KR-102963082-B1 - Method, Device, and System for Stimulating Brain Network

KR102963082B1KR 102963082 B1KR102963082 B1KR 102963082B1KR-102963082-B1

Abstract

A brain network stimulation method according to one embodiment of the present invention may include: a step of distinguishing and providing a user with a predetermined first content and a predetermined second content; a step of delivering a predetermined stimulus to the user's brain only when the second content is provided to the user; and a step of inducing the brain to switch from a DMN (Default Mode Network) to a CEN (Central Executive Network) by activating the brain's SN (Salience Network) through the stimulus.

Inventors

권구성
이승우
원혁

Assignees

(주)리솔

Dates

Publication Date: 20260513
Application Date: 20250310

Claims (20)

A supply unit that distinguishes between a pre-designated first content and a pre-designated second content and provides them to the user; A stimulation unit that delivers a preset stimulus to the brain of the user; and A control unit that controls the stimulation to be transmitted to the user's brain only when the second content is provided to the user; is included. Only when the above-mentioned second content is provided to the user is the stimulus transmitted to the user's brain and the SN (Salience Network) activated, thereby inducing the brain to switch from the DMN (Default Mode Network) to the CEN (Central Executive Network), and The above stimulus is transmitted to the DLPFC (Dorsolateral Prefrontal Cortex) region to induce activation of the SN, and The above stimulus induces the activation of the SN by entraining synchronized vibrations in multiple regions of the brain. The above-mentioned synchronized vibration is a gamma vibration of 30 Hz or higher, and The above stimulus is, It includes at least one of tACS (Transcranial Alternating Current Stimulation), tDCS (Transcranial Direct Current Stimulation), tMS (Transcranial Magnetic Stimulation), TUS (Transcranial Ultrasound Stimulation), transcranial photobiomodulation (tPBM), and sensory stimulation, and The above sensory stimulation is, It includes at least one of visual stimulation, auditory stimulation, tactile/vibratory stimulation, and olfactory and gustatory stimulation, and The above-mentioned first content is noise content with low relevance to the user, and The above second content is a device that is mission content highly relevant to the user.
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In Article 1, When the above SN is activated and switches from the above DMN to the above CEN, A device that performs at least one of working memory, cognitive flexibility, executive function, decision making and problem-solving, attention control, and inhibition control.
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In Article 1, When the above-mentioned first content is provided to the user, By the above-mentioned stimulation unit, a pre-specified noise stimulus is transmitted to the user's brain, and The above noise stimulus is a stimulus that entrains the synchronized oscillation associated with the deactivation of the above SN, and The synchronized vibration that tunes according to the above noise stimulus is, A device having alpha waves (α) vibrations of 8–13 Hz or theta waves (θ) vibrations of 4–7 Hz.
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In Article 1, The stimulus for the above entrainment is, A multi-stimulation device in which at least two of the above tACS, tDCS, tMS, TUS, tPBM and sensory stimulation are applied simultaneously.
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In Article 1, The above-mentioned first content is sound information that includes at least some random sound, and The second content above is sound information comprising at least one of music related to the user, environment sound related to the user, and voice related to the user, and A device in which the gamma vibration is tuned only when the above-mentioned second content is transmitted, and the SN is activated by the gamma vibration tuning to switch from the DMN to the CEN.
In Article 10, The device, wherein the second content is learning sound information comprising at least some of the pre-specified English words and idioms that the user wishes to learn.
In Article 1, The first content above is image information that includes at least some random images not related to the user, and The second content above is image information that includes at least some images related to the user, and A device in which the gamma vibration is tuned only when the second content is transmitted, and the SN is activated by the gamma vibration tuning to switch from the DMN to the CEN.
In Article 1, The above-mentioned first content simultaneously includes 'sound information' comprising at least some random sound and 'image information' comprising at least some random image unrelated to the user, and The second content above simultaneously includes 'sound information' comprising at least one of music related to the user, environment sound related to the user, and voice related to the user, and 'image information' comprising at least a part of an image related to the user. A device in which the gamma vibration is tuned only when the second content is transmitted, and the SN is activated by the gamma vibration tuning to switch from the DMN to the CEN.
In Article 1, The above-mentioned first content is lecture content information that the user studies, and The above second content is specific lecture area information containing pre-designated important learning content among the above lecture content information, and A device in which the gamma vibration is tuned only when the second content is transmitted, and the SN is activated by the gamma vibration tuning to switch from the DMN to the CEN.
In Article 1, The first content above is random information that guides the user's movements, which the user can perform without concentration, and The second content above is information that guides the user's movements requiring the user's concentration, and A device in which the gamma vibration is tuned only when the second content is transmitted, and the SN is activated by the gamma vibration tuning to switch from the DMN to the CEN.
In Article 1, If the above user is a patient with depression, A device for resolving the problem of excessive activation of the DMN and decreased function of the CEN in patients with depression by activating the SN through the above stimulus and training the switching process between the DMN and CEN according to the activation of the SN.
In Article 1, If the above user is a patient with an anxiety disorder, A device for resolving the problem of excessive activation of the SN and imbalance between the DMN and the CEN in patients with anxiety disorders by activating the SN through the above stimulus and training the switching process between the DMN and the CEN according to the activation of the SN.
In Article 1, If the above user is a schizophrenic patient, A device for resolving the problem of impaired function of the CEN and abnormality of the SN in a schizophrenic patient by activating the SN through the above stimulus and training the switching process between the DMN and CEN according to the activation of the SN.
In Article 1, If the above user is an ADHD patient, A device for resolving the problem of reduced function of the CEN in ADHD patients by activating the SN through the above stimulus and training the switching process between the DMN and CEN according to the activation of the SN.
Step 1: Distinguishing between a pre-designated first content and a pre-designated second content and providing them to the user; A second step of delivering a predetermined stimulus to the brain of the user; A third step of controlling the stimulus to be transmitted to the user's brain only when the second content is provided to the user; and A fourth step of monitoring whether the brain switches from the DMN (Default Mode Network) to the CEN (Central Executive Network) as the above stimulus is transmitted to the user's brain and the SN (Salience Network) is activated; The above stimulus is transmitted to the DLPFC (Dorsolateral Prefrontal Cortex) region to induce activation of the SN, and The above stimulus induces the activation of the SN by entraining synchronized vibrations in multiple regions of the brain. The above-mentioned synchronized vibration is a gamma vibration of 30 Hz or higher, and The above stimulus is, It includes at least one of tACS (Transcranial Alternating Current Stimulation), tDCS (Transcranial Direct Current Stimulation), tMS (Transcranial Magnetic Stimulation), TUS (Transcranial Ultrasound Stimulation), transcranial photobiomodulation (tPBM), and sensory stimulation, and The above sensory stimulation is, It includes at least one of visual stimulation, auditory stimulation, tactile/vibratory stimulation, and olfactory and gustatory stimulation, and The above-mentioned first content is noise content with low relevance to the user, and The above second content is a brain network monitoring method, which is mission content highly relevant to the user.

