JP-2026074535-A - Medical devices

Abstract

[Problem] To provide a medical device that can effectively dilate the urethra of a patient and further reduce the burden on the patient. [Solution] The medical device 100 includes one or more first magnets 110 that are implanted in the prostate gland P located around the urethra U to be dilated, and one or more second magnets 120 that can be placed outside the body O of the subject in which the first magnets are implanted, and generate a traction force that dilates the urethra in relation to the first magnets. [Selection Diagram] Figure 1

Inventors

• 津村 遼介
• 葭仲 潔

Assignees

• 国立研究開発法人産業技術総合研究所

Dates

Publication Date

20260507

Application Date

20241021

Claims (7)

1. A medical device used to dilate the urethra, One or more first magnets are implanted in the prostate gland, located around the urethra to be dilated, A medical device comprising one or more second magnets that can be positioned outside the body of a subject to be implanted with the first magnet, and that generate a traction force between themselves and the first magnet to expand the urethra.
2. The medical device according to claim 1, comprising two or more of the first magnets.
3. The medical device according to claim 2, wherein each of the two or more first magnets is arranged at a predetermined distance from each other at least in the transverse direction in the cross-section of the prostate.
4. Having three or more of the first magnets, A medical device according to claim 2 or 3, which generates the aforementioned traction force of 2 N or more.
5. The medical device according to claim 1, used in a patient suffering from benign prostatic hyperplasia, wherein the Young's modulus of the biological tissue at the implantation site of the first magnet is 30 kPa or more and 46 kPa or less.
6. The medical device according to claim 1, wherein the first magnet is a rod-shaped magnet having a longitudinal direction extending along the direction of implantation into the prostate.
7. The medical device according to claim 6, wherein the first magnet is a rod-shaped magnet having a magnetization direction in the short-side direction.

Description

This invention relates to a medical device used for urethral dilation. Benign prostatic hyperplasia (BPH) is a condition in which the prostate gland enlarges due to factors such as aging and hormonal imbalances. This enlargement compresses the urethra, causing urinary problems and various complications (e.g., urinary tract infections, bladder stones, kidney dysfunction, etc.). Traditionally, drug therapy and TUR-P (Transurethral resection of prostate) have been known as treatment methods for benign prostatic hyperplasia (BPH). While drug treatment can improve or alleviate symptoms, it may not be entirely effective depending on the progression of benign prostatic hyperplasia (BPH). In TUR-P, an endoscope equipped with an electrosurgical unit is inserted into the urethra to remove enlarged prostate tissue (adenoma) along with the urethral mucosa. When performing TUR-P, the patient is given either lower body or general anesthesia. Furthermore, because TUR-P involves removing enlarged prostate tissue as described above, if the enlargement is significant, bleeding during the procedure can be relatively large, and in some cases, a blood transfusion may be necessary. Therefore, TUR-P places a relatively heavy burden on the patient. In relation to the above issues, for example, Patent Document 1 proposes a medical device that aims to improve or alleviate the symptoms of benign prostatic hyperplasia through a transurethral approach. The medical device described in Patent Document 1 comprises a shaft assembly that can be inserted into the urethra, a needle delivered into the urethra via the shaft assembly, and an anchor assembly (wire-like structure) that is positioned to bridge the gap between the urethra and the outer portion of the prostate (outer surface of the prostatic capsule), generating tension to widen the urethra. In the treatment method using the medical device described in Patent Document 1, a shaft assembly is inserted into the urethra through the external urethral orifice, a needle is delivered into the urethra through the lumen of the shaft assembly, and the needle is punctured from within the urethra toward the outer portion of the prostate. Then, an anchor assembly is placed between the urethra and the outer portion of the prostate through the perforation created by the needle. According to the above procedure, while the anchor assembly is implanted in the patient's body, the tension of the anchor assembly maintains a physically expanded state of the patient's urethra. Therefore, compared to drug therapy, it is possible to effectively improve and alleviate the condition of urethral compression caused by an enlarged prostate. Furthermore, compared to TUR-P (transurethral resection of prostate tissue), the above procedure can reduce blood loss during the procedure, thus reducing the burden on the patient. WO2010/014821 This is a simplified perspective view showing an example of the use of a medical device according to the embodiment.This is a longitudinal cross-sectional view of the first magnet according to the embodiment, taken along its longitudinal direction.This is a cross-sectional view of the first magnet along the line 3A-3A shown in Figure 2.This is a schematic diagram illustrating a method for implanting (implanting) a medical device according to an embodiment.This is a schematic diagram illustrating a method for implanting (implanting) a medical device according to an embodiment.This is a schematic cross-sectional view along the line 6A-6A shown in Figure 5.This is a diagram illustrating an example (a simulation of a treatment method using a medical device).This is a diagram illustrating an example (a simulation of a treatment method using a medical device).This figure shows the results of an example (simulation of a treatment method using a medical device). The embodiments for carrying out the present invention will be described below with reference to the drawings. The embodiments shown herein are illustrative examples to embody the technical idea of the present invention and do not limit it. Furthermore, all other implementable forms, examples, and operational techniques that can be conceived by those skilled in the art without departing from the spirit of the present invention are included within the scope and spirit of the present invention, as well as within the scope of the invention described in the claims and its equivalents. The drawings attached to this specification may be schematically represented with altered scale, aspect ratios, and shapes from the actual objects for the sake of illustration and ease of understanding. However, these are merely examples and do not limit the interpretation of the present invention. In the following explanations, ordinal numbers such as "1st" and "2nd" are used for convenience only and do not prescribe any particular order, unless otherwise specified. The arrows X1-X2 in the figure indicate the longitudinal direction of the first magnet 110, th