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JP-2026514329-A - Intraocular lens with haptic separation structure

JP2026514329AJP 2026514329 AJP2026514329 AJP 2026514329AJP-2026514329-A

Abstract

This specification discloses an intraocular lens comprising an optical portion and at least one haptic having a proximal and distal end coupled to the optical portion. The haptic includes a haptic internal passage extending over at least a portion of the haptic. The haptic may include one or more haptic isolation means disposed within the haptic internal passage. The one or more haptic isolation means may be configured to counteract or mitigate unintended shape changes caused by external energy directed at the haptic.

Inventors

  • アンドリュー アール．ワルツ
  • グレゴリー ビントン マシューズ
  • スティーブン コリンズ
  • ラザ ウラブディン シャー
  • ハンヤン ホアン
  • ウィリアム ドーラ
  • ポール ミッセル

Assignees

  • アルコン インコーポレイティド

Dates

Publication Date
20260511
Application Date
20240325
Priority Date
20230327

Claims (20)

  1. It is an intraocular lens, Optical parts including optical fluid chamber, An intraocular lens comprising a haptic having a proximal end coupled to the optical portion and a distal end, the haptic including a haptic internal passage extending through at least a portion of the haptic and in fluid communication with the optical fluid chamber, and a plurality of haptic isolation means disposed within the haptic internal passage.
  2. The intraocular lens according to claim 1, wherein the haptic internal passage is surrounded by a haptic radially lateral wall, a haptic radially lateral wall, a haptic anterior wall, and a haptic posterior wall.
  3. The intraocular lens according to claim 2, wherein the haptic isolation means is configured to restrict any radial movement of the radially outer wall of the haptic to 0 to 10 microns in response to a laser beam directed at the haptic.
  4. The intraocular lens according to claim 2, wherein the haptic separation means extends from the anterior wall of the haptic to the posterior wall of the haptic.
  5. The intraocular lens according to claim 2, wherein each of the haptic isolation means includes a side surface, and none of the side surfaces of the haptic isolation means physically contacts the haptic radially inner wall or the haptic radially outer wall.
  6. The intraocular lens according to claim 2, wherein the haptic separation means is positioned radially closer to the radially inner wall of the haptic than to the radially outer wall of the haptic.
  7. The intraocular lens according to claim 6, wherein at least one side of the haptic isolation means closest to the haptic radially medial wall is separated from the haptic radially medial wall by an internal isolation distance, and another side of the haptic isolation means closest to the haptic radially lateral wall is separated from the haptic radially lateral wall by an external isolation distance, the external isolation distance being 1.5 × to 3 × greater than the internal isolation distance.
  8. The intraocular lens according to claim 1, wherein at least one of the haptic separation means is configured as a cylinder.
  9. The intraocular lens according to claim 8, wherein the cylinder has a substantially circular cross-section.
  10. The intraocular lens according to claim 1, wherein at least one of the haptic separation means has a substantially rectangular cross-section, a substantially triangular cross-section, or a substantially elliptical cross-section.
  11. The intraocular lens according to claim 1, wherein the plurality of haptic separation means are arranged as a curved colonnade within the haptic internal passage.
  12. The intraocular lens according to claim 1, wherein the plurality of haptic separation means are arranged at regular intervals along at least one section of the haptic internal passage.
  13. The intraocular lens according to claim 1, wherein the haptic includes 3 to 20 haptic separation means.
  14. Each of the haptic isolation means includes an isolation means front end, an isolation means rear end, and an isolation means section between the isolation means front end and the isolation means rear end, wherein the width or diameter of at least one of the isolation means front end and the isolation means rear end is greater than the isolation means section between the isolation means front end and the isolation means rear end, as described in claim 1.
  15. The intraocular lens according to claim 1, wherein the width or diameter of at least one of the haptic isolation means remains constant along the length or height of the haptic isolation means.
  16. Each of the haptic isolation means is measurable by its width or diameter and its length or height, and the length or height of at least one of the haptic isolation means is more than twice its width or diameter, according to claim 1.
  17. The intraocular lens according to claim 1, wherein the haptic isolation means are arranged in an arc shape, and the haptic isolation means includes the most distal haptic isolation means and the most proximal haptic isolation means, which act as the endpoints of the arc, and the arc is measurable by a central angle or arc angle, and the central angle or arc angle is between 70 and 74 degrees.
  18. The intraocular lens according to claim 1, wherein the haptic comprises at least one of an internal passage filler and an internal passage expander made of a composite material, the composite material is configured to expand in response to receiving laser light directed towards the internal passage filler or the internal passage expander, and the haptic isolation means is not made of the composite material.
  19. It is an intraocular lens, optical part, An intraocular lens comprising a haptic having a proximal end coupled to the optical portion and a distal end, the haptic including an internal haptic passage extending through at least a portion of the haptic, and a plurality of haptic isolation means arranged in an arc configuration within the internal haptic passage.
  20. It is an intraocular lens, optical part, A haptic having a proximal end coupled to the optical portion and a distal end, and including an internal haptic passage extending through at least a portion of the haptic; and an intraocular lens comprising one or more isolation blocks disposed within the internal haptic passage, wherein at least one of the one or more isolation blocks includes a non-circular cross-section.