Description

Method, Device, and System for Stimulating Brain Network The present invention relates to a method, apparatus, and system for stimulating a brain network. More specifically, it relates to a method, apparatus, and system for stimulating a brain network that activates the importance network (SN) of the brain through specific stimulation when pre-specified content is provided, thereby inducing a transition from the basic mode network (DMN) to the central execution network (CEN). Recent neuroscience research is revealing that abnormal interactions in brain networks related to various neuropsychiatric disorders and cognitive functions play a significant role. Against this backdrop, the Triple-Network Model was proposed, which is based on the concept that the interaction between the Default Mode Network (DMN), Salience Network (SN), and Central Executive Network (CEN) plays a key role in mental health and cognitive regulation. Interactions and anticorrelations exist between the aforementioned networks. In other words, SN plays a role in regulating the transition between DMN and CEN, and the process in which DMN is deactivated and CEN is activated during the performance of a specific task is important. DMN and CEN have an anticorrelation relationship; when DMN is activated, CEN activity decreases, and conversely, when CEN is activated, DMN activity is inhibited. If the SN does not function normally, the balance between the DMN and CEN is disrupted, which can lead to problems such as attention deficit, excessive internal thinking (rumination), or executive dysfunction. Figure 1 is a diagram illustrating a large-scale brain network. Figure 2 is a diagram illustrating the Triple-network Model, a brain network model in which SN facilitates the transition between DMN and CEN. Figure 3 is a diagram illustrating the Triple-network Model and mental illness. Figure 4 illustrates an example of network normalization through auditory stimulation. Figure 5 illustrates an example of network normalization through visual stimulation. Figure 6 illustrates an example of network normalization through sensorimotor stimulation. Figure 7 illustrates an example of network normalization through visual, sound, and tACS stimuli as a concept related to English learning. Figure 8 illustrates an example of network normalization through visual, sound, and tACS stimulation as a concept related to internet lecture learning. FIG. 9 illustrates a specific example of using visual, sound, and tACS in relation to the Internet lecture learning concept according to the present invention. FIG. 10 illustrates an example of an implementation of internet lecture learning according to the present invention. FIG. 11 illustrates a specific example of the present invention being applied to an internet lecture. FIG. 12 illustrates an example of a brain network stimulation device and system related to the present invention. Figure 13 is a dFNC volatility analysis graph and a comparison chart of connectivity between networks. Figure 14 shows a dFNC state analysis diagram. In describing the embodiments of this specification, if it is determined that a detailed description of known configurations or functions could obscure the essence of the embodiments of this specification, such detailed description is omitted. Additionally, parts of the drawings unrelated to the description of the embodiments of this specification have been omitted, and similar parts are denoted by similar reference numerals. In the embodiments of this specification, when a component is described as being "connected," "combined," or "joined" with another component, this may include not only a direct connection but also an indirect connection in which another component exists in between. Furthermore, when a component is described as "comprising" or "having" another component, this means that, unless specifically stated otherwise, it does not exclude the other component but may include additional components. In the embodiments of this specification, terms such as first, second, etc. are used solely for the purpose of distinguishing one component from another component and do not limit the order or importance of the components unless specifically stated otherwise. Accordingly, within the scope of the embodiments of this specification, the first component in an embodiment may be referred to as the second component in another embodiment, and likewise, the second component in an embodiment may be referred to as the first component in another embodiment. In the embodiments of this specification, distinct components are intended to clearly explain their respective features and do not imply that the components are necessarily separated. That is, multiple components may be integrated to form a single hardware or software unit, or a single component may be distributed to form multiple hardware or software units. Therefore, such integrated or distributed embodiments are included within the scope of the embo