KR-102960995-B1 - Thrombectomy System comprising a Thrombus Retriever

Abstract

The present invention relates to a thrombus retriever comprising a wire member that has a straight linear shape at room temperature but deforms into a spiral shape under predetermined temperature conditions, and a marker located at the end of the wire member and provided to allow the position of the end of the wire member to be known from outside the body, wherein the wire is a nitinol alloy or a superelastic biomaterial having shape memory properties.

Inventors

• 김철생
• 장세림
• 서일원

Assignees

• 전북대학교산학협력단

Dates

Publication Date

20260507

Application Date

20220926

Claims (1)

1. As a thrombus removal system A thrombus retriever comprising a wire member that has a straight linear shape at room temperature and deforms into a spiral shape under predetermined temperature conditions, and a marker located at the end of the wire member and provided to allow the position of the end of the wire member to be known from outside the body; and An alternating magnetic field device that applies an alternating magnetic field to the wire member from the outside during the procedure to raise the temperature of the wire member to a temperature of 45°C or higher so that it unfolds spirally at an intended point; The above wire member is characterized by being a nitinol alloy or a superelastic biomaterial having shape memory properties, and The above alternating magnetic field device is characterized by controlling the application and intensity of the alternating magnetic field to specify the deployment position of the wire member, thereby controlling the attainment of the predetermined temperature. The above-mentioned thrombus retriever is formed such that the wire member is composed of a single wire structure excluding a tube or mesh structure, so as to minimize resistance to movement within the blood vessel when in the straight linear form, The above marker is characterized by being made of a metal material capable of ultrasonographic identification so as to be able to identify the end position of the wire member through ultrasound outside the body. Thrombosis removal system.

Description

Thrombectomy System comprising a Thrombus Retriever The present invention relates to a thrombus retriever comprising a wire member that has a straight linear shape at room temperature but deforms into a spiral shape under predetermined temperature conditions, and a marker located at the end of the wire member and provided to allow the position of the end of the wire member to be known from outside the body, wherein the wire is a nitinol alloy or a superelastic biomaterial having shape memory properties. Due to the global increase in the elderly population and cardiovascular diseases, the stroke management market is growing significantly, with the number of patients with ischemic stroke showing the highest growth. Endovascular treatment is known as an effective intervention for stroke. In the case of ischemic stroke, efficient thrombus removal is considered of the utmost importance. Since drug treatment requires administration within a relatively short period and is suitable for relatively small thrombi, physical thrombus removal is required in many cases. The Retriever is a medical device that removes blood clots causing strokes. It has the function of capturing and removing blood clots from blood vessels to restore normal blood flow and prevent further tissue necrosis. Therefore, technology is required to maximize efficient embedding into the thrombus and thrombus recovery rate. In the prior art Korean Patent Publication 10-2012-0102095, a technique for removing clots, thrombi, and foreign substances from blood vessels, particularly from cerebral blood vessels, is disclosed. Fig. 1 is a nitinol wire with a memorized spiral shape. Figure 2 shows a nitinol wire in a form elongated by more than five times. Figure 3 shows a nitinol wire undergoing a phase transition to its original form by applying heat at a specific temperature. FIG. 4 is a drawing illustrating the operation mode of a retriever according to the present invention. FIG. 5 is a drawing explaining the principle of generating heat by applying a magnetic field to a retriever according to the present invention. The following objects, other objects, features, and advantages of the present invention will be easily understood through the following preferred embodiments associated with the accompanying drawings. However, the present invention is not limited to the embodiments described herein and may be embodied in other forms. Rather, the embodiments introduced herein are provided to ensure that the disclosed content is thorough and complete, and to ensure that the spirit of the invention is sufficiently conveyed to those skilled in the art. The embodiments described and illustrated herein also include complementary embodiments. In this specification, the singular form includes the plural form unless specifically stated otherwise in the text. As used in this specification, 'comprise' and/or 'comprising' does not exclude the presence or addition of one or more other components to the mentioned component. The present invention will be described in detail below with reference to the drawings. In describing the specific embodiments below, various specific details have been included to explain the invention more specifically and to aid in understanding. However, a person with sufficient knowledge in the art to understand the invention will recognize that it can be used without these various specific details. In some cases, it is noted in advance that commonly known parts that are not significantly related to the invention are omitted to prevent confusion in describing the invention. The present invention provides the following means for solving the above problem. A wire member (2) that has a straight linear shape at room temperature and is deformed into a spiral shape under predetermined temperature conditions, and It includes a marker (3) located at the end of the wire member (2) and provided to allow the position of the end of the wire member (2) to be known from outside the body, and The above wire member (3) is characterized as being a nitinol alloy or a superelastic biomaterial having shape memory properties, thereby providing a thrombus retriever. This retriever is characterized by being manufactured from a wire capable of automatic shape recovery due to temperature changes. As such a wire, a nitinol alloy and a superelastic biomaterial with shape memory properties are preferred. Referring to FIGS. 1 to 3, in the case of FIG. 1, a wire member capable of shape recovery is provided so that it can return to a spiral shape as shown in the photograph at a specific temperature. However, at room temperature, the wire member takes on a straight linear shape as shown in FIG. 2. Subsequently, when a specific temperature condition (e.g., 45°C) is applied again, it returns to a spiral shape as shown in FIG. 3. The thrombus retriever according to the present invention is inserted into a blood vessel, such as an artery, of a patient in the form of a straight line a