Description

Cross-reference of related applications: This application claims priority to U.S. Patent Application No. 63/492,430, filed on 27 March 2023, and U.S. Patent Application No. 63/492,435, filed on 27 March 2023, the entire contents of which are incorporated herein by reference. This disclosure relates generally to the field of intraocular lenses, and more specifically to adjustable intraocular lenses. Cataracts are a condition in which the normally clear lens of a patient's eye becomes cloudy. Cataracts develop as a result of aging, genetic factors, trauma, inflammation, metabolic disorders, or radiation exposure. Age-related cataracts are the most common type of cataract. In the treatment of cataracts, the surgeon removes the natural lens matrix from the patient's lens capsule and replaces it with an intraocular lens (IOL). Conventional IOLs provide one or more selected focal lengths that allow the patient to see distant objects. However, after cataract surgery, patients who have had conventional IOLs implanted often need glasses or other corrective eyewear to perform certain activities because the eye is no longer able to maintain a clear image of objects or adjust to focus on objects as the distance changes (i.e., change its refractive power). Newer IOLs, such as accommodative IOLs, can restore at least some degree of focusing ability to the eye. Accommodative IOLs (AIOLs) utilize the available power within the eye to readjust the eye's focus to distant or near targets by altering a portion of the optical system. In addition, IOLs may need adjustment after surgery or implantation into the patient's eye. In some cases, implanted IOLs can be adjusted using laser treatment. Figure 1A shows a top view of one embodiment of an IOL including a haptic with haptic separation means.Figures 1B and 1C show cross-sectional views of the IOL along section A-A in Figure 1A.Figure 2A shows a portion of the haptics of an IOL without haptic isolation means.Figure 2B is a graph showing the movement of the radial outer wall of a haptic without a haptic separation mechanism and the movement of the radial outer wall of a haptic equipped with a haptic separation mechanism.Figure 3 shows a cross-sectional view of the haptic including the haptic separation means.Figure 4A shows a perspective view of one embodiment of the haptic, including a haptic separation mechanism, with the front portion of the haptic removed for clarity. Figure 4B shows a top view of another embodiment of the haptic, including a haptic separation mechanism.Figure 5A shows a perspective view of the haptic, including the haptic separation means.Figure 5B shows the haptic from Figure 5A with its distal end removed to illustrate a cross-section of a portion of the haptic.Figure 6 shows a computed tomography (CT) scan image of a portion of a haptic, including a haptic separation mechanism, in which the haptic radial outer wall has been digitally removed.Figure 7A shows a perspective view of another embodiment of the haptic, including a different type of haptic isolation means, with the front portion of the haptic removed for clarity.Figure 7B shows a perspective view of yet another embodiment of the haptic, including another type of haptic separation means, with the front portion of the haptic removed for clarity. Figure 1A shows a top view of one embodiment of IOL 100, including a haptic 104 with a haptic isolation means 105. In some embodiments, IOL 100 can be an adjustable IOL, such as an accommodative IOL (AIOL). IOL 100 can be implanted in a patient's eye to correct defocus aberration, corneal astigmatism, spherical aberration, or a combination thereof. The IOL 100 may include an optical portion 102 and one or more haptics 104, including a first haptic 104A and a second haptic 104B coupled to the optical portion 102 and extending along its periphery. The IOL 100 can be positioned within the natural lens capsule after the natural lens has been removed. The optical portion 102, when implanted in the natural lens capsule, can be configured to refract light entering the eye towards the retina. One or more haptics 104 can be configured to engage with the lens capsule and deform in response to ciliary muscle movements (e.g., muscle relaxation, muscle contraction, or a combination thereof) in relation to the reshaping of the lens capsule. Each of the haptic 104 may include a haptic internal passage 106 extending through at least a portion of the haptic 104. For example, the first haptic 104A may include a first haptic internal passage 106A extending through at least a portion of the first haptic 104A, and the second haptic 104B may include a second haptic internal passage 106B extending through at least a portion of the second haptic 104B. The haptic internal passage 106 (e.g., either the first haptic internal passage 106A or the second haptic internal passage 106B) can be in fluid communication with or fluidly connected to the optical portion fluid chamber 108 within