JP-2026075067-A - Sensor guide wire

Abstract

[Problem] To provide a sensor guide wire, a method for manufacturing a sensor guide wire, and a method for using it. [Solution] An exemplary sensor guidewire 100 is a core wire extending between a first end and a second end, the first and second ends defining the length of the sensor guidewire, the core wire and a plurality of wires 101 in a helical structure 102 surrounding the core wire, the helical structure including a plurality of wires extending along at least one subset of the length of the core wire and a plurality of electrodes 103A, 103B, 103C spaced apart from each other along the helical structure, each electrode configured to cover each portion of the helical structure along the length of the sensor guidewire, the electrodes connected to one of the plurality of wires to enable the conduction of signals from the electrodes to the wires, and each electrode and wire defines an electrophysiological sensor. [Selection Diagram] Figure 1

Inventors

• 渡辺 裕文

Assignees

• 朝日インテック株式会社

Dates

Publication Date

20260507

Application Date

20251010

Priority Date

20241021

Claims (20)

1. A sensor guide wire, A core wire extending between a first end and a second end, wherein the first end and the second end define the length of the sensor guide wire, A plurality of wires within a helical structure surrounding the core wire, wherein the helical structure extends along at least one subset of the length of the core wire, A plurality of electrodes spaced apart from each other along the helical structure, Equipped with, Each electrode is configured to cover a portion of the helical structure along the length of the sensor guide wire, Each of the electrodes is connected to one of the plurality of wires, and the connection enables the conduction of signals from the electrode to the one of the plurality of wires. Each of the electrodes and one of the plurality of wires defines an electrophysiological sensor. Sensor guide wire.
2. The sensor guide wire according to claim 1, wherein each electrophysiological sensor defined by the plurality of wires and each pair of the plurality of electrodes is electrically independent of one another.
3. The system further comprises a tip configured to enclose the second end of the core wire and each of the ends of the plurality of wires adjacent to the second end of the core wire, The sensor guide wire according to claim 1, wherein the tip further defines the length of the sensor guide wire.
4. The sensor guide wire according to claim 3, wherein the helical structure is configured to taper towards the tip from a first diameter to a second diameter.
5. The sensor guide wire according to claim 4, wherein the core wire is configured to taper towards the tip from a first diameter to a second diameter.
6. The sensor guide wire according to claim 3, wherein the chip comprises at least one epoxy material.
7. The sensor guide wire according to claim 1, wherein at least one of the plurality of electrodes has a cavity configured to expose a portion of one of the plurality of wires within the helical structure.
8. The plurality of wires comprises at least eight wires, The sensor guide wire according to claim 1, wherein the plurality of electrodes comprises at least eight electrodes.
9. The plurality of wires comprises at least 16 wires, The sensor guide wire according to claim 1, wherein the plurality of electrodes comprises at least 16 electrodes.
10. The sensor guide wire according to claim 1, wherein each of the plurality of wires comprises a platinum-iridium layer configured to impart radiation opacity to the helical structure.
11. The sensor guide wire according to claim 10, wherein the thickness of the platinum-iridium layer is at least 25.0 microns.
12. The sensor guide wire according to claim 10, wherein each of the plurality of wires further comprises a polytetrafluoroethylene (PTFE) layer on the platinum-iridium layer.
13. The sensor guide wire according to claim 12, wherein the thickness of the PTFE layer is at least 33.0 microns.
14. The sensor guide wire according to claim 1, wherein each of the plurality of wires has a diameter of at least 0.25 mm.
15. Each of the aforementioned plurality of electrodes is provided with a platinum layer, The sensor guide wire according to claim 1, wherein the platinum layer makes each of the electrodes radiopaque.
16. The sensor guide wire according to claim 1, wherein the core wire comprises a nickel-titanium alloy.
17. The sensor guide wire according to claim 1, wherein the cross-section of the core wire has a quadrilateral shape.
18. The plurality of electrodes define their respective sections that extend along the length of the sensor guide wire. The aforementioned sensor guide wire is The sensor guide wire according to claim 1, further comprising at least one additional wire configured to wrap around each section of the sensor guide wire.
19. The sensor guide wire according to claim 1, wherein the length of the sensor guide wire is at least 80.0 mm.
20. The sensor guide wire according to claim 1, wherein the separation distance between each of the plurality of electrodes is at least 10.0 mm.

