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KR-102960735-B1 - Cosmetic Composition for Acne Prevention and Method the Same

KR102960735B1KR 102960735 B1KR102960735 B1KR 102960735B1KR-102960735-B1

Abstract

The composition of the present invention is a cosmetic composition for preventing and improving acne, characterized by being composed of an aqueous phase component and an oil phase component in addition to active ingredients, namely Centella asiatica extract, polydeoxyribonucleotide, Styrax japonica extract, green tea extract, Terminalia chebula extract, Cinnamomum camphora leaf extract, palmitoyl tripeptide-1, aloe extract, Gastrodia elata extract, natural flower complex, and fragrance. A method for preparing a cosmetic composition for preventing and improving acne, characterized by comprising: a first step of preparing an aqueous ( H₂O )-based component; a second step of preparing an oil-based component; a third step of mixing and homogenizing the aqueous and oil-based components; and a fourth step of mixing and homogenizing an active ingredient.

Inventors

  • 최경석
  • 김시윤

Assignees

  • (주)케이에스코리아

Dates

Publication Date
20260508
Application Date
20231129

Claims (7)

  1. A cosmetic composition for preventing and improving acne comprising, as active ingredients, Centella asiatica extract, polydeoxyribonucleotide, Styrax japonica extract, green tea extract, Terminalia chebula fruit extract, Spiraea japonica leaf extract, palmitoyl tripeptide-1, aloe extract, Gastrodia elata extract, natural flower complex, fragrance, and aqueous and oil phase components, The above aqueous component comprises purified water 45-50 (w/w), butylene glycol 9-11 (w/w), glycerin 4-6 (w/w), thickener 0.1-1 (w/w), allantoin 0.05-0.15 (w/w), 1,2-hexanediol 1-3 (w/w), EDTA-2NA 0.02-0.04 (w/w), and hyaluronic acid 0.5-1.5 (w/w). A cosmetic composition for preventing and improving acne, characterized in that the above-mentioned oil phase component comprises cetyl alcohol 1-3 (w/w), hydrogenated polydecene 4-6 (w/w), caprylic/capric triglyceride 2-4 (w/w), vegetable oil 4-6 (w/w), Aracel 165 1-3 (w/w), Aracel 60 0.5-1.5 (w/w), and glyceryl caprylate 0.4-0.6 (w/w).
  2. A cosmetic composition for preventing and improving acne according to claim 1, characterized in that, as an active ingredient of the composition, the molecular weight of polydeoxyribonucleotide is 1 to 50 K Dalton and the amount used is 0.001 to 0.4% (w/w).
  3. A cosmetic composition for preventing and improving acne according to claim 1, characterized in that, as active ingredients of the composition, it comprises Centella asiatica extract 0.01–0.5 (w/w), Stellaria media extract 0.01–1 (w/w), green tea extract 0.01–1 (w/w), Terminalia chebula extract 0.01–1 (w/w), Corydalis yanhusuo leaf extract 0.01–1% (w/w), Aloe extract 0.1–1 (w/w), Gastrodia elata extract 0.1–1 (w/w), Natural Flower Complex 0.01–1 (w/w), Palmitoyl Tripeptide-1 0.001–0.5% (w/w), fragrance 0.1–0.4 (w/w), and aqueous and oil phase components.
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  5. A first step of preparing an aqueous ( H₂O )-based component, and The second step of preparing oil-based components, and A third step of mixing and homogenizing aqueous and oil phase components, and A method for preparing a cosmetic composition for preventing and improving acne, comprising a fourth step of homogenizing an active ingredient and a fragrance, the active ingredients including Centella asiatica extract, polydeoxyribonucleotide, Styrax japonica extract, green tea extract, Terminalia chebula fruit extract, Ligustrum japonicum leaf extract, palmitoyl tripeptide-1, aloe extract, Gastrodia elata extract, and natural flower complex. In the first step above, the aqueous components, namely purified water, butylene glycol, glycerin, a thickening agent, allantoin, 1,2-hexanediol, EDTA-2NA, and hyaluronic acid, are placed in a dissolution tank, heated to 70–80°C while stirring to completely dissolve the aqueous components, and then transferred to an emulsification tank, In the second step above, the oily components cetyl alcohol, hydrogenated polydecene, caprylic/capric triglyceride, vegetable oil, Aracel 165, Aracel 60, and glyceryl caprylate are placed in an oil-phase dissolution tank and heated to 70–80°C to dissolve them, and then, In the third step above, the aqueous component and the oil component dissolved as described above are mixed, placed in a homogenizer and homogenized at 700 rpm, then stirred at 29–31 rpm for 19–21 minutes at a vacuum of 38–42 cmHg at 74–76°C, and then A method for preparing a cosmetic composition for preventing and improving acne, characterized by cooling the mixture of the aqueous compound and the oil-phase compound of the third step to 39–41°C in the fourth step, adding active ingredients including Centella asiatica extract, polydeoxyribonucleotide, Styrax japonica extract, green tea extract, Terminalia chebula fruit extract, Pogostemon cablin leaf extract, Aloe extract, Gastrodia elata extract, natural flower complex, palmitoyl tripeptide-1, and fragrance, degassing, placing the mixture in a homogenizer and homogenizing it at 1,500–1,700 rpm, stirring for 19–21 minutes at 39–41°C with a vacuum of 38–42 cmHg and 29–31 rpm, and terminating the reaction at 33°C.
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  7. In claim 5, the method for preparing a cosmetic composition for preventing and improving acne is characterized in that the cosmetic composition is formed into one formulation selected from softening lotion, nourishing lotion, nourishing cream, massage cream, essence, eye cream, cleansing cream, cleansing foam, cleansing water, pack, soap, spray, or powder.

