JP-7856845-B2 - Heart valve stents and artificial heart valves

Inventors

• 梁向斌
• 鐘偉
• 王松

Assignees

• 上海以心医療器械有限公司

Dates

Publication Date

20260511

Application Date

20230630

Priority Date

20220712

Claims (11)

1. The structure comprises a support body and at least one protruding extension branch structure connected to the support body, wherein a flow passage for blood is defined in the support body, the protruding extension branch structure extends from the support body outward from the flow passage, the protruding extension branch structure has a protruding extension portion that can contact cardiac tissue, and a gap is formed between the protruding extension branch structure and the support body for accommodating the heart's own valve leaflets. The support body includes a plurality of support units, and the flow passage is defined and formed by the plurality of support units. Each of the support units includes two first support structures for connecting to different valve leaflets, and a second support structure connected to the two first support structures, with a space formed between the two first support structures and the second support structure that can be covered by connecting a cover member. If we define the upstream and downstream directions along the direction in which blood flows through the flow passage, then the second support structure is located upstream of the two first support structures. The two first support structures each extend downstream from both ends of the second support structure, and the two first support structures merge and connect to each other. Each of the support units is connected to the protruding extension branch structure, and the protruding extension branch structure is located between two adjacent support units in the circumferential direction of the support body. Each of the support units is connected to two of the protruding extension branch structures, and the two protruding extension branch structures between two adjacent support units are connected to each other. A heart valve stent characterized by the following features.
2. Along the direction in which blood flows through the flow passage, the protruding extension branch structure includes a continuous protruding extension segment and a connecting segment. The protruding extended segment is bent and extended in a direction away from the flow passage, the connecting segment has one end connected to the protruding extended segment and the other end connected to the support body, and the angle formed between the protruding extended segment and the axial direction of the flow passage is between 1° and 150°. The cardiac valve stent according to claim 1, characterized in that the horizontal distance (a) between the end of the connecting segment that connects to the protruding extension segment and the support body located upstream of the flow passage is 1 mm to 20 mm.
3. The cardiac valve stent according to claim 2, characterized in that the two protruding extension branch structures between two adjacent support units are formed from a single braided wire.
4. A connecting ring is formed on the downstream portion of the first support structure. The cardiac valve stent according to feature 1 .
5. Each of the first support structures has the connecting ring formed on it. The cardiac valve stent according to feature 4 .
6. A first rivet knotting structure is provided upstream of the connecting ring, and the connecting ring is formed as a closed ring by the first rivet knotting structure. The cardiac valve stent according to feature 4 .
7. Each of the support units is connected to its adjacent support unit by a rivet structure to form a second rivet-connected structure, in which the first support structure and the second support structure of two adjacent support units are arranged in parallel, and the gap for accommodating the heart's own valve leaflets is formed between the protruding extension branch structure and the first support structure and the second support structure in the second rivet-connected structure. The cardiac valve stent according to feature 1 .
8. The two first support structures of each support unit are connected by a rivet structure to form a third rivet connection structure. The cardiac valve stent according to feature 1 .
9. A cardiac valve stent according to claim 1 , A valve leaflet provided within the flow passage and connected to the first support structure of the heart valve stent, An artificial heart valve characterized by comprising: a first sealing cover member which is installed in and connected to the space formed between the two first support structures and the second support structure of the heart valve stent, and which covers the space.
10. The system further includes a second sealing cover member that is installed to surround the outer circumference of the heart valve stent , The artificial heart valve according to claim 9 , characterized in that the second sealing cover member is disc-shaped, and the outer peripheral edge of the second sealing cover member is bent downstream of the heart valve stent to form a protruding edge.
11. The artificial heart valve according to claim 9 , characterized in that the material of the valve leaflet is at least one of polymer materials, biomaterials, and tissue engineering materials.

Description

This disclosure belongs to the technical field of medical devices and specifically relates to cardiac valve stents and prosthetic cardiac valves. (Cross-reference of related applications) This disclosure relates to a Chinese patent application filed with the China Patent Office on July 12, 2022, with application number CN202210820044.3 and title "Implantable cardiac valve stent and cardiac prosthetic valve", a Chinese patent application filed with the China Patent Office on July 12, 2022, with application number CN202210820049.6 and title "Cardiac valve stent and cardiac prosthetic valve", and a Chinese patent application filed with the China Patent Office on July 12, 2022 Priority is claimed based on the Chinese application filed with the National Patent Office, application number CN202210822410.9, titled "Artificial Heart Valve Stent and Artificial Heart Valve," and the Chinese application filed with the National Patent Office on March 3, 2023, application number CN2023102038996, titled "Artificial Heart Valve Stent and Artificial Heart Valve," the entire contents of which are incorporated by reference in this disclosure. Heart valves are located between the atria and ventricles, and between the ventricles and the aorta, and function as unidirectional valves for the one-way flow of blood. The four valves in the human body are called the mitral valve, tricuspid valve, aortic valve, and pulmonary valve. If these valves become diseased (e.g., narrowed or insufficient), it affects blood flow, leading to abnormalities in cardiac function and ultimately heart failure. Currently, when a heart valve is affected, treatment often involves valve replacement surgery, which means replacing it with an artificial mechanical valve or a bioprosthetic valve. However, conventional heart valve stents are prone to dislodgement due to blood flow after implantation, have relatively poor stability during attachment and fixation, shorten the lifespan of the artificial heart valve, increase the risk of the patient needing valve replacement again, and some heart valve stents are prone to coronary artery blockage after implantation. This disclosure provides a cardiac valve stent. The cardiac valve stent comprises a support body and at least one protruding extension branch structure connected to the support body, wherein a blood flow passage is defined in the support body, the protruding extension branch structure extends outward from the support body to the outside of the flow passage, the protruding extension branch structure has a protruding extension portion that can contact cardiac tissue, and a gap is formed between the protruding extension branch structure and the support body for accommodating the cardiac valve leaflets. Optionally, the support body includes a plurality of support units, and the flow passage is defined and formed by the plurality of support units. Each of the support units includes two first support structures for connecting to different valve leaflets, and a second support structure connected to the two first support structures, with a space formed between the two first support structures and the second support structure that can be covered by connecting a cover member. This disclosure further provides another type of heart valve stent. The heart valve stent is formed by weaving together at least one elongated material into a defined shape, and the heart valve stent has a defined blood flow passage, with at least one of the elongated material members extending outward from the flow passage to form a protruding extension that can contact cardiac tissue. Optionally, the heart valve stent includes a plurality of support units, and the flow passage is defined and formed by the plurality of support units. Each of the support units includes two first support structures for connecting to different valve leaflets, and a second support structure connected to the two first support structures, with a space formed between the two first support structures and the second support structure that can be covered by connecting a cover member. Optionally, if upstream and downstream directions are defined along the direction in which blood flows through the flow passage, the second support structure is located upstream of the two first support structures. Optionally, the two first support structures extend downstream from both ends of the second support structure, and the two first support structures are joined and connected. Optionally, the two first support structures extend downstream from both ends of the second support structure, and the second ends of the two first support structures are connected to each other. Optionally, each of the support units is connected to the protruding extension branch structure, and the protruding extension branch structure is located between two adjacent support units in the circumferential direction of the support body. Optionally, each support unit is connected to two of the protruding exten