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JP-2026514283-A - Device body for drug delivery device, assembly for drug delivery device, and drug delivery device

JP2026514283AJP 2026514283 AJP2026514283 AJP 2026514283AJP-2026514283-A

Abstract

A device body for a drug delivery device is provided. The device body includes a needle cover positioning structure configured to fix the needle cover of the drug delivery device to axial movement relative to the device body by interacting with at least one corresponding fixed feature portion of the needle cover when the needle cover is in the needle cover position relative to the device body. The device body has a proximal end and a distal end. In the needle cover position, the needle cover protrudes distally beyond the device body. The device body further includes a first needle cover safety structure configured and positioned to prevent separation of the fixed feature portion from the needle cover positioning structure by interacting with the outer surface of the needle cover when the portion of the device body on which the needle cover positioning structure is located is deformed.

Inventors

  • サイモン・フランシス・ブリアトン
  • ルウィーズ・ホジソン
  • トーマス・マーク・ケンプ
  • ケヴィン・ラヌチ
  • ヒューゴー・リヴェラット
  • ウィリアム・ティミス

Assignees

  • サノフイ

Dates

Publication Date
20260508
Application Date
20231031
Priority Date
20221031

Claims (20)

  1. A device body (700) for a drug delivery device (100), A needle cover positioning structure (720, 724) is configured to fix the needle cover (500) of a drug delivery device to axial movement relative to the device body (700) by interacting with at least one corresponding fixing feature portion (505, 510) of the needle cover (500) when the needle cover (500) is in the needle cover position (Z) relative to the device body (700). Includes, It has a proximal end and a distal end, At the needle cover position (Z), the needle cover (500) protrudes distally beyond the device body (700). The device body (700) further includes a first needle cover safety structure (720.1) configured and positioned to prevent separation of the fixed feature portion (505, 510) and the needle cover positioning structure (720, 724) by interacting with the outer surface of the needle cover (500) when the portion of the device body (700) on which the needle cover positioning structure (720, 724) is located is deformed.
  2. The device body (700) according to claim 1, wherein the first needle cover safety structure (720.1) is a projection extending radially inward from the inner surface of the device body (700).
  3. The device body (700) according to claim 2, wherein the radial inward extension of the projection decreases in the proximal direction (P) along the axial extension of the projection.
  4. The first needle cover safety structure (720.1) extends axially, for example, in the proximal direction (P), from the proximal end of the needle cover positioning structure (720, 724), as described in any one of claims 1 to 3, the device body (700).
  5. The portion of the device body (700) is the distal portion of the device body (700) according to any one of claims 1 to 4.
  6. The device body (700) according to any one of claims 1 to 5, wherein the first needle cover safety structure (720.1) is configured to restrict the radial movement of the outer surface of the needle cover (500) relative to the inner surface of the device body (700).
  7. The device body (700) according to any one of claims 1 to 6, wherein the needle cover positioning structure (720, 724) includes at least one, preferably at least four, ribs extending radially inward from the inner surface of the device body (700), for example, the side wall.
  8. The device body (700) according to any one of claims 1 to 7, further comprising at least one proximal stopper structure (721) that, when the needle cover (500) is moved proximal to the device body (700), interacts with a rear stopper feature of the needle cover (500) to determine the maximum proximal position of the needle cover (500) relative to the device body (700).
  9. The device body (700) according to any one of claims 1 to 8, further comprising a central support structure (701) configured to support a drug container (900), for example, a pre-filled syringe (900) and/or a container holder (800), for example, a syringe holder (800).
  10. The central support structure (701) is connected to the side wall of the device body (700) via at least one, preferably four, connecting elements (708), such as connecting ribs (708). The device body (700) according to claim 9, wherein the connecting element (708) extends along at least 50% of the axial length of the central support structure (701).
  11. The device body (700) according to claim 10, wherein the radially inner portion of the connecting element (708) is shorter in the axial direction than the radially outer portion of the connecting element (708), and as a result, at least the distal surface of the radially outer portion protrudes distally beyond the distal surface of the radially inner portion.
  12. A device body (700) according to any one of claims 1 to 11, further comprising a holder guide structure (726), for example, at least one holder guide rib (726), preferably four holder guide ribs (726), configured to interact with the container holder (800) and/or the body closure (1200) of the drug delivery device (100) to restrict the rotational movement of the container holder (800) and/or the body closure (1200) relative to the device body (700).
  13. The device body (700) according to claim 12, further comprising a needle cover rotation prevention structure (723) configured to prevent the rotation of the needle cover (500) relative to the device body (700) through interaction with the rotation prevention feature portion of the needle cover (500).
  14. The device body (700) according to claim 13, wherein the needle cover rotation prevention structure (723) includes projections extending circumferentially and radially from at least one of the connecting elements (708), thereby forming a rotation prevention surface for interacting with the rotation prevention feature portion of the needle cover (500).
  15. The device body (700) according to claim 13 or 14, further comprising a second needle cover safety structure (722) configured and positioned to prevent the rotation-preventing feature from detaching from the rotation-preventing structure (723) by interacting with the inner surface of the needle cover (500).
  16. The device body (700) according to any one of claims 1 to 15, wherein the needle cover position is the first or last needle cover position.
  17. An assembly for a drug delivery device, A device body (700) according to any one of claims 1 to 16, Needle cover (500) and An assembly including a needle cover spring (600).
  18. A device body (700) according to any one of claims 1 to 16 or an assembly according to claim 17, A drug delivery device (100) including a drug container (900) for containing a drug (Dr).
  19. A drug delivery device (100) according to claim 18, which is an auto-injector and/or a pen-type device.
  20. A method for delivering a drug from a drug delivery device, comprising using the drug delivery device (100) described in claim 18 or 19.