Description

Cosmetic Composition for Acne Prevention and Method of Preparation The present invention relates to a cosmetic composition for preventing and alleviating acne and a method for manufacturing the same. More specifically, the main ingredients consist of Centella asiatica extract 0.01–0.5% (w/w), polydeoxyribonucleotide (PDNA) of 1–50 K Dalton 0.001–0.4% (w/w), Lysimachia japonica extract 0.01–1% (w/w), green tea extract 0.01–1% (w/w), Terminalia chebula fruit extract 0.01–1% (w/w), Ligustrum japonicum leaf extract 0.01–1% (w/w), palmitoyl tripeptide-1 0.001–0.5% (w/w), and fragrance 0.2–0.4% (w/w). The cosmetic composition of the present invention provides excellent effects in preventing and alleviating acne. Acne (also known as Pimple or Zit) is a skin disease affecting the sebaceous glands within the hair follicles, manifesting as various skin lesions such as closed or open comedones, papules, pustules, cysts, and nodules. Acne causes inflammation of numerous hair follicles on the face of adolescent boys and girls, particularly on the cheeks and forehead, and can also occur on the chest or back. Initially, the hair follicle becomes clogged with cortex and keratin, forming a yellowish-white lump; sometimes, the apex of this lump may turn black. Furthermore, individuals prone to acne experience recurring episodes, leading to significant psychological stress. Acne is caused by excessive sebum production and pore closure; when sebum stagnates within the hair follicles and blocks air circulation, anaerobic bacteria residing within the follicles—such as Propionibacterium acnes (P. acnes), Propionibacterium granulosum (P. granulosum), and Propionibacterium avidum (P. avidum)—proliferate, leading to severe acne. These bacteria secrete lipolytic enzymes and chemical factors to produce free fatty acids, triggering an immune response in white blood cells. This damages the follicle walls, causing contents to leak into the dermis and triggering an inflammatory reaction. Methods to suppress acne include inhibiting excessive sebum production, inhibiting keratinization of the follicle walls, suppressing the proliferation of anaerobic acne bacteria, and minimizing inflammatory responses. Pharmacological treatments for acne include topical and oral therapies; topical antibiotics primarily used include combination agents containing clindamycin, erythromycin, and tetracycline. Generally, acne is treated by using salicylic acid or retinoic acid preparations, which are vitamin A derivatives, to inhibit or remove hyperkeratinization in the pores and facilitate secretion. Additionally, methods involving benzoyl peroxide, triclosan, sulfur, and tea tree oil are used to exfoliate the skin and alleviate inflammation through antibacterial action. However, these methods have drawbacks, such as minimal therapeutic efficacy and the occurrence of side effects including dermatitis, erythema, and allergies. Salicylic acid preparations not only have minimal therapeutic effects but can also cause skin redness, swelling, or skin aversion; while retinoic acid preparations are effective in inhibiting hyperkeratinization, they can lead to contact dermatitis, erythema, skin dryness, and peeling. Furthermore, benzoyl peroxide and triclosan preparations require caution in use due to side effects such as allergic contact dermatitis, scarring, and severe erythema. Meanwhile, azelaic acid preparations introduced relatively recently have reduced drug side effects, but they have the problem of being less effective compared to existing treatments. Polydeoxyribonucleotides (PDRN) are biomolecules composed of 13 or more nucleotide units. Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are polynucleotides that have distinct biological functions. Polydeoxyribonucleotide is produced by purifying DNA extracted from salmon milt and is also known as salmon injection. It has good skin penetration, minimizes side effects, and promotes cell generation and growth factors, so it is a drug that is safely approved for use in the regeneration after skin grafting, tissue repair, foot ulcers, tendinitis, and pain relief for osteoarthritis of the knee. Green tea refers to a perennial evergreen tree belonging to the tea family, distributed in regions such as Korea, Japan, and China. Since green tea is made using tea leaves, the term is used to describe tea produced using unoxidized leaves. Green tea contains catechins, a type of polyphenol, which prevent food from being converted into body fat and burn body fat, thereby aiding in weight loss. Furthermore, it possesses powerful antioxidant effects, eliminating free radicals to prevent aging and positively influencing the cardiovascular system and metabolism. Drinking green tea triggers detoxification and metabolism-boosting processes within the body through substances like tannins, resulting in a diuretic effect. Consuming green tea lowers cholesterol levels, promotes fat breakdown, prevents blood clot formation, and re