JP-2025517917-A5 -

Dates

Publication Date

20260511

Application Date

20230512

Description

The foregoing specification is considered sufficient for those skilled in the art to carry out the present invention. The examples are intended merely as illustrations of one aspect of the present invention, and other functionally equivalent embodiments are within the scope of the present invention; therefore, the present invention is not limited by the provided examples. In addition to those shown and described herein, various modifications of the present invention will be apparent to those skilled in the art from the foregoing description and fall within the scope of the appended claims. The advantages and objectives of the present invention are not necessarily encompassed in each embodiment of the present invention. Finally, preferred embodiments of the present invention are described in separate sections. [Embodiment 1] A copolymer comprising a plurality of first repeating units, a plurality of second repeating units, and a plurality of third repeating units, The first repeating unit is zwitterionic; At least a portion of the second repeating unit each independently includes a crosslinkable portion; At least a portion of the third repeating unit is ionizable; The copolymer wherein the second repeating unit and the third repeating unit are different. [Embodiment 2] The copolymer according to Embodiment 1, wherein each of the first repeating units independently comprises a sulfobetaine group, a carboxybetaine group, a phosphorylcholine group, an imidazolium alkyl sulfonate group, a pyridinium alkyl sulfonate group, or a carboxybetaine group. [Embodiment 3] The copolymer according to Embodiment 1, wherein each of the zwitterionic repeating units is independently formed from sulfobetaine acrylate, sulfobetaine acrylamide, carboxybetaine acrylate, carboxybetaine methacrylate, 2-methacryloyloxyethyl phosphorylcholine, acrylooxyphosphorylcholine, phosphorylcholine acrylamide, phosphorylcholine methacrylamide, carboxybetaine acrylamide, carboxybetaine vinylpyridine, carboxybetaine vinylimidazole, 3-(2-vinylpyridinium-l-yl)propane-l-sulfonate, 3-(4-vinylpyridinium-l-yl)propane-l-sulfonate, sulfobetaine methacrylate, or a combination thereof. [Embodiment 4] The copolymer according to any one of embodiments 1 to 3, wherein at least a portion of the second repeating unit includes a hydrophobic repeating unit. [Embodiment 5] The copolymer according to any one of embodiments 1 to 3, wherein at least a portion of the second repeating unit includes a hydrophilic repeating unit. [Embodiment 6] The copolymer according to Embodiment 4, wherein the hydrophobic repeating units are independently formed from styrene, alkyl acrylate, alkyl methacrylate, alkyl acrylamide, acrylonitrile, aryl acrylate, aryl methacrylate, aryl acrylamide, allyl acrylate, allyl acrylamide, allyl methacrylamide, vinyl methacrylate, vinyl methacrylamide, vinyl acrylamide, allyl vinylbenzene (styrene derivative), cinnamate, benzophenone, isopropylthioxanthone, or a combination thereof. [Embodiment 7] The copolymer according to any one of embodiments 1 to 6, wherein the second portion of the second repeating unit comprises a second type of hydrophobic repeating unit. [Embodiment 8] The copolymer according to Embodiment 7, wherein each of the second type of hydrophobic repeating units is independently formed from alkyl acrylate, alkyl methacrylate, alkyl acrylamide, acrylonitrile, aryl acrylate, aryl methacrylate, aryl acrylamide, trifluoroethyl methacrylate, methyl methacrylate, ethyl methacrylate, n-propyl methacrylate, n-butyl methacrylate, acrylonitrile, styrene, or a combination thereof. [Embodiment 9] The copolymer according to any one of embodiments 1 to 8, wherein at least a portion of the second repeating unit does not contain a crosslinkable portion. [Embodiment 10] The copolymer according to Embodiment 9, wherein each second repeating unit, which does not contain a crosslinkable portion, is independently formed from acrylate, methacrylate, acrylamide, methacrylamide, trifluoroethyl methacrylate, methyl methacrylate, ethyl methacrylate, n-propyl methacrylate, n-butyl methacrylate, acrylonitrile, styrene, or a combination thereof. [Method 11] The crosslinkable portion comprises a carbon-carbon double bond, as described in any one of Embodiments 1 to 10. [Embodiment 12] The copolymer according to Embodiment 11, wherein the crosslinkable portion comprises allyl (CH₂ - CH=CH₂ ) , vinyl (-CH=CH₂ or -CH=CH-), vinyl ether (-O-CH= CH₂ ), or vinyl ester (-CO-O-CH=CH₂ ) . [Embodiment 13] The copolymer according to any one of embodiments 1 to 10, wherein the crosslinkable portion is polymerized (e.g., crosslinked) via exposure to one or more of the following: a free radical photoinitiator, electromagnetic radiation, high temperature, a redox reaction, or a combination thereof. [Embodiment 14] Each of the ionizable third repeating units is independently formed from a methacrylate, acrylate, acrylamide, or styrene derivative, or a combination thereof, as