KR-102961574-B1 - Composition for preventing hair loss or promoting hair growth

Abstract

The composition for preventing hair loss or promoting hair growth according to the embodiment may be characterized by including a mixture of Gynostemma pentaphyllum leaf extract, Erigeron annuus flower extract, Agastache rugosa extract, Euphorbia pekinensis extract, and Polygonum cuspidatum extract as an active ingredient.

Inventors

• 송진영

Assignees

• (주)에스투제약

Dates

Publication Date

20260507

Application Date

20231213

Claims (7)

1. It contains a mixture of Gynostemma pentaphyllum leaf extract, Erigeron annuus flower extract, Agastache rugosa extract, Euphorbia pekinensis extract, and Polygonum cuspidatum extract as active ingredients, The above-mentioned Gynostemma pentaphyllum leaf extract is obtained from the 1-1 extract extracted from the 1-1 mixed solution in which Gynostemma pentaphyllum leaves and water are mixed, and the 1-2 extract extracted from the 1-2 mixed solution in which Gynostemma pentaphyllum leaves and an aqueous ethanol solution are mixed. The above-mentioned wild daisy flower extract is, (a) Obtain the 2-1 extract from the 2-1 mixed solution of a mixture of horseweed flowers and diethyl ether, and (b) A 2-2 extract is obtained from a 2-2 mixed solution in which the 2-1 extract and ethyl acetate are mixed, and (c) A 2-3 extract is obtained from a 2-3 mixed solution in which the 2-2 extract and methanol are mixed, and (d) The above 2-3 extracts are obtained by concentrating under reduced pressure, and The above-mentioned Agastache extract is, (a) Obtain the 3-1 extract from the 3-1 mixed solution in which Agastache rugosa and an aqueous ethanol solution are mixed, and (b) The above 3-1 extract is filtered and concentrated under reduced pressure to obtain the 3-2 extract, and (c) A 3-3 extract is obtained from a 3-2 mixed solution in which the 3-2 extract is mixed with purified water and diethyl ether, and (d) A 3-4 extract is obtained from a 3-3 mixed solution in which the 3-3 extract is mixed with ethyl acetate, and (e) The above 3-4 extract is obtained from a 3-4 mixed solution mixed with n-butanol, and The above-mentioned Euphorbia pekinensis extract is, (a) The above-mentioned amphibole is dried and crushed to obtain a first crushed product, and (b) freeze-dry and grind the first crushed material to obtain a second crushed material, and (c) A mixed solution obtained by mixing the second pulverized material with distilled water, and (d) The above mixed solution is obtained by stirring and cooling, and The above Polygonum multiflorum extract is, (a) Obtain the 4-1 extract from the 4-1 mixed solution containing the roots of the whole plant of Polygonum multiflorum, and (b) Obtain a 4-2 extract from a 4-2 mixed solution containing at least one selected from the group including flowers, leaves, and stems of the whole plant of Polygonum multiflorum, and (c) A 4-3 extract is obtained from a 4-3 mixed solution containing the 4-1 extract and the 4-2 extract, and (d) A composition for preventing hair loss or promoting hair growth, characterized by being obtained by concentrating the above 4-3 extract under reduced pressure.
2. In Article 1, The above composition comprises, based on 100 parts by weight of the Euphorbia pekinensis extract, 10 to 90 parts by weight of the Gynostemma pentaphyllum leaf extract, 10 to 80 parts by weight of the Erigeron annuus flower extract, 10 to 150 parts by weight of the Agastache rugosa extract, and 10 to 90 parts by weight of the Polygonum cuspidatum extract. Composition for preventing hair loss or promoting hair growth.
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Description

Composition for preventing hair loss or promoting hair growth The present invention relates to a composition for preventing hair loss or promoting hair growth, and more specifically, to a composition for preventing hair loss or promoting hair growth characterized by comprising, as an active ingredient, a mixture of Gynostemma pentaphyllum leaf extract, Erigeron annuus flower extract, Agastache rugosa extract, Euphorbia pekinensis extract, and Polygonum cuspidatum extract. Generally, known causes of hair loss include the effects of male hormones, decreased metabolic function of the hair roots due to reduced blood flow resulting from poor blood circulation, nutritional deficiencies, side effects of medications, scalp damage caused by dandruff fungi or bacteria, and genetic factors. Additionally, it is known that the scalp and hair are damaged by irritation caused by excessive shampooing, drying, and hairstyling, as well as by the removal of the scalp's natural moisturizing components by chemical cleansing agents. In particular, due to the recent excessive increase in stress resulting from changes in the social environment, the number of people struggling with symptoms of hair loss and damage is on the rise, and the boundaries and limitations regarding age and gender are also expanding. On average, a person has approximately 100,000 to 120,000 hairs. Hair follows a life cycle consisting of development, growth, regression, and resting phases; it is normal for about 50 to 100 hairs to fall out daily while in the resting phase. Hair grows for a certain period, then falls out and new hair grows in its place. Unlike fingernails or toenails, it follows a cycle of "grow-rest-shed." In the case of molting animals, the entire hair cycle is uniform, resulting in the so-called molting where hair falls out and regrows simultaneously. However, because human hair has an independent hair cycle, the number of hairs remains constant without molting. Human hair falls out after three years of growth, and new hair grows in the same spot three months later. There are about 100,000 to 120,000 hairs; of these, about 70 fall out daily, and the 70 hairs that fell out three months ago grow back, ensuring that the total number of hairs always remains between 100,000 and 120,000. Each hair has a different cycle, growing and falling out through the anagen, catagen, and telogen phases. This cycle repeats over 3 to 6 years, resulting in an average of 50 to 100 hairs falling out daily. Hair is rooted in the scalp and receives nutrients from the blood. However, if the capillaries constrict and the scalp thins over a long period, reaching a state where hair cannot develop normally, the hair in that area gradually becomes thinner, and the lifespan of the hair in that specific area is shortened. Not only does hair with a shortened lifespan fall out easily, but hair cannot grow back from the follicles where it has fallen out as described above, eventually leading to thinning hair. Furthermore, testosterone, which is known to interfere with the production of energy necessary for hair growth and development, is converted into DHT (Dihydrotesosterone), whose activity is increased by the action of 5α-reductase distributed around the hair follicle. Activated DHT binds to androgen receptors, shortening the hair growth phase and shrinking the size of the hair follicle, thereby gradually making the hair thinner and eventually causing hair loss. Various hair loss prevention agents and hair growth promoters are being developed for the purpose of preventing thinning hair caused by the aforementioned hair loss phenomenon and enabling active hair growth in the pores of the scalp. FIGS. 1 to 5 are drawings referenced to explain experimental examples using a composition for preventing hair loss or promoting hair growth according to the present invention. The present invention will be described in detail below. Prior to this, terms and words used in this specification and claims should not be interpreted as being limited to their ordinary or dictionary meanings, but should be interpreted in a meaning and concept consistent with the technical spirit of the present invention, based on the principle that the inventor can appropriately define the concept of the terms to best describe his invention. Accordingly, the configurations described in the embodiments described in this specification are merely one preferred embodiment of the present invention and do not represent all of the technical spirit of the present invention; therefore, it should be understood that various equivalents and modifications capable of replacing them may exist at the time of filing this application. [Composition for preventing hair loss or promoting hair growth] The composition for preventing hair loss or promoting hair growth according to the embodiment is characterized by containing a complex extract based on herbal medicines or natural materials. The composition for preventing hair loss o