Description

Drug delivery devices offer a convenient option for administering medications to users/patients. For example, drug delivery devices are safer than traditional syringes in terms of human error. Due to increasing demand, handheld drug delivery devices require mass production. Reducing manufacturing costs and increasing production speed are ongoing challenges, where user safety plays a crucial role. Figure 1A-1D shows cross-sectional views of a drug delivery device in different operating states according to the first embodiment.This is an exploded view of an example of a drug delivery device, with or without an optional separate syringe holder.Any cap and any cap cover.Any cap and any cap cover.Any cap and any cap cover.Any cap and any cap cover.Any cap and any cap cover.Any cap and any cap cover.Any cap and any cap cover.Any cap and any cap cover.Any cap and any cap cover.These are perspective views and cross-sectional views of an arbitrary graba, respectively.These are perspective views and cross-sectional views of an arbitrary graba, respectively.This is an exemplary embodiment of a single sheet capable of forming a grabber carrier.This is a grabber that engages with the syringe needle shield.This is a grabber that engages with the syringe needle shield.This is a cutaway view of the grabber from the previous embodiment, assembled inside the cap.This details the interaction between grabber-holding bosses, for example, between the boss of a cap and the opening of an exemplary grabber.This is a cross-sectional view of the front end of an injection device having a fitted cap and a grabber mounted on the cap that interacts with the needle shield.This is any needle cover (needle shroud).This is the needle cover spring.This is a cross-sectional view of the needle cover spring assembled inside the drug delivery device in its pre-use state.This is the device itself.This is a cross-sectional view of the device itself.This is a perspective cross-sectional view of the distal end of the device body.This is a cross-sectional view of the central portion of the device body having a syringe holder.This is a perspective view of the syringe holder front stopper on the device body.This is a cross-sectional view of the distal end of the device body with the needle cover in the third cover position.This is a perspective view of the needle cover locking structure interacting with the flexible arm of the needle cover.Any syringe holder.A perspective view of any syringe holder.This is a detail diagram of a further exemplary embodiment of the flexible holder arm.This is an arbitrary syringe holder including the flexible holder arm shown in Figure 8C.Any pre-filled syringe.It's a plunger.This is the plunger release mechanism in its first state.This is the plunger release mechanism in its second state.This is the plunger release mechanism during the assembly of the drive subassembly.This is the plunger release mechanism during final assembly.This is a further state of the plunger release mechanism.This is a schematic diagram of the plunger release mechanism after the sleeve has been pushed into the retracted position.This is a schematic detail diagram of the plunger release mechanism after final assembly, before the sleeve is pushed in.This is a schematic detail diagram of the plunger release mechanism while the sleeve is being pushed in.This is a longitudinal rib located on the inside of the rigid arm of the drive spring holder.This is a perspective view of the plunger according to the second embodiment.This is a distal view of the plunger according to the second embodiment.This is a cross-sectional view along the radial direction through the shaft of the plunger according to the second embodiment.This is a cross-sectional view along the longitudinal direction through which the plunger shaft passes.This is a drive spring according to one embodiment of the present disclosure.This is the drive spring shown in Figure 11A, which is incorporated into the drug delivery device and operates the plunger.These are the drive springs shown in Figures 11A and 11B, which are assembled within the drug delivery device, before the plunger is activated.This is a perspective view of the drive spring holder.This is a perspective view of the drive spring holder.This is a syringe return prevention mechanism.This is a cross-sectional view of the proximal portion of the drive spring holder.This is a different embodiment of the flexible portion of the drive spring holder.This is a different embodiment of the flexible portion of the drive spring holder.This is a different embodiment of the flexible portion of the drive spring holder.It is any audible indicator (clicker).An example is an indicator holder included on a drive spring holder.This is a perspective view of the support structure at the distal end of the flexible support arm.This is a perspective view of the guide structure of the indicator holder.This is a cross-sectional view of the indicator holder