the housing, configured to pump blood by causing the membrane to reciprocate; and An encapsulation assembly configured to encapsulate an actuator so that blood does not come into contact with the actuator, the encapsulation assembly being located within a housing and configured to define a flow path between the housing and the encapsulation assembly. A blood pump system comprising, A blood pump system in which, during operation, blood enters the inlet, flows between the housing and the encapsulation assembly within the flow path, is pushed across the membrane to the outlet, and pumps the blood. (Aspect 2) The blood pump system according to embodiment 1, wherein the actuator further comprises a magnetic assembly. (Aspect 3) The blood pump system according to embodiment 2, wherein the magnetic assembly is annular. (Aspect 4) A blood pump system according to embodiment 2, further comprising at least one spring coupled to the magnetic assembly, The encapsulated assembly is coupled to the magnetic assembly, and The blood pump system wherein at least one spring and the encapsulation assembly apply a spring force to the magnetic assembly. (Aspect 5) The blood pump system according to embodiment 1, wherein the encapsulation assembly reduces the risk of damage to the blood due to shear conditions. (Aspect 6) The blood pump system according to embodiment 1, wherein the flow path is configured to minimize damage to von Willebrand factor polymers in the blood. (Aspect 7) The blood pump system according to embodiment 1, wherein the flow path is fixed in size and configured to promote blood flow toward the outlet and resist blood flow toward the inlet. (Appendix 8) The blood pump system according to embodiment 1, wherein the flow path is fixed in size and configured to reduce the risk of shear conditions of the blood in the flow path and to reduce the recirculation of the blood. (Aspect 9) The blood pump system according to embodiment 1, further comprising an encapsulated fluid disposed between the encapsulation assembly and the actuator. (Aspect 10) The blood pump system according to embodiment 9, wherein the encapsulated fluid is a perfluorocarbon. (Phenomenon 11) The blood pump system according to embodiment 9, wherein the encapsulated fluid is selected from one of silicone oil, physiological saline, deionized water, or perfluorodecalin. (Aspect 12) A housing having an inlet and an outlet, wherein the outlet is designed to be in fluid communication with the patient's circulatory system; An actuator comprising an electromagnetic assembly configured to generate a magnetic field; the actuator assembly is located within the housing, Stator assembly coupled to the actuator; A magnetic assembly configured to reciprocate in response to the magnetic field; and An encapsulation assembly coupled to the magnetic assembly and the stator assembly, the encapsulation assembly being designed to encapsulate the actuator together with the magnetic assembly and the stator assembly; and A flexible film coupled to the magnetic assembly and configured to reciprocate in response to the magnetic assembly; A blood pump system comprising, The blood pump system, during operation, wherein blood enters the inlet, flows between the inner wall of the housing and the magnetic assembly, the stator assembly, and the encapsulation assembly, and is pushed across the flexible membrane to the outlet. (Aspect 13) The blood pump system according to embodiment 12, wherein the stator assembly comprises an upper stator assembly and a lower stator assembly. (Aspect 14) The blood pump system according to embodiment 13, wherein the upper stator assembly and the lower stator assembly are each coupled to the magnetic assembly. (Phenomenon 15) The blood pump system according to embodiment 13, wherein the magnetic assembly is annular. (Aspect 16) The blood pump system according to embodiment 13, further comprising at least one spring coupled to the magnetic assembly. (Aspect 17) The blood pump system according to embodiment 12, wherein the encapsulation assembly reduces the risk of damage to the blood due to shear conditions. (Phenomenon 18) The blood pump system according to embodiment 17, wh