KR-102964214-B1 - Disinfection composition

KR102964214B1KR 102964214 B1KR102964214 B1KR 102964214B1KR-102964214-B1

Abstract

The present invention is a disinfecting composition comprising 0.001 mass% to 5 mass% of an MPC copolymer containing a constituent unit based on 2-(meth)acryloyloxyethyl phosphorylcholine, 5 mass% to 90 mass% of a lower alcohol, and 0.01 mass% to 10 mass% of a fatty acid ester-based nonionic surfactant, wherein the MPC copolymer comprises one or more copolymers selected from the group consisting of MPC copolymer a having a weight average molecular weight of 10,000 to 400,000 and MPC copolymer b having a weight average molecular weight of 800,000 to 1,800,000. According to the present invention, a disinfecting composition can be provided that has excellent foam persistence when dispensed as foam and has a moist sensation when applied.

Inventors

하라 마사오
사쿠라이 스케

Assignees

니치유 가부시키가이샤

Dates

Publication Date: 20260512
Application Date: 20210218
Priority Date: 20200226

Claims (3)

A disinfecting composition comprising 0.001 mass% to 5 mass% of an MPC copolymer containing a constituent unit based on 2-(meth)acryloyloxyethyl phosphorylcholine (MPC), 5 mass% to 90 mass% of a lower alcohol, and 0.01 mass% to 10 mass% of a fatty acid ester-based nonionic surfactant, wherein the lower alcohol is a monohydric alcohol having 5 or fewer carbon atoms, and wherein the MPC copolymer comprises an MPC copolymer a having a weight average molecular weight of 10,000 to 400,000 and an MPC copolymer b having a weight average molecular weight of 900,000 to 1,800,000.
In Article 1, A disinfectant composition wherein the lower alcohol is one or more selected from the group consisting of ethanol and isopropanol.
In Article 1 or Article 2, Additionally, a disinfection composition containing 0.01 mass% to 5 mass% of a disinfectant.

Description

Disinfection composition The present invention relates to a disinfectant composition with excellent usability. In recent years, concerns have arisen regarding the spread of infectious diseases caused by pathogenic viruses and bacteria, leading to the development of various infection prevention products. Among these, disinfectant compositions have become widely popular due to their advantage of being able to sterilize and disinfect simply by applying them to the hands. In the case of disinfectant compositions, research has been conducted on incorporating specific bactericidal components or adjusting the pH of the composition to a specific range in order to provide a broad bactericidal spectrum and enhance bactericidal power. In order to improve usability, such as quick drying and non-stickiness, while maintaining bactericidal power, research is being conducted on disinfectant compositions containing a high amount of lower alcohols such as ethanol, such as adjusting the type of thickener or the pH of the composition to a specific range. For example, a gel-type hand disinfectant has been proposed in which a carboxyvinyl polymer is neutralized with an alkali metal hydroxide and a polyoxyethylene glycol having a specific molecular weight prevents cloudiness of the composition (Patent Document 1). However, since the above disinfectant compositions do not have a pH in the neutral range or contain a relatively large amount of lower alcohol, there was a concern that they could cause hand roughness in cases where the disinfectant compositions are used frequently, such as by medical personnel. Therefore, in order to impart a hand roughness prevention effect to the disinfectant compositions, additional research has been conducted, such as incorporating moisturizers like glycerin, propylene glycol, and sorbitol (Patent Document 2), or incorporating water-soluble polyalcohols and fatty acid triglycerides (Patent Document 3). In addition, foam-type hand sanitizer compositions are being used these days due to the advantage of being easy to identify the application area and easy to spread. Foam-type hand sanitizer compositions contain fatty acid ester-based nonionic surfactants as foaming agents, are drawn up from a pump through a mesh, and are discharged as an aggregate of fine foams. Although lower alcohols are also incorporated into foam-type hand sanitizer compositions for the purpose of applicationability and quick drying, there was a problem that the foam of the discharged hand sanitizer composition had poor persistence and was defoamed before being spread on the hands because lower alcohols also act as defoaming agents. [Disinfection composition] The disinfecting composition of the present invention comprises 0.001 mass% to 5 mass% of an MPC copolymer comprising a constituent unit based on 2-(meth)acryloyloxyethyl phosphorylcholine, 5 mass% to 90 mass% of a lower alcohol, and 0.01 mass% to 10 mass% of a fatty acid ester-based nonionic surfactant, wherein the MPC copolymer comprises one or more copolymers selected from the group consisting of MPC copolymer a having a weight average molecular weight of 10,000 to 400,000 and MPC copolymer b having a weight average molecular weight of 800,000 to 1,800,000. Details of the present invention are described below. (MPC copolymer) The disinfectant composition of the present invention contains an MPC copolymer comprising a constituent unit based on 2-(meth)acryloyloxyethylphosphorylcholine (MPC). The MPC copolymer is a copolymer comprising a constituent unit based on MPC and a constituent unit based on a monomer other than MPC. As the constituent unit based on a monomer other than MPC, a constituent unit based on a hydrophobic monomer described below is preferred. <Constituent units based on MPC> A constituent unit based on MPC is represented by the following formula (1). Meanwhile, in this specification, "(meth)acryloyl" means "acryloyl or methacryloyl". [Chemical Formula 1] In formula (1), R1 represents a hydrogen atom or a methyl group. Constituent units based on hydrophobic monomers Examples of constituent units based on the hydrophobic monomer include constituent units based on (meth)acrylate alkyl esters, (meth)acrylamide derivatives, etc. A constituent unit based on an alkyl (meth)acrylate ester is represented by the following formula (2). Here, “(meth)acrylic acid” means “acrylic acid or methacrylic acid”. [Chemical Formula 2] In formula (2), R2 represents a hydrogen atom or a methyl group, and R3 represents an alkyl group having 1 to 24 carbon atoms. In formula (2), the alkyl group represented by R3 is a straight-chain or branched alkyl group having 1 to 24 carbon atoms, and may have some of the hydrogen atoms of the alkyl group substituted. Examples of straight-chain or branched alkyl groups having 1 to 24 carbon atoms include methyl, ethyl, propyl, butyl, pentyl, hexyl, octyl, 2-ethylhexyl, decyl, dodecyl, tetradecyl, hexadecyl, octadecyl, behenyl, etc. Accordingly,