Description

This application generally relates to sensor guide wires and methods for using sensor guide wires. Electrodes are sometimes used to measure bioelectricity within a subject's body. For example, electrodes may be placed around the skull of a subject to measure electrophysiological signals generated by the brain. Higher measurement accuracy and specificity can sometimes be achieved by inserting electrodes into the body. However, the tortuous tissues of the body can increase the difficulty of guiding electrodes to the target site. Furthermore, deploying multiple electrodes to a target site can be difficult due to the limited spatial dimensions at the target site and along the insertion path. Existing methods have not yet solved the challenge of deploying robust electrophysiological sensors to desired target sites. Embodiments of this disclosure relate to a sensor guidewire, a kit comprising one or more sensor guidewires, and a method for using a sensor guidewire. An exemplary sensor guidewire of this disclosure comprises a core wire extending between a first end and a second end, the first and second ends defining the length of the sensor guidewire; and a plurality of wires within a helical structure surrounding the core wire, the helical structure comprising a plurality of wires extending along at least one subset (at least a portion of the length of the core wire); and a plurality of electrodes spaced apart from each other along the helical structure, each electrode configured to cover each portion of the helical structure along the length of the sensor guidewire; each electrode connected to one of the plurality of wires, the connection enabling the conduction of a signal from the electrode to one of the plurality of wires; and each electrode and one of the plurality of wires defining an electrophysiological sensor. In some embodiments, each electrophysiological sensor, defined by a pair of wires and electrodes, is electrically independent of one another. In some embodiments, the sensor guidewire further comprises a tip configured to enclose a second end of the core wire and each end of a plurality of wires adjacent to the second end of the core wire, the tip further defining the length of the sensor guidewire. In some embodiments, the helical structure is configured to taper from a first diameter to a second diameter towards the tip. In some embodiments, the core wire is configured to taper towards the tip from a first diameter to a second diameter. In some embodiments, the tip comprises at least one epoxy material. In some embodiments, at least one of the plurality of electrodes has a gap configured to expose a portion of one of the plurality of wires in the helical structure. In some embodiments, the plurality of wires comprises at least eight wires, and the plurality of electrodes comprises at least eight electrodes. In some embodiments, the sensor guide wire further comprises at least sixteen wires, and the plurality of electrodes comprises at least sixteen electrodes. In some embodiments, each wire of the plurality of wires comprises a platinum-iridium layer configured to impart radiopaqueness to the helical structure. In some embodiments, the thickness of the platinum-iridium layer is at least 25.0 microns. In some embodiments, each wire of the plurality of wires further comprises a polytetrafluoroethylene (PTFE) layer on the platinum-iridium layer. In some embodiments, the thickness of the PTFE layer is at least 33.0 microns. In some embodiments, each wire of the plurality of wires has a diameter of at least 0.25 mm. In some embodiments, each electrode of the plurality of electrodes comprises a platinum layer, the platinum layer making each electrode radiopaque. In some embodiments, the core wire comprises a nickel-titanium alloy. In some embodiments, the cross-section of the core wire has a quadrilateral shape. In some embodiments, the plurality of electrodes define respective sections extending along the length of the sensor guide wire, and the sensor guide wire further comprises at least one additional wire configured to wrap around each section of the sensor guide wire. In some embodiments, the length of the sensor guide wire is at least 80.0 mm. In some embodiments, the separation distance between each of the plurality of electrodes is at least 10.0 mm. In some embodiments, the separation distance between the first electrode of the plurality of electrodes and the last electrode of the plurality of electrodes is at least 150.0 mm. An exemplary sensor guidewire kit may comprise a first sensor guidewire and a second sensor guidewire as described in the claims, wherein the plurality of electrodes of the first sensor guidewire are spaced apart from each other by a first separation distance, and the plurality of electrodes of the second sensor guidewire are spaced apart from each other by a second separation distance different from the first separation distance, and at least one computing device config