JP-7854900-B2 - Pore-cleansing agent

Inventors

• 越知 貴夫

Assignees

• 長谷川香料株式会社

Dates

Publication Date

20260507

Application Date

20220901

Claims (2)

1. A pore-improving agent comprising a composition containing (A) a hydrogenated phospholipid derived from soybeans with an acid value of 5 mg KOH/g or more and (B) 1,2-pentanediol , wherein the content of component (B) exceeds 100 parts by mass of a lipid membrane structure relative to 100 parts by mass of component (A), The aforementioned lipid structure, when dispersed in the aqueous phase, spontaneously disperses as a lipid structure with an average hydrodynamic diameter of 200 nm or less. A pore-improving agent that has one or more pore-improving effects selected from the group consisting of pore-reducing effect, sebum secretion regulation effect, comedone lifting/detachment effect, comedone formation inhibition effect, acne-soothing effect, acne occurrence inhibition effect, blackhead improvement effect, makeup application improvement effect, and makeup longevity improvement effect.
2. The pore-improving agent according to claim 1, wherein the lipid membrane structure is a single-layer lamellar structure.

Description

This invention relates to a pore-improving agent that forms a lipid membrane structure containing specific phospholipids. Pore-related skin concerns, such as visible pores and acne, consistently rank among the top concerns in various consumer surveys every year. Traditional care for visible pores includes physical removal of blackheads using sheet masks or tools, tightening with astringents, and dissolving/removing blackheads with cleansing products containing solvents, surfactants, or scrubs. However, these methods are often ineffective or only provide temporary relief despite the significant burden on the skin. The more you use these methods, the more stress accumulates on the skin, leading to further skin problems. Regarding acne, there has been an increase in recent years in acne caused by the rapid changes in the skin environment and physical irritation, often referred to as "mask irritation." Preventing acne is difficult, and while existing acne can only be treated with medical procedures and medications, this can lead to scarring and side effects from medications, such as dryness and skin irritation, resulting in further skin problems. To date, as a pore-improving agent for reducing the appearance of pores and acne, for example, Patent Document 1 discloses a keratinization inhibitor, pore-reducing agent, or skin roughness prevention/improvement agent comprising one or more compounds selected from the group consisting of specific β-alanine derivatives and their salts. Furthermore, Patent Document 2 reports that the appearance of pores can be effectively improved by using a combination of specific plant extracts and retinol-based components such as retinol and retinol derivatives. On the other hand, Patent Document 3 reports that lipid membrane structures mainly composed of phospholipids are useful in skincare as carriers for active ingredients, but they are not known to be useful as pore-improving agents. Japanese Patent Publication No. 2012-21026Japanese Patent Publication No. 2014-227374Patent No. 6778306 This is a photograph of the lipid membrane structure formed in Example 5, observed using cryo-electron microscopy (Cryo-TEM). The following describes in detail embodiments for carrying out the present invention (hereinafter also referred to as "this embodiment"). It should be noted that the present invention is not limited to this embodiment and can be implemented in various modifications within the scope of its gist. The pore-improving agent of this embodiment is a pore-improving agent comprising a composition containing a lipid membrane structure formed by phospholipids with an acid value of 5 mg KOH/g or higher (hereinafter also referred to as the "lipid membrane structure-containing composition"). In this specification, "lipid membrane structure" refers to particles having a lamellar (lipid bilayer) structure in which lipid molecules are arranged with their hydrophilic groups facing outwards and their hydrophobic groups facing each other. Specific examples of such structures are those described in the section on <Lipid Membrane Structure-Containing Compositions> below. Furthermore, in this specification, a lipid membrane structure is considered to have been formed if the average hydrodynamic diameter of a lipid membrane structure-containing composition prepared using a lipid membrane structure-forming composition can be measured using a dynamic light scattering measurement device, more specifically, a Zetasizer Nano ZSP (Malvern Instruments). <Composition for forming lipid membrane structure> The lipid membrane structure-forming composition in this embodiment is a composition for obtaining a lipid membrane structure-containing composition. The components of the lipid membrane structure-forming composition will be described below. [Component (A)] The lipid membrane structure-forming composition in this embodiment contains, as component (A), a phospholipid with an acid value of 5 mg KOH/g or more. The phospholipid with an acid value of 5 mg KOH/g or more may be one or two or more types, or it may be a combination of one or more phospholipids with an acid value of less than 5 mg KOH/g and one or more phospholipids with an acid value of 5 mg KOH/g or more to obtain an acid value of 5 mg KOH/g or more. The origin of the phospholipid is not particularly limited, but lecithin is especially preferred because it is naturally derived and suitable for use in cosmetics and topical skin preparations. Lecithin may be derived from soybeans, egg yolks, rapeseed, sunflowers, corn, etc., and is preferably plant-derived, such as soybeans, rapeseed, sunflowers, or corn. Soybean-derived lecithin is even more preferred due to its availability and quality stability. As for the phospholipid, hydrogenated phospholipids are preferred from the viewpoint of preventing oxidative degradation due to heating processes in the manufacturing of cosmetics and quasi-drugs, and oxidative degradation during storage